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New research shows patients commonly take lower doses of nintedanib, and the majority are also taking immunomodulatory drugs.

Elevated levels of a combined biomarker integrating CRP, triglycerides, and glucose are associated with increased risk of rheumatoid arthritis.

In real-world usage, 97% of cases of cytokine release syndrome following treatment with lisocabtagene maraleucel happened within 15 days of infusion.

Pretransplant NPM1 MRD testing significantly predicts relapse risk in acute myeloid leukemia.

ATTRibute-CM data show acoramidis reduced mortality in ATTRwt-CM and ATTRv-CM and raised serum transthyretin through 42 months.

Over 50% of patients with high-grade serous ovarian cancer (HGSOC) had surgery, often decades before diagnosis, where salpingectomy could have reduced risk.

Phase 3 OCEANIC-STROKE data show how asundexian offers a potential new secondary stroke prevention option.

KYV-101 shows promising efficacy in treating generalized myasthenia gravis, achieving significant symptom reduction and demonstrating a novel CAR T-cell approach.

Altered expression across multiple ncRNA classes consistently correlates with inferior OS, PFS, and TTT in nearly 5000 patients.

A study reveals a U-shaped relationship between BMI and CAR T-cell therapy outcomes in multiple myeloma (MM), highlighting the impact of overweight status on efficacy.

TAM receptors could emerge as promising therapeutic targets for rheumatoid arthritis, offering insights into immune regulation and potential treatment strategies.

Higher CONUT nutritional scores strongly predict poorer survival and greater lung function decline in PPF, highlighting malnutrition as a key modifiable risk factor.

Levels of GDF15 and OPN can accurately distinguish uterine sarcoma from benign leiomyoma, with GDF15 also serving as an independent predictor of disease progression.

The algorithm could outperform existing noninvasive tools for identifying advanced fibrosis in MASH without producing indeterminate results.

Patients achieve a high 2-year survival and deep MRD-negative remissions with CAR T-cell therapy followed by stem cell transplant in B-cell ALL.

Long-term data suggest stress echocardiography can uncover impaired exercise capacity and predict worse outcomes in patients.

Shared savings reflects continued growth of long-term-care ACOs in Medicare’s value-based models.

Mirvetuximab soravtansine, particularly in combination regimens, showed promising efficacy and an acceptable safety profile in recurrent ovarian cancer.

The HIV chatbot was noninferior in increasing self-testing compared with the real-time support by human administrators.

Patients with elevated levels of multiple adipokines had the highest risk, the authors found.

New research comparing the safety profiles of the 2 multiple sclerosis therapies suggests ocrelizumab is associated with lower rates of all-cause hospitalization and hypogammaglobulinemia.

Combining genetic features with clinical data improved the performance of a pulmonary fibrosis prediction score for people with rheumatoid arthritis.

Pigment epithelial detachment and hyperreflective foci had better early control in age-related macular degeneration (AMD) when treated with faricimab.

New research reveals ritlecitinib's potential to reverse scarring alopecias by targeting inflammation, offering hope for hair regrowth in autoimmune disorders.

Telehealth has quickly become a central part of the mental health system among younger, higher-income, college-educated, and privately insured patients.

Sibeprenlimab gains accelerated approval from the FDA for IgA nephropathy, showing significant proteinuria reduction and offering convenient self-injection treatment.

After 8 months of treatment with mavacamten, 5% of patients developed new atrial fibrillation or flutter and 4% developed heart failure.

The expansion of direct-to-consumer (DTC) pharmaceutical manufacturer models and the upcoming TrumpRx launch offer lower costs but create new complexities for patients.