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HHS Reissues Dsputed 340B Policy on Orphan-Drug Discounts
HHS issued an interpretive rule that requires drug companies to provide discounts on orphan drugs sold through a federal program just months after a judge struck down the government's previous version of the rule.
AJMC Study Finds Medicaid Barriers to the Right Drugs May Cause More with Schizophrenia to Land Behind Bars
A study in The American Journal of Managed Care finds Medicaid prior authorization requirements for newer antipsychotic drugs are associated with an increased likelihood that individuals with schizophrenia will be incarcerated for nonviolent drug offenses. The study comes amid media scrutiny over whether cutbacks in mental health actually save money, when other costs are taken into account.
IT, Patient-Centered Research Key to Pushing Disease Prevention Efforts
Information technology will be crucial to pushing disease prevention efforts in healthcare.
To Prevent Surprise Bills, New Health Law Rules Could Widen Insurer Networks
The Obama administration and state insurance regulators are developing stricter standards to address the concerns of consumers who say that many health plans under the Affordable Care Act have unduly limited their choices of doctors and hospitals, leaving them with unexpected medical bills.
Breakthrough Therapy Designation for Aduro's Immunooncology Combination for Pancreatic Cancer
Aduro joins the exclusive group of companies, so far only the big pharma, that have a successful trail of immunooncology candidates.
HPV Screen Better Predictor of Cervical Cancer Risk Than Pap Test
The researchers found that the risk of developing cervical cancer within three years following a negative HPV test result was about half of the already low risk following a negative Pap test.
Lawmakers Urge CMS to Extend MU Hardship Exception for Pathologists
Eighty-nine members of Congress have asked the Centers for Medicare & Medicaid Services to give pathologists a break and extend the hardship exemption they currently enjoy for all of Stage 3 of the Meaningful Use program.
Why Are Payers Concerned with Patient Engagement Strategies?
While healthcare organizations and providers are addressing strategies for engaging patient populations in the pursuit of incentive or value-based reimbursements, payers are actively looking for ways to engage this same population as consumers in the name of healthcare reform.
Personalized Medicine: It May be High Cost, but It’s Higher Value
Personalized medicine will be expensive in these early days of pioneering and planning. But individual genomic testing is not going to be exorbitant forever – and the ROI is gonna be big, both in patient outcomes and dollars saved.
In ACO Era, Physicians Will Still Play a Leading—But Changing—Role
More than 8 million Americans have signed up for health insurance thanks to the Patient Protection and Affordable Care Act. Significantly increasing access to care, the 4-year-old healthcare reform law also creates incentives for providers to reorganize the delivery of healthcare.
HCA Earnings Get Bigger Boost than Expected from Healthcare Reform
HCA, the country's largest for-profit hospital chain by revenue, Wednesday previewed strong second-quarter results, highlighting a 12.2% increase in income before taxes. It also raised its financial guidance for the year.
In the Literature: No Survival Advantage Following Mastectomy in Stage I or II BRCA-Negative Breast Cancer
Preventive mastectomy did not improve survival in the study population.
Kentucky Law Grants Prescribing Authority to Nurses
A new Kentucky state law that expands prescribing authority for advanced practice registered nurses took effect Tuesday, the same day that a study was published touting the benefits of having nurses manage care for patients with chronic conditions such as diabetes and high blood pressure.
Immunosignatures Could Replace Cancer Biomarkers in Early Diagnosis
The study, published in PNAS, showed that the peptide microarrays could classify complex heterogeneous cancers with upto 98% accuracy.
ACO Coalition Web Session: Despite Need, Challenges Confront Value-Based Healthcare
The ACO and Emerging Healthcare Delivery Coalition, an initiative of The American Journal of Managed Care, hosted a recent Web-based session that featured three presentations on aspects of the transition to value-based care: why barriers to change persist, what steps one ACO is taking to drive better health, and why a “patient-centered” method of picking a doctor makes sense.
Study at Northwestern Medicine Proves Efficacy of Tamoxifen Gel in Breast Cancer
The study, published in Clinical Cancer Research, showed that the gel could prevent growth of breast cancer, with fewer side effects.
Alarming Results: Androgen-Deprivation in Early-Stage Prostate Cancer Patients May Not Influence Long-Term Survival
The long-term study, published in JAMA Internal Medicine, was conducted in more than 65,000 men over the age of 66 years with early-stage prostate cancer.
Genentech's Avastin Granted Priority Review: Cervical Cancer
Genentech submitted the BLA for bevacizumab for the treatment of recurrent or metastatic cervical cancer.
Narrow Provider Networks Set to Spread
As the healthcare industry focuses on cutting costs, narrow provider networks designed to deliver value are taking hold as a widespread business practice.
Doctors' Employment Contracts Due For Renewal—and Revamp
Physician employment contracts with hospitals that were signed in the early days of healthcare reform are coming up for renewal Experts say the expectation of payment reform requires that these new deals include the flexibility to adapt to expected and unforseeable changes.
Literature: Method of Acquiring Tumor Samples Can Influence Proteomic Biomarkers
The authors sought to determine if tumor heterogeneity and biospecimen variables affect the evaluation of PI3K/Akt/mTOR pathway markers in breast cancer.
Type of Anesthesia May Influence Breast Cancer Recurrence Post-Surgery
In vitro studies demonstrated a reduced incidence of apoptosis in patients administered inhaled anesthetics compared with those administered propofol during surgery.
In the Literature: PD-L1 Overexpression Associated With Activating EGFR Mutation in NSCLC
High expression of PD-L1 was associated with the presence of EGFR mutations in surgically resected NSCLC and was an independent negative prognostic factor for this disease.
Hospitals, Regulators Spar Over In-Patient Care Policy
Fewer patients linger for days in hospitals without being admitted because of a new federal rule, but hospital and consumer groups are suing the government because they say the policy compromises Medicare patients' care, and patients are often stuck with costly, unexpected bills.