Donna Hansel, MD, PhD, of University of California, San Diego, School of Medicine, explains her use of human bladder cancer cells in her research.
Donna Hansel, MD, PhD, of University of California, San Diego, School of Medicine, explains her use of human bladder cancer cells in her research.
Transcript
A unique aspect of your lab is the use of human bladder specimens. Can you explain how you use them?
As a pathologist, we are often involved in dissecting specimens as they come out of the operating room. A lot of what we see when we open the bladder and also as we see it under the microscope really helps me at least formulate ideas about what’s happening with invasion and the spread of bladder cancer cells. What we try to do, especially because my lab studies invasion, is to say, "okay, well, we have all these wonderful in vitro techniques that we can use in the laboratory, but is there a way to use ex vivo techniques? Using actual human bladder cancer cells and using the background bladder matrix that the cells invade into?" Having done that, we’ve developed ex-plant models, primary culture models, things where we can take the cells and take the matrix that they invade into and modulate both of those to better understand how the interaction of cancer cells with the environment permits cancer growth.
Oncology Onward: A Conversation With Penn Medicine's Dr Justin Bekelman
December 19th 2023Justin Bekelman, MD, director of the Penn Center for Cancer Care Innovation, sat with our hosts Emeline Aviki, MD, MBA, and Stephen Schleicher, MD, MBA, for our final episode of 2023 to discuss the importance of collaboration between academic medicine and community oncology and testing innovative cancer care delivery in these settings.
Listen
The Pivotal Role of Payers in Improving Health Equity, Maternal Health Care in the US
March 26th 2024A presentation at the Greater Philadelphia Business Coalition on Health's 2024 Women’s Health Summit discussed how payers, including employers and public entities, can strategically influence health care purchasing to prioritize maternal health and equity.
Read More
The Importance of Examining and Preventing Atrial Fibrillation
August 29th 2023At this year’s American Society for Preventive Cardiology Congress on CVD Prevention, Emelia J. Benjamin, MD, ScM, delivered the Honorary Fellow Award Lecture, “The Imperative to Focus on the Prevention of Atrial Fibrillation,” as the recipient of this year’s Honorary Fellow of the American Society for Preventive Cardiology award.
Listen
Dupilumab Considered Safe, Effective Treatment for Adolescent, Adult Patients With AD
March 20th 2024These posters both used the GLOBOSTAD study, which demonstrated through patient and physician assessments that dupilumab is a safe and effective treatment for adolescent and adult patients with atopic dermatitis (AD).
Read More