ARTICLES
Fecal Elastase 1 As a Diagnostic Marker for Exocrine Pancreatic Insufficiency
Researchers recently evaluated the clinical utility of fecal concentration of elastase 1 as a means of identifying exocrine pancreatic insufficiency in patients with chronic pancreatitis.
Sejal Saraiya, PharmD
Each year approximately 63,000 persons in the US will be diagnosed with thyroid cancer, placing it among the top 10 most common cancers in the country.
2015 Volume 3 Number 1
Xtandi Improves Progression-Free Survival Over Casodex in Metastatic Prostate Cancer
Recent results from the phase 2 TERRAIN trial showed Xtandi increased progression-free survival by nearly 10 months compared with Casodex in patients with metastatic castration-resistant prostate cancer.
A Case of Munchausen by Proxy Syndrome?
The mother of a 9-year-old boy with Hirschsprung’s disease has been indicted of endangering children and could face up to 8 years in prison.
Blizzard Fizzles, Hospitals Relieved
Hospitals in New York and New Jersey expect to return to normal by tomorrow morning, after making extensive blizzard readiness preparations that disrupted schedules and had the public on edge.State of emergency declarations were lifted this morning, as the storm that was supposed to be “snowpocalypse” or “snowmageddon” turned east from its predicted path by 50 miles and spared much of the NY-NJ region that was expecting it to be a winter version of 2012's Super Storm Sandy.
Alternatives to Testosterone Replacement Therapy
Adult male hypogonadism (HG) is the most common form of diminished gonadal activity in men. Most clinicians prescribe testosterone replacement therapy to treat primary HG, but other therapeutic options are available.
Critical Illness and Renal Clearance: Why So Fast?
Renal clearance can be significantly elevated in the critically ill. Treating these patients with renally cleared drugs can present a problem. Drugs—whisked through the body with greater than expected efficiency, a process called augmented renal clearance (ARC)—reach only suboptimal levels and, consequently, patients experience no improvement or actual clinical decline. ARC is often associated with elevated urinary creatinine clearance.
Rogue Breast Cancer: The Triple Negative Dilemma
In March 2014, the Society of Surgical Oncology Susan G. Komen for the Cure Symposium focused on the literature on the epidemiology, molecular pathology, and therapy considerations of triple-negative breast cancer. The Annals of Surgical Oncology has published a summary of this work ahead of print.
Data Mining Being Harnessed to Power Precision Medicine
Every time you check out at the supermarket with your customer loyalty card, a computer makes a record of your purchases, which links to your demographic profile.
Selective Kallikrein Inhibitor BCX4161 Given Orphan Drug Status for Hereditary Angioedema
OPuS-1 included 24 patients with severe HAE (mean age, 42 years) who were randomly assigned to receive a 400-mg dose of BCX4161 three times daily or placebo for 4 weeks before crossing over to the other arm.