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ESMO 2014: Nivolumab Promise in Melanoma
Results from the CheckMate-037 trial showed a significant increase in duration of response in patients with advanced melanoma administered nivolumab as second- or third-line therapy
Medicaid Enrollees Have Difficulty Getting Access to Care
Medicaid enrollment under the Affordable Care Act grew even in states that chose not to expand eligibility, making access to care a more pressing issue, according to a new report issued by HHS’ Office of the Inspector General.
Costs Can Go Up Fast When ER Is in Network but the Doctors Are Not
Even the most basic visits with emergency room physicians and other doctors called in to consult are increasingly leaving patients with hefty bills: More and more, doctors who work in emergency rooms are private contractors who are out of network or do not accept any insurance plans.
Employers May Find Savings From ACOs, Journal Reports
The accountable care organization, or ACO, can be a mechanism for employers to achieve healthcare savings, according to a just-published article in The American Journal of Accountable Care, the publication of The American Journal of Managed Care dedicated to healthcare reform.
Xalkori to Treat ROS1-Mutated Lung Cancer Patients?
Xalkori, currently approved for treating NSCLC with ALK rearrangements, reduced the tumor size in nearly 75% of the patients and also extended the remission period.
Without Teens in Cancer Trials, Cure Rates Won’t Improve
Fictional teens with cancer may be suddenly popular in film and TV, but they are hard to find in the one place where they are most needed: in clinical trials to find drugs to save their lives. A story in the new issue of Evidence-Based Oncology, a publication of The American Journal of Managed Care, examines this problem.
Perjeta Improves Survival in HER2-Positive Breast Cancer Patients
The monoclonal antibody extended survival by nearly 16 months compared to those in the control cohort.
AJMC Review Offers Roadmap for Getting Paid in Molecular Diagnostics
Both Medicare and commercial insurers have raised the bar for molecular diagnostic companies, requiring them to show clinical utility to receive reimbursement for cellular tests designed to guide treatment in cancer, rheumatoid arthritis, and other diseases. An important new article in The American Journal of Managed Care reviews cases from a top Medicare contractor and outlines how to build the evidence to meet today’s standards.
HHS Grants $212 Million to Fight Chronic Diseases
Nearly $212 million in grant awards has been made available to all 50 states and the District of Columbia to support programs aimed at preventing chronic diseases, according to a recent announcement by HHS Secretary Sylvia M. Burwell.
Gilead's New Hep C Combination Backed by EMA
Harvoni, the sofosbuvir/ledipasvir combination, received accelerated assessment and will now be sent to the European Commission for EU-wide marketing authorization.
A New Drug Delivery Vehicle: Anthrax Bacteria
Having delivered antibody mimics to cancer cells in vitro, the research group at MIT that conducted the research is now working on evaluating the technique in tumors grown in mice.
UnitedHealthcare Established New ACOs in Illinois
UnitedHealthcare is establishing new accountable care organizations with Advocate Health Care and Illinois Health Partners that will provide coordinated care for more than 65,000 Illinois residents.
ICD-10 Readiness Varies Greatly Across Healthcare Industry
Healthcare providers have shown a lack of progress regarding ICD-10 readiness compared with a year ago, while vendors are mostly prepared, according to a new WEDI survey.
Hypercalcaemia as an Early Cancer Biomarker
A study published in the British Journal of Cancer discovered a correlation between hypercalcaemia and the risk of cancer, specifically in males.
ESMO Congress: Researchers Identify Barriers to Drug Access
The researchers identified discrepancies across the globe in patient access to life-saving cures for cancer.
American Journal of Managed Care’s ACO Coalition to Meet in Miami
The American Journal of Managed Care brings the next meeting of its ACO and Emerging Healthcare Delivery Coalition to the Miami Marriott Biscayne Bay October 16-17, 2014, where participants can learn and share best practices in an effort to improve overall patient outcomes.
HIT Interoperability Remains a Challenge for ACOs
Poor interoperability across health information technology systems is preventing accountable care organizations from using the technology to improve clinical quality.
Uninsured Rate Among Latinos Dropped Significantly in Medicaid Expansion States
The uninsured rate among Latinos dropped sharply under the Affordable Care Act, but there were stark differences between states that have expanded Medicaid and those that have not.
Treating Late-Stage Lung Cancer Not Cost-Effective: JTO Study
A prospective study published in The Journal of Thoracic Oncology found that the average cost to screen high-risk individuals for developing lung cancer with low-dose computed tomography plus the average cost of curative intent treatment, like surgery, is lower than the average cost to treat advanced stage lung cancer, which quite rarely results in a cure.
Lung Infections May Hamper Efficacy of FDG-PET
A new retrospective study published in JAMA identified that tuberculosis and certain fungal infections in the lungs could hamper the efficient detection of lung cancer by FDG-PET imaging.
As Open Enrollment Nears for 2015, Picture Emerges On First Year of Healthcare Coverage under ACA
For most of the spring, news on the Affordable Care Act was all about the numbers, and to much surprise enrollment surpassed the magical 7 million mark. Now, Patricia Salber, MD, and Christobel Selecky report in The American Journal of Accountable Care what having coverage means, whether it makes a difference, and what are the unanswered questions.
Hospitals’ Uncompensated Care Costs Will Decline $5.7 Billion
The Affordable Care Act will save hospitals a projected $5.7 billion in uncompensated care this year, according to a report released by HHS. Roughly three-quarters of those savings are coming from Medicaid expansion states.
NCI's New Approach With The Exceptional Responder Initiative
With the aim of understanding why some patients respond better to a particular drug, NCI has launched the Exceptional Responders Initiative, to generate molecular profiles of tumors that respond well to a particular treatment.
PAD2 Overexpression May Promote Skin Cancer
Research published this month in the journal Cancer Research, found that increased expression of the enzyme PAD2 in young mice could lead to skin tumors that could progress to invasive squamous cell carcinoma.
Eight Strategies to Drive Patient Engagement and Improve Healthcare Delivery
Patient experience and satisfaction is becoming an increasingly important aspect of providing healthcare, and a new roadmap outlines opportunities and key strategies to include patients and families in healthcare delivery.