Active Pharmacovigilance and Healthcare UtilizationThis study highlights the potential value of innovative ways of collecting information about adverse drug events directly from patients.

A Systematic Review of Reference Pricing: Implications for US Prescription Drug SpendingReference pricing is an effective cost-containment tool widely used in other countries; it may be an attractive policy strategy for the US healthcare system.

Care Coordination Agreements: Barriers, Facilitators, and Lessons LearnedPrimary care providers have developed standing agreements with other healthcare providers and community-based organizations to coordinate care. Early experiences with these agreements are discussed.

How Comorbidities and Preoperative Expenditures Correlate With Postoperative Adverse OutcomesAdjusting for patients’ covariates, postoperative complications and mortality among geriatric surgical patients exhibited an age-dependent, illness-related, and preoperative medical expense–associated pattern under universal healthcare coverage.

Physician Factors That Influence Patient Referrals to End-of-Life CareThis study used multivariate models to identify physician specialty and comfort with end-of-life discussions, both of which are associated with end-of-life referrals.

Identification of and Intervention to Address Therapeutic Gaps in CareA program identifying and resolving care gaps involving community pharmacists resulted in increased adherence and omission gaps closure and fewer adherence gap reopenings.

EMR-Based Medication Adherence Metric Markedly Enhances Identification of Nonadherent PatientsIntegration of written-prescription data into medication adherence measures doubled the number of patients identified as nonadherent and improved prediction of follow-up LDL cholesterol.

Financial Incentives and Physician Commitment to Guideline-Recommended Hypertension ManagementFinancial incentives may not be strong enough to influence physician goal commitment to guideline-recommended hypertension care when providers attribute performance to forces beyond their control.

Identifying Frail Older People Using Predictive ModelingThe frailty determination of the Adjusted Clinical Groups–diagnoses based predictive model identified frail elders with moderate success compared with a validated screening questionnaire.