Clinical Study Summaries
STUDY SUMMARY: HeartFlow Continues to Deepen Market Access
1. American Heart Association. Cardiovascular disease: a costly burden for America—projections through 2035. AHA website. www.heart.org/idc/groups/heart-public/@wcm/@adv/documents/downloadable/ucm_491543.pdf. Published 2017. Accessed July 6, 2017.
2. Mozaffarian D, Benjamin EJ, Go AS, et al; American Heart Association Statistics Committee; Stroke Statistics Subcommittee. Heart disease and stroke statistics-2016 update: a report from the American Heart Association. Circulation. 2016;133(4):e38-e360. doi: 10.1161/CIR.0000000000000350.
3. Douglas, PS, Pontone G, Hlatky MA, et al; PLATFORM Investigators. Clinical outcomes of fractional flow reserve by computed tomographic angiography-guided diagnostic strategies vs. usual care in patients with suspected coronary artery disease: the prospective longitudinal trial of FFR(CT): outcome and resource impacts study. Eur Heart J. 2015;36(47):3359-3367. doi: 10.1093/eurheartj/ehv444.
4. Chinnaiyan KM, Akasaka T, Amano T, et al. Rationale, design and goals of the HeartFlow assessing diagnostic value of non-invasive FFRCT in Coronary Care (ADVANCE) registry. J Cardiovasc Comput Tomogr. 2017;11(1):62-67. doi: 10.1016/j.jcct.2016.12.002.
5. Rajani R, Modi B, Ntalas I, Curzen N. Non-invasive fractional flow reserve using computed tomographic angiography: where are we now and where are we going? Heart. 2017 pii: heartjnl-2016-311029. doi: 10.1136/heartjnl-2016-311029.
6. Qi X, Fan G, Zhu, D, et al; Comprehensive assessment of coronary fractional flow reserve. Arch Med Sci. 2015;11(3):483-493. doi: 10.5114/aoms.2015.52351
7. Vergallo R, Uemura S, Soeda T, et al; Prevalence and Predictors of Multiple Coronary Plaque Ruptures: In Vivo 3-Vessel Optical Coherence Tomography Imaging Study. Arterioscler Thromb Vasc Biol 2016;36:2229-38. doi: 10.1161/ATVBAHA.116.307891
8. Hakeem A, Edupuganti MM, Almomani A, et al; Long-Term Prognosis of Deferred Acute Coronary Syndrome Lesions Based on Nonischemic Fractional Flow Reserve. J Am Coll Cardiol 2016;68:1181-91. doi: 10.1016/j.jacc.2016.06.035
9. National Institute for Health and Care Excellence. HeartFlow FFRCT for estimating fractional flow reserve from coronary CT angiography. NICE website. www.nice.org.uk/guidance/mtg32. Published February 13, 2017. Accessed July 5 2017.
10. Patel MR, Calhoon JH, Dehmer GJ, et al. ACC/AATS/AHA/ASE/ASNC/SCAI/SCCT/STS 2017 Appropriate use criteria for coronary revascularization in patients with stable ischemic heart disease: a report of the American College of Cardiology Appropriate Use Criteria Task Force, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, and Society of Thoracic Surgeons. J Am Coll Cardiol. 2017;69(17):2212-2241. doi: 10.1016/j.jacc.2017.02.001.
11. Douglas PS, De Bruyne B, Pontone G, et al; PLATFORM Investigators. 1-year outcomes of FFRCT-guided care in patients with suspected coronary disease: the PLATFORM study. J Am Coll Cardiol. 2016;68(5):435-445. doi: 10.1016/j.jacc.2016.05.057.
12. Kitabata H, Leipsic J, Patel M, et al. Incidence and predictors of lesion specific ischemia by FFRCT: Learnings from the international ADVANCE registry [abstract 1297-343]. J Am Coll Cardiol. 2017;69(suppl 11):297.
13. Rabbat M, Kauh B, Pontone G, Norgaard B, Lopez J, Mathew V. Fractional flow reserve derived from coronary computed tomography safely reduces invasive coronary angiography rates and cost in patients with stable coronary artery disease [abstract 1126-333]. J Am Coll Cardiol. 2017;69(suppl 11):72.
14. Zarins CK, Taylor CA, Min, JK; Computed fractional flow reserve (FFTCT) derived from coronary CT angiography. J of Cardiovasc. Trans. Res. 2013;6:708–714. doi: 10.1007/s12265-013-9498-4
15. Hannawi B, Lam WW, Wang S, et al. Current use of fractional flow reserve: a nationwide survey. Tex Heart Inst J. 2014;41(6):579-584. doi: 10.14503/THIJ-13-3917
16. BlueCross BlueShield Association. Coronary computed tomography angiography with selective noninvasive fractional flow reserve. Published June 2017. Accessed July 11, 2017.
17. Aetna. Cardiac CT, coronary CT angiography calcium scoring and CT fractional flow reserve. Aetna website. www.aetna.com/cpb/medical/data/200_299/0228.html. Updated May 12, 2017. Accessed July 5, 2017.
18. HeartFlow announces American Medical Association issues unique Category III CPT codes for HeartFlow FFRct [news release]. Redwood City, CA: Heartflow, Inc; July 5, 2017.