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Real-World Outcomes of Initiating Injectable Therapies in Type 2 Diabetes Patients
To date, there has been no real-world comparative data published on the initiation of injectable therapy with insulin glargine disposable pen (GLA-P) of glucagons-like peptide-1 agonist liraglutide (LIRA) among type 2 diabetes patients. On day 1 of the American Diabetes Association's 72nd Scientific Sessions in Philadelphia, PA, an abstract was released by Levin et al which provided data from this exact comparative analysis.
To date, there has been no real-world comparative data published on the initiation of injectable therapy with insulin glargine disposable pen (GLA-P) of glucagons-like peptide-1 agonist liraglutide (LIRA) among type 2 diabetes patients. On day 1 of the American Diabetes Association’s 72nd Scientific Sessions in Philadelphia, PA, an abstract was released by Levin et al which provided data from this exact comparative analysis.
Using the Integrated Health Care Information System’s national managed care claim database, Levin et al assessed 1-year clinical outcomes and plan-paid healthcare costs of T2DM patients failing oral antidiabetic drugs (OADs) and initiating LIRA or GLA-P.
The study was conducted among 336 matched patients that had a mean baseline age of 53 years. Researchers founds that there were no statistically significant differences between GLA-P and LIRA cohorts, A1C reduction from baseline, and percentage of patients achieving A1C <7% among those with follow-up A1C data available. Additionally, researchers reported that hypoglycemia-related event rates were low in both cohorts. However, GLA-P patients had significantly lower study drug costs ($1,198 vs $2,784; P <.001), which resulted in lower diabetes-related healthcare costs ($5,653 vs $7,976; P = .02).
Levn et al concluded that, “among T2DM patients who failed OADs and initiated injectable therapy, GLA-P may be a more cost effective option than LIRA with similar clinical outcomes yet lower diabetes care cost.
To read more about this study, please visit the American Diabetes Association’s website.
Award-Winning Poster Presentations From AMCP 2024
April 23rd 2024At the Academy of Managed Care Pharmacy (AMCP) 2024 annual meeting, multiple poster presentations concerned with health equity, data collection, glucagon-like peptide-1 agonists, and more were acknowledged for their originality, relevance, clarity, bias, and quality.
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The Importance of Examining and Preventing Atrial Fibrillation
August 29th 2023At this year’s American Society for Preventive Cardiology Congress on CVD Prevention, Emelia J. Benjamin, MD, ScM, delivered the Honorary Fellow Award Lecture, “The Imperative to Focus on the Prevention of Atrial Fibrillation,” as the recipient of this year’s Honorary Fellow of the American Society for Preventive Cardiology award.
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Standard Criteria for Loss of Ambulation Needed in DMD
April 19th 2024A recent study suggests the differences between ambulation definitions for patients with Duchenne muscular dystrophy (DMD) can impact the identification of ambulant vs nonambulant individuals, and standard criteria across settings are needed.
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Promoting Equity in Public Health: Policy, Investment, and Community Engagement Solutions
June 28th 2022On this episode of Managed Care Cast, we speak with Georges C. Benjamin, MD, executive director of the American Public Health Association, on the core takeaways of his keynote session at AHIP 2022 on public health policy and other solutions to promote equitable health and well-being.
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An Overview of Health Care and Pharmaceutical Trends, 2023-2024
April 19th 2024Douglas M. Long, BA, MBA, was featured as the keynote speaker on the closing day of The Academy of Managed Care Pharmacy 2024 annual meeting, with a session dedicated to surveying the health care and pharmaceutical trends of the last year.
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