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Inefficiencies in Osteoarthritis and Chronic Low Back Pain Management | Page 3

Published Online: October 23, 2013
Margaret K. Pasquale, PhD; Robert Dufour, PhD; Ashish V. Joshi, PhD; Andrew T. Reiners, MD; David Schaaf, MD; Jack Mardekian, PhD; George A. Andrews, MD, MBA, CPE; Nick C. Patel, PharmD, PhD, BCPP; and James Harnett, PharmD, MS
Among 22 prespecified measures of inefficiencies deemed to have clinical significance in the context of pain management, this study has elucidated inefficiencies accompanied by high per member and total pain-related cost. Specifically, excessive postsurgical opioid use ranked high in both categories.While associated costs of this measure included the costs of surgery, and therefore inflated the dollar amount, taking opioids beyond 90 days postsurgery is concerning from both the provider and payer perspectives. Alam and colleagues16 reported that among elderly patients undergoing low-risk surgeries, 8% who received an opioid for acute pain postoperatively at 7 days were still receiving an opioid 1 year later. Although 90 days of postoperative opioid use for an OA-related or back surgery may be clinically appropriate, strategies to limit transition from postoperative analgesia to long-term opioid use are warranted. These may include models of care that enhance coordination from the hospital to the community, administrative regulations on postsurgical opioid use, and drug utilization reviews.16

Within the opioid use category, concomitant long-acting opioid use ranked high in terms of per member cost, and uncoordinated opioid use ranked high in terms of total plan cost. Published data from 2 health plans reported a doubling of long-term opioid use between 1997 and 2005, reaching 4% to 5% among all enrolled adult members.17 This rise in opioid use has been accompanied by statistics indicating that inappropriate prescription, misuse, and abuse of opioids are widespread.4 dentifying members with excessive or uncoordinated opioid use could signal improper provider or patient behavior, or indicate that such members’ pain has not been controlled adequately.

Whereas repeated OA/LBP-related surgical procedures and nonsurgical inpatient admissions ranked highest by per member costs, inefficiencies in the outpatient setting (repeated diagnostic testing and excessive office visits) were the top cost drivers by total plan costs. Similar to excessive postoperative opioid use, care coordination techniques could curtail the prevalence of these  inefficiencies. For example, as integrated electronic medical records become commonplace, it may be possible to reduce the  duplication of the same diagnostic tests performed by different providers.

As for the outpatient inefficiency measure related to excessive office visits, these may or may not signal the inefficient management of pain, which is a limitation of this inefficiency measure. That is, excessive office visits may in fact be a less expensive way of  preventing more costly, inappropriate surgical procedures. In the case of CLBP, studies have questioned the benefit of surgical  stabilization of the lumbar spine over intense rehabilitation for CLBP18,19 and generated evidence for the high failure rate of back surgeries.20 Given the high costs of treatment for patients with failed back surgery,21 investing up front to pinpoint the etiology of the pain is of utmost importance  to identify appropriate candidates for surgery.22

In addition, the fact that repeated surgical procedures and inpatient admissions do not rank high from the point of view of total costs may be an indication that a thorough review of such members is already in place. However, close monitoring of CLBP patients with repeated office visits and/or diagnostic tests may help contribute to the evidence base for best practices, as well as to help  eliminate those practices associated with poorer outcomes. As with office visits, other inefficiency measures may signal the severity of the pain condition or the existence of more than 1 pain type (eg, concurrent adjuvant therapies). Although it is not possible to draw immediate conclusions about members identified with any of these other inefficiency measures, investigation is warranted to determine whether providers’ and patients’ behaviors are justified.

One limitation of the study is the appropriateness of the comparator group. Although it may be possible to define a narrower comparator group for each of the drug-related inefficiencies, this would not be possible for medical service utilization measures such as emergency department visits. Future work focused on 1 specific inefficiency measure could further examine the appropriateness of the comparator group. An additional limitation of the study is that high-cost outliers, commonly found in administrative claims data, are known to skew the cost data. Rather than attempting to remove the outliers, our approach was to report the median and standard devian tions alongside the mean costs to provide the reader with the degree of uncertainty in the data. Other limitations include lack of certain data (lab results, patient behavior) and error in claims coding (misclassification bias). Additionally, data were generated from 1 health plan, which implies that results are not generalizable to the general US population. However, members reside in a broad array of geographic US regions.

CONCLUSIONS

This study is the first to examine the prevalence of inefficiencies in pain management among Humana Medicare members with OA and/or CLBP and to rank healthcare costs associated with these inefficiencies. Inefficiencies in pain management are common and are associated with higher healthcare expenditures. These findings call for further work by providers and payers to determine the benefits of member identification and early intervention for these inefficiencies.

Take-Away Points

This study demonstrates that most Medicare members with osteoarthritis or chronic low back pain experience inefficient pain management. High-cost inefficiencies need to be further explored to determine benefits of identifying members experiencing pain and providing early intervention.
  • High per member costs were observed with repeated surgical procedures and inpatient admissions related to osteoarthritis or low back pain. High total costs (prevalence multiplied by per member cost) were observed for repeated diagnostic testing and excessive office visits.
  • Members with 1 or more inefficiencies had adjusted pain-related healthcare costs that were 5.42 times those of members without inefficiencies (P <.0001).
Author Affiliations: From Comprehensive Health Insights, Inc (MKP, RD, NCP), Louisville, KY; Pfizer Inc (AVJ, DS, JM, JH), New York, NY; Humana Inc (ATR, GAA), Indianapolis, IN.

Funding Source: This study was funded jointly by Pfizer Inc and Humana Inc.

Author Disclosures: Drs Pasquale, Dufour, and Patel report employment with Comprehensive Health Insights, Inc, a wholly owned subsidiary of Humana Inc, who were paid consultants to Pfizer in connection with the development of the manuscript. Drs Andrews and Reiners report employment with Humana Inc. Drs Schaaf, Mardekian, and Harnett report employment with Pfizer Inc, and have stock ownership in the company. Dr Joshi was a full-time employee of Pfizer Inc at the time of study and drafting of the manuscript, and also has stock ownership in Pfizer Inc.

Authorship Information: Concept and design (MKP, RD, AVJ, ATR, DS, JM, GAA, NCP, JH); acquisition of data (RD); analysis and interpretation of data (MKP, RD, AVJ, ATR, DS, JM, GAA, NCP); drafting of the manuscript (MKP, RD, NCP); critical revision of the manuscript for important intellectual content (MKP, RD, AVJ, ATR, DS, GAA, NCP, JH); statistical analysis (RD, JM); obtaining  funding (AVJ, NCP, JH); administrative, technical, or logistic support (MKP, AVJ); and supervision (AVJ, GAA, NCP, JH).

Address correspondence to: Margaret K. Pasquale, PhD, Principal Researcher, Comprehensive Health Insights, Inc, 325 W Main St WFP6W, Louisville, KY 40202. E-mail: mpasquale@humana.com.
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Issue: October 2013
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