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Clinical Trial Designs in PAH: Shifting From Functional Measurements to Long-term Clinical Outcomes
Sean M. Studer, MD, MSc, and Robert J. Gilkin, Jr, RPh, MBA
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Participating Faculty: Clinical Trial Designs in PAH: Shifting From Functional Measurements to Long-term Clinical Outcomes
Sean M. Studer, MD, MSc, and Robert J. Gilkin, Jr, RPh, MBA

Participating Faculty: Clinical Trial Designs in PAH: Shifting From Functional Measurements to Long-term Clinical Outcomes

Sean M. Studer, MD, MSc, and Robert J. Gilkin, Jr, RPh, MBA
This supplement to The American Journal of Managed Care provides an overview of the economic burden of pulmonary arterial hypertension (PAH) and the current state of its management. Also discussed is the evolution of clinical trial design in PAH that includes a move away from the use of 6-minute walk distance as a primary end point and toward morbidity and mortality composite end points that better reflect disease progression.
This supplement was sponsored by Actelion Pharmaceuticals US, Inc.

Faculty

Sean M. Studer, MD, MSc
Chief of Medicine
Associate Professor of Clinical Medicine
New York University
New York, New York

Robert J. Gilkin, Jr, RPh, MBA
Vice President
Gemini Healthcare, LLC
Westbrook, Connecticut

Faculty Disclosures

These faculty report relationships with the following organizations:

Sean M. Studer, MD, MSc
Consultant or paid advisory board/lecture fees:
Actelion Pharmaceuticals, Bayer, Gilead, and United Therapeutics Corporation.

Robert J. Gilkin, Jr, RPh, MBA
Consultant:
Actelion Pharmaceuticals and Pfizer.

Signed disclosures are on file at the office of The American Journal of Managed Care, Plainsboro, New Jersey.


Opinions expressed by authors, contributors, and advertisers are their own and not necessarily those of Clinical Care Targeted Communications, LLC, d/b/a Managed Care & Healthcare Communications, LLC, the editorial staff, or any member of the editorial advisory board. Clinical Care Targeted Communications, LLC, d/b/a Managed Care & Healthcare Communications, LLC, is not responsible for accuracy of dosages given in articles printed herein. The appearance of advertisements in this publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality, or safety. Clinical Care Targeted Communications, LLC, d/b/a Managed Care & Healthcare Communications, LLC, disclaims responsibility for any injury to persons or property resulting from any ideas or products referred to in the articles or advertisements.

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