From Diagnostics to Cancer Drug Costs, Nothing’s Off Limits at AJMCLive’s Patient-Centered Oncology Care
The toughest topics in cancer care will be on tap November 13-14, 2014, in Baltimore, Maryland, when AJMCLive presents Patient-Centered Oncology Care. If you’ve followed the discussion among pharmaceutical leaders, oncologists, and payers over access to care, you’ll want to join stakeholders to discuss how to ensure patients get what they need while controlling costs.
AMA Expresses Concerns Over ONC Departures
The American Medical Association voiced concerns over the fact that in addition to the departure of Karen. B. DeSalvo, MD, MPH, several other senior staff have recently left the Office of the National Coordinator for Health Information Technology.
Scheduled Steep Medicaid Cuts Put Access to Care at Risk
If the current payment parity program is allowed to expire at the end of the year, doctors will be forced to limit the number of new Medicaid patients they can afford to take on, according to 4 medical associations.
Simeprevir Responsible for Deaths in Japanese Hepatitis C Patients
A spike in the blood bilirubin levels resulting in hepatic dysfunction and/or renal impairment was determined as the cause of death.
CTFPHC: Do Not Use PSA to Screen for Prostate Cancer
The guideline, published in the Canadian Medical Association Journal, recommends against using PSA to screen for prostate cancer, pointing to the high risk of false positives and overdiagnosis.
Nanodevice to Help Titrate and Individualize Chemotherapy
A miniature device can measure a patient's blood for methotrexate, a commonly used but potentially toxic cancer drug.
Healthcare Price Transparency Decreases Costs Up to 14%
Calls for greater healthcare pricing transparency have been gaining steam. A new study in JAMA found use of a private price transparency platform was associated with lower claims payments for 3 common medical services.
Breast Cancer Risk Increased Following Chest Irradiation in Children
Radiation exposure due to chest irradiation in women who had childhood Wilms tumor increased their susceptibility to developing breast cancer later in life.
Merck's Rapid Strides With Pembrolizumab
Today, Merck announced that Keytruda has been granted breakthrough therapy designation for treating patients with epidermal growth factor receptor mutation-negative and anaplastic lymphoma kinase rearrangement-negative non-small cell lung cancer (NSCLC).
Scientists Identify a Novel Wnt Signaling Regulator in Colorectal and Endometrial Cancers
The gene mutation in RNF43, previously missed in The Cancer Genome Atlas study, was identified in 20% of colorectal and endometrial cancers.
Breakthrough Designation for Merck's Keytruda in NSCLC
Recently approved as second-line treatment of metastatic melanoma, following resistance to ipilimumab, the FDA has now designated Keytruda as breakthrough therapy to treat EGFR-mutation and ALK-rearrangement negative NSCLC patients who have pr0gressed following platinum-based therapy.
EHRs Increase Administrative Work for Physicians
Electronic health records could actually increase the physicians’ bureaucratic burdens, which already consume one-sixth of their time, according to a study by City University of New York professors.
Hospital Consolidation Is Increasing Patient Costs
Hospital consolidation for the purpose of improving patient care coordination and reducing cost of care is backfiring, according to a study published in the Journal of the American Medical Association.
VeriStrat Proteomic Test Approved by NCCN for Inclusion in NSCLC Treatment
NCCN recommended the diagnostic proteomic test to identify patients who can receive erlotinib as second-line therapy.
MIT Scientists Develop A Rapid Modeling Technique for Cancer Gene Mutations
The group, led by Koch Institute director Tyler Jacks, used CRISPR to generate mutant genes that were then packaged into enteroviruses that were used to infect target organs in mice. This is a much faster process than the traditional method that need crossing genetically-engineered mice.
Revelations of The Sunshine Act: $825 Million Spent by Pharma
A provision of the Affordable Care Act, the Sunshine Act provides for increased transparency in the healthcare realm.
New York City Doctor Has Tested Positive for Ebola
Craig Spencer, MD, an emergency medicine physician at New York Hospital/Columbia-Presbyterian was admitted to Bellevue Hospital Center in Manhattan where he has tested positive for Ebola.
Dr Karen B. DeSalvo Leaves ONC for Ebola Response Team
Effective immediately, Karen B. DeSalvo, MD, MPH, will be stepping down as national coordinator for health information technology to assist HHS in the fight against Ebola.
Evidence Shows Improved OS With Delayed Radiation Following Glioblastoma Surgery
The UCSF study identified a window of 30 to 35 days post surgery, following surgery in patients with glioblastoma multiforme, when delayed radiation significantly improved OS and PFS.
New Guiding Principles for Patient-Centered Care
Patient-centered care has been getting a lot of attention as the healthcare industry focuses on the Triple Aim of delivering better health outcomes, improving patient experience, and reducing the cost of care. In that vein, the Louis W. Sullivan Institute for Healthcare Innovation recently released 6 guiding principles of patient-centered care.
Financial, Clinical Outcomes for Hospitals Converting to For-Profit Status
Converting to for-profit status has a positive influence on a hospital’s finances, but no effect on quality or mortality rates, found researchers from the Harvard School of Public Health and Brigham and Women’s Hospital.
Collaborative Model Succeeds in Reducing Cancer Patient Readmissions
Oncologists and palliative care specialists at Duke University Hospital worked together in patient care, resulting in a 23% reduction in patient readmission within a week of discharge.
Hospitals’ Struggles to Beat Back Familiar Infections Began Before Ebola Arrived
While Ebola stokes public anxiety, more than 1 in six hospitals—including some top medical centers—are having trouble stamping out less exotic but sometimes deadly infections, federal records show.
In the Literature: A Speech Gene Prevents Breast Cancer Metastasis
The study, published in Cell Stem Cell, identified a microRNA-mediated inhibitory pathway that repressed expression of the speech and language gene FOXP2, promoting metastases of breast cancer cells to distant sites.
Plans Place Spending Caps to Reduce Costs
While reference pricing helps contain costs for insurers, it pits patients between the payer and provider.