Donna Hansel, MD, PhD, of University of California, San Diego, School of Medicine, explains her use of human bladder cancer cells in her research.
Donna Hansel, MD, PhD, of University of California, San Diego, School of Medicine, explains her use of human bladder cancer cells in her research.
Transcript
A unique aspect of your lab is the use of human bladder specimens. Can you explain how you use them?
As a pathologist, we are often involved in dissecting specimens as they come out of the operating room. A lot of what we see when we open the bladder and also as we see it under the microscope really helps me at least formulate ideas about what’s happening with invasion and the spread of bladder cancer cells. What we try to do, especially because my lab studies invasion, is to say, "okay, well, we have all these wonderful in vitro techniques that we can use in the laboratory, but is there a way to use ex vivo techniques? Using actual human bladder cancer cells and using the background bladder matrix that the cells invade into?" Having done that, we’ve developed ex-plant models, primary culture models, things where we can take the cells and take the matrix that they invade into and modulate both of those to better understand how the interaction of cancer cells with the environment permits cancer growth.
Examining Low-Value Cancer Care Trends Amidst the COVID-19 Pandemic
April 25th 2024On this episode of Managed Care Cast, we're talking with the authors of a study published in the April 2024 issue of The American Journal of Managed Care® about their findings on the rates of low-value cancer care services throughout the COVID-19 pandemic.
Listen
Oncology Onward: A Conversation With Penn Medicine's Dr Justin Bekelman
December 19th 2023Justin Bekelman, MD, director of the Penn Center for Cancer Care Innovation, sat with our hosts Emeline Aviki, MD, MBA, and Stephen Schleicher, MD, MBA, for our final episode of 2023 to discuss the importance of collaboration between academic medicine and community oncology and testing innovative cancer care delivery in these settings.
Listen
Specialty Pharmacists at the Forefront: Elevating Care for Rare Diseases
May 1st 2024In the US, a disease is considered rare when it affects fewer than 200,000 persons, or 1 in every 1500 individuals, with an estimated total of 25 to 30 million Americans overall living with a rare disease at any given time.
Read More
Latest Advances and Updates of Treatment in the Real World at AUA
May 1st 2024The annual meeting of the American Urological Association (AUA) not only presents the newest therapies coming out but showcases the latest in how treatments are being used in the real world, said Stephen Freedland, MD, of Cedars Sinai.
Read More