Currently Viewing:
Newsroom
Currently Reading
ADA 2018 Standards Address Drugs With CV Benefits, Hold Firm on Blood Pressure
December 10, 2017 – Mary Caffrey
UC San Diego Researchers Receive $600,000 Grant to Test PI3Ky Inhibitor
December 08, 2017 – Kelly Davio
5 Approvals and Updates From the FDA This Week
December 08, 2017 – Jaime Rosenberg
AJMC® in the Press, December 8, 2017
December 08, 2017 – AJMC Staff
What We're Reading: Drug Imports; Insurers See ACA Profits; Alzheimer's Forecast
December 08, 2017 – AJMC Staff
This Week in Managed Care: December 8, 2017
December 08, 2017
Company Says It Will Seek FDA Approval for Video Game to Treat ADHD
December 07, 2017 – Allison Inserro
After Years of Research Into Dissatisfaction With Quality Measures, Is CMS Listening?
December 07, 2017 – Allison Inserro
Ribociclib Plus Oral Endocrine Partner Shows Efficacy in Women With HR+/HER2- Breast Cancer
December 07, 2017 – Jaime Rosenberg

Prescription Fills for High-Intensity Statins Increased from 2011 to 2014

Laura Joszt
From 2011 to 2014 the use of high-intensity statins following hospitalization for myocardial infarction (MI) increased progressively, according to a study published in Journal of the American College of Cardiology.
From 2011 to 2014 the use of high-intensity statins following hospitalization for myocardial infarction (MI) increased progressively, according to a study published in Journal of the American College of Cardiology.

Researchers examined trends and predictors of high-intensity statin use following hospital discharge for MI using the MarketScan database for commercial insurance and Medicare for government health insurance. The study included 42,893 MarketScan beneficiaries who were younger than age 65 and 75,096 Medicare beneficiaries between the ages of 66 and 75.

During the study period, the percentage of beneficiaries filling their first high-density statin prescription following hospital discharge of MI increased from 33/5% to 71/5% among the MarketScan group and from 24.8% to 57.5% for the Medicare group.

“Several events occurred during the study period that may have contributed to the changes in high-intensity statin use,” the authors determined.

First, the patent on the statin atorvastatin expired, and by mid-2012 there were less costly generic formulations of atorvastatin becoming available. Second, guidelines from the American Heart Association/American College of Cardiology recommended high-intensity statin use for patients younger than age 75 who had acute coronary syndrome.

The researchers determined that men, those filling beta-blocker and antiplatelet agent prescriptions within 30 days after discharge, and those attending cardiac rehabilitation were more likely to initiate a high-intensity statin versus a low- or moderate-intensity statin.

During this time, fills for atorvastatin increased, while fills for simvastatin or rosuvastatin decreased. The researchers explained that this likely happened because atorvastatin went off patent and because the FDA issued a black box warning against new prescriptions of simvastatin 80 mg because of potential muscle toxicity.

“Despite this favorable trend, a substantial percentage of patients filled low- or moderate-intensity statin prescriptions following hospital discharge for MI in 2014,” the authors wrote. “The present study highlights the need to continue efforts to increase high-intensity statin use following hospital discharge.”

 
Copyright AJMC 2006-2017 Clinical Care Targeted Communications Group, LLC. All Rights Reserved.
x
Welcome the the new and improved AJMC.com, the premier managed market network. Tell us about yourself so that we can serve you better.
Sign Up
×

Sign In

Not a member? Sign up now!