• Center on Health Equity and Access
  • Clinical
  • Health Care Cost
  • Health Care Delivery
  • Insurance
  • Policy
  • Technology
  • Value-Based Care

GLP-1 Agonists With Insulin Yield Remarkable Results

Article

A meta-analysis published in The Lancet found that the combination was most successful in achieving the target A1C, with a minimal risk of hypoglycemia and weight loss.

hypoglycemia

New research published in The Lancet suggests that a combination of an injectable glucagonlike peptide-1 (GLP-1) agonist with basal insulin may be an excellent treatment option in patients with type 2 diabetes, resulting in robust blood glucose control with no increased or weight gain.

The combination offers great potential due to the complementary effects of the 2 agents, explain Conrad Eng, MSc, of the Leadership Sinai Centre for Diabetes, Toronto, Ontario, and colleagues in their paper published online September 12.

Senior author, Ravi Retnakaran, MD, also of the Leadership Sinai Centre for Diabetes, explained that there has been a "flurry of recent trials which have come out suddenly" studying combinations of these 2 therapies. He and his colleagues therefore decided to perform a meta-analysis. Of the 15 trials they included, the first few were conducted in 2011 but "9 or 10 are from 2014, and the majority from the past 3 months" he noted.

Read the complete report: http://bit.ly/1ByUFlb

Source: Medscape

Related Videos
Ian Neeland, MD
Chase D. Hendrickson, MD, MPH
Steven Coca, MD, MS, Icahn School of Medicine, Mount Sinai
Matthew Crowley, MD, MHS, associate professor of medicine, Duke University School of Medicine.
Susan Spratt, MD, senior medical director, Duke Population Health Management Office, associate professor of medicine, division of Endocrinology, Metabolism, and Nutrition,
Stephen Nicholls, MD, Monash University and Victorian Heart Hospital
Amal Agarwal, DO, MBA
Dr Robert Groves
Dr Robert Groves
Related Content
© 2024 MJH Life Sciences
AJMC®
All rights reserved.