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Supplements Use of Opioid Analgesics in Managed Care Practice: Challenges, Controversies, REMS, and Optimizing P
The Continued Rise of Opioid Misuse: Opioid Use Disorder
Bill McCarberg, MD, FABPM
Implications of the Extended-Release/Long-Acting Opioid REMS for Managed Care
James B. Ray, PharmD, CPE
The Economics of Opioids: Abuse, REMS, and Treatment Benefits
Jeffrey Fudin, PharmD, DAAPM, FCCP, FASHP
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Participating Faculty: Use of Opioid Analgesics in Managed Care Practice: Challenges, Controversies, REMS, and Optimizing Patient Management [CME/CPE]

Participating Faculty: Use of Opioid Analgesics in Managed Care Practice: Challenges, Controversies, REMS, and Optimizing Patient Management [CME/CPE]

This supplement to The American Journal of Managed Care describes patients with or at risk for opioid use disorder to facilitate early intervention and treatment, outline the clinical and economic impact of opioid misuse and the implementation of a REMS program into managed care practice, and distinguish between general and productspecific drug information surrounding different extended- release and long-acting opioid analgesics, including updated safety labeling.
Faculty
Jeffrey Fudin, PharmD, DAAPM, FCCP, FASHP
Adjunct Associate Professor
Western New England University
College of Pharmacy
Springfield, Massachusetts

Adjunct Assistant Professor of Pharmacy Practice
University of Connecticut School of Pharmacy
Storrs, Connecticut

Clinical Pharmacy Specialist in Pain Management
Director
PGY2 Pharmacy Pain & Palliative Care Residency
Stratton VA Medical Center
Albany, New York*

Bill McCarberg, MD, FABPM
Physician
Neighborhood Healthcare
Medical Director
Elizabeth Hospice
Escondido, California

Adjunct Assistant Clinical Professor
University of California San Diego

President
American Academy of Pain Medicine

James B. Ray, PharmD, CPE
James A. Otterbeck OnePoint Patient Care
Clinical Associate Professor in Hospice and Palliative Care
Department of Pharmacy Practice and Science
University of Iowa College of Pharmacy
Iowa City, Iowa

Editorial Support
Jill E. Allen, PharmD, BCPS
Drug Information Consultant
Pin Oak Associates
Salt Lake City, Utah

Priya Karkhanis, MS
Scientific Consultant
Hillsborough, New Jersey

Christine Sokoloski, MS
Scientific Consultant
Hillsborough, New Jersey

*Statements are the sole opinion of Dr. Fudin and do not reflect the opinion of employers, employee affiliates.

Faculty Disclosures
Jeffrey Fudin, PharmD, DAAPM, FCCP, FASHP, reports the following relevant commercial financial relationships in the past 12 months:
Consultant: AstraZeneca, Depomed, Kaléo Pharma, Millennium Health LLC, Zogenix
Speakers’ bureaus: AstraZeneca, Kaléo Pharma, Millennium Health LLC
Lecture fees: PainWeek and Pain Weekend

Bill McCarberg, MD, FABPM, reports the following relevant commercial financial relationships or affiliations in the past 12 months:
Consultant: AstraZeneca, Collegium, Depomed, Inspirion, Iroko, Janssen, Kaléo, Mallinckrodt, Millennium, Pfizer, Salix, Takeda, Zogenix
Board membership: American Academy of Pain Medicine, American Board of Pain Medicine
Stockholder: Biospecifics Technologies, Galena, Johnson & Johnson, Nektar Therapeutics, Protein Design Labs

James B. Ray, PharmD, CPE, reports the following relevant commercial financial relationships or affiliations in the past 12 months:
Consultant and honoraria: AstraZeneca, Mallinckrodt Pharmaceuticals
Lecture fees: PainWeek and Pain Weekend
Meeting/conference attendance: PainWeek
Stockholder: Alchemy Consulting, PC

Editorial Support Disclosures
Jill E. Allen, PharmD, BCPS; Priya Karkhanis, MS; and Christine Sokoloski, MS, have no relevant commercial financial relationships or affiliations to disclose.

The American Journal of Managed Care 
Publishing Staff—Jeff D. Prescott, PharmD, RPh; Ida Delmendo; and Cindy Spielvogel have no relevant financial relationships with commercial interests to disclose.

University of Cincinnati
Planning Staff—Susan P. Tyler, MEd, CMP, CCMEP, Director, University of Cincinnati, has nothing to disclose.

CME Physician Reviewer—Rick Ricer, MD, University of Cincinnati, has nothing to disclose.

Pharmacy Times Office of Continuing Professional Education
Planning staff—David Heckard; Maryjo Dixon, RPh; Donna Fausak; and Nathalie Harden have no relevant financial relationships with commercial interests to disclose.

Disclosure Policy
According to the disclosure policy of the University of Cincinnati, all persons who are in a position to control content are required to disclose any relevant financial relationships with commercial interests. If a conflict is identified, it is the responsibility of the University of Cincinnati and Pharmacy Times Office of Continuing Professional Education to initiate a mechanism to resolve the conflict(s). The existence of these relationships is not viewed as implying bias or decreasing the value of the activity. All educational materials are reviewed for fair balance, scientific objectivity of studies reported, and levels of evidence.

Disclosure of Unapproved/Off-Label Use
The contents of this activity may include information regarding the use of products that may be inconsistent with or outside the approved labeling for these products in the United States. Participants should note that the use of these products outside current approved labeling is considered experimental and are advised to consult prescribing information for these products.

The information provided in this CE/CME activity is for continuing medical and pharmacy education purposes only and is not meant to substitute for the independent medical or pharmacy judgment of a physician or pharmacist relative to diagnostic, treatment, or management options for a specific patient’s medical condition.

The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of The American Journal of Managed Care, Pharmacy Times Office of Continuing Professional Education, and the University of Cincinnati, or any of the companies that provided commercial support for this CE/CME activity.


Signed disclosures are on file at the office of The American Journal of Managed Care, Plainsboro, New Jersey.

Opinions expressed by authors, contributors, and advertisers are their own and not necessarily those of Clinical Care Targeted Communications, LLC, d/b/a Managed Care & Healthcare Communications, LLC, the editorial staff, or any member of the editorial advisory board. Clinical Care Targeted Communications, LLC, d/b/a Managed Care & Healthcare Communications, LLC, is not responsible for accuracy of dosages given in articles printed herein. The appearance of advertisements in this publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality, or safety. Clinical Care Targeted Communications, LLC, d/b/a Managed Care & Healthcare Communications, LLC, disclaims responsibility for any injury to persons or property resulting from any ideas or products referred to in the articles or advertisements.
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