Published Online: November 15, 2008
Pierre-Yves Cr??mieux, PhD; Henry Buchwald, MD, PhD; Scott A. Shikora, MD; Arindam Ghosh, PhD; Haixia Elaine Yang, PhD; and Marric Buessing, BA
TO THE EDITORS:
In the September 2008 issue of the Journal, Dr. Finkelstein and Dr. Brown wrote an editorial1 in response to our study on the return on investment (ROI) to bariatric surgery.2 We thank Drs. Finkelstein and Brown for their thoughtful comments and outline below our responses to their critiques.
First, and perhaps most importantly, we agree with Drs. Finkelstein and Brown that, in an ideal setting, the decision to cover bariatric surgery should be based on the health benefits associated with the surgery rather than the speed of cost recovery. As they correctly point out, the standard we apply to bariatric surgery (full ROI) is not applied to heart disease, cancer, or diabetes treatments. Instead, the costs of treatment, whether pharmacologic or surgical, are evaluated against the benefits to patients. Our stricter standard does not consider benefits to the patients in calculating the ROI; instead, we focused exclusively on the economic return to the payer. The reality is that such ROI calculations are employed by third-party payers to determine coverage, and that pointing out the positive ROI might help focus third-party payers on the clinical benefits of the intervention, which Drs. Finkelstein and Brown correctly point to as the appropriate standard to apply in coverage decisions.
The editorial raises 3 methodological critiques. First, it questions the robustness of our findings because of limited long-term postoperative data, especially for laparoscopic patients. Second, the editorial observed that the cost savings could be the result of the worsening health of the control group rather than the improved health of the surgery patients. Finally, the editorial argues that a few patients with catastrophic outcomes could overturn our results.
We are fully confident that the results reported in our study are robust. We have tested the robustness of our findings by estimating alternative forms of models, including a 2-part model, alternative controls for comorbidities, additional and alternative time-related controls, alternative statistical corrections for standard errors, and multivariate analyses that omit matching but control for all 18 comorbidities and baseline costs directly in the model. All these robustness analyses yield results that fall within the range of ROIs reported in our analysis. In addition, since the publication of our article, we have received a significant update to our claims database, resulting in an additional 1200 surgery patients and an additional year (2006) of study data. This extends our postoperative data to 2.5 years for laparoscopic procedures and 7 years for open procedures. The resulting ROI was 29 months for laparoscopic surgery and 44 months for open surgery, well within the range of values reported in our paper. Based on these supplementary analyses, we believe that our results are robust.
Our data were limited to a few years even though patients may live 30 years postsurgery. Therefore, our study did not address the long-run uncertainty (beyond 7 years) of surgery cost savings. Of course, this is equally true for the control population. As was pointed out by Drs. Finkelstein and Brown, the morbidly obese control population is getting sicker and more expensive to treat relative to the surgery population as time elapses. These trends are likely to endure beyond the observed period as well.
Drs. Finkelstein and Brown comment that cost savings result from an increase in costs among the control group rather than a cost decrease among surgery patients. Although part of the cost gap between the surgery group and the control group resulted from increased costs for nonsurgery patients, costs for surgery patients do fall relative to presurgery costs. This finding demonstrates that bariatric surgery improves patient conditions and lowers costs both relative to presurgery conditions and to the morbidly obese control population.
Finally, we do not believe that a few patients with catastrophic outcomes could overturn the results. Our analysis included all medical costs, including any costs associated with complications or catastrophic outcomes on both sides. Furthermore, our sample size was large. Our published analysis is based on a sample of more than 3600 surgery patients and their controls, and our updated sample includes more than 4800 surgery patients and their controls. No single patient or single set of catastrophic outcomes for a patient will significantly affect our results given the size of the sample.
Pierre-Yves Crémieux, PhD
Arindam Ghosh, PhD
Haixia Elaine Yang, PhD
Marric Buessing, BA
Analysis Group, Inc
Henry Buchwald, MD, PhD
Department of Surgery
University of Minnesota
Scott A. Shikora, MD
Department of Surgery
Tufts-New England Medical Center
Author Disclosure: Drs Crémieux, Ghosh, and Yang and Ms Buessing report that their employer, Analysis Group, Inc, received an unrestricted educational grant from Ethicon Endo-Surgery, Inc for the preparation of the original manuscript. Dr Buchwald reports receiving grants from Ethicon Endo-Surgery, Inc and serving as a consultant and as the chair of their scientific advisory board. His involvement with the manuscript can be considered as payment from Ethicon Endo-Surgery, Inc. Dr Buchwald also consults for Fulfillium, Inc in return for stock ownership and consults for EnteroMedics. Dr Shikora reports receiving honoraria for speaking engagements, consultancies, and advisory board activities and owns stock in a number of companies within the healthcare sector, including Ethicon Endo-Surgery, Inc, EnteroMedics, Synovis, BariMD, GI Dynamics, Coviden, and others.
Address correspondence to: Pierre-Yves Crémieux, PhD, Analysis Group, Inc, 111 Huntington Ave, 10th Fl, Boston, MA 02199. E-mail: firstname.lastname@example.org.
1. Finkelstein EA, Brown DS. Return on investment for bariatric surgery. Am J Manag Care. 2008;14(9):561-562.
2. Crémieux PY, Buchwald H, Shikora SA, Ghosh A, Yang HE, Buessing M. A study on the economic effects of bariatric surgery. Am J Manag Care. 2008;14(9):589-596.