Improved Detection of Metastasized Prostate Cancer with a New Tracer

A study conducted at the Johns Hopkins University demonstrates improved detection of prostate cancer metastasis following the injection of 18F-DCFBC, which binds PSMA.
Published Online: June 11, 2014

A new radiotracing agent injected before PET/CT might improve the detection of metastasized prostate cancer, compared with conventional imaging, in patients with castration-resistant disease, according to preliminary results from a new study.

The agent, known as 18F-DCFBC, binds to prostate-specific membrane antigen (PSMA), a protein that is "highly expressed in prostate cancer, allowing for optimal signal detection," senior author Steve Cho, MD, PhD, from Johns Hopkins University School of Medicine in Baltimore, Maryland, told Medscape Medical News.

His group previously showed, in a first-in-human trial, that the tracer could detect sites of metastatic prostate cancer (J Nucl Med2012;53:1883-1891).

Original report: http://bit.ly/1s5rW6f

Source: Medscape



Feature
Recommended Articles
Approximately 70% of all Medicaid beneficiaries receive their healthcare services through managed care, and state Medicaid programs are required to report encounter data to a national database, but 8 states did not during fiscal year 2011, according to a new government report.
ICLIO promises to guide oncologists in community care practices to navigate the growing field of immuno-oncology.
The report found that Medicare Part B spending per beneficiary in 340B hospitals was more than twice that of hospitals outside the program. Groups such as the Community Oncology Alliance have long warned that the 340B program, while essential, has grown beyond its original intent.
Bruce Feinberg, DO; Scott Gottlieb, MD; and Ted Okon, MBA, discuss the recent establishment of the Oncology Care Model by the CMS and compare its structure with the Community Oncology Alliance’s Oncology Medical Home model.
During this segment, the managed care stakeholders discuss drug spending in oncology and its relation to the overall cost of cancer care. Additionally, they consider which stakeholders should work with pharmaceutical companies during the early stages of drug development, and to what degree stakeholders should collaborate with pharma.