- Center on Health Equity and Access
- Clinical
- Health Care Cost
- Health Care Delivery
- Insurance
- Policy
- Technology
- Value-Based Care
Dr Peter Hillmen Outlines Zanubrutinib as a New Option to Treat in R/R CLL
Ibrutinib is currently a standard of care in relapsed/refractory chronic lymphocytic leukemia, but zanubrutinib is an effective second-line and second-generation option, said Peter Hillmen, PhD, MB ChB, professor at the University of Leeds.
Ibrutinib is currently a standard of care in relapsed/refractory chronic lymphocytic leukemia, but zanubrutinib is an effective second-line and second-generation option, said Peter Hillmen, PhD, MB ChB, professor at the University of Leeds and honorary consultant hematologist at Leeds Teaching Hospitals NHS Trust.
Transcript
Ibrutinib is a standard of care in chronic lymphocytic leukemia. How can zanubrutinib differentiate itself as a treatment of choice?
So, I think ibrutinib is one of the standards of care, for sure, and we have a lot of mature data for ibrutinib in relapsed disease. So, it continues to be important treatment. I think we need more data and larger trials of safety for ibrutinib going forward, to look at those rare complications we see with BTK [Bruton tyrosine kinase] inhibition.
I think the zanubrutinib is an effective second-line, also second-generation, BTK inhibitor, and where available, you know, may say displace ibrutinib in some patient groups, I think. It's given twice a day, which is slightly less convenient, but most patients are fine. It can cause a little bit more neutropenia but doesn't seem to cause more infection. So, it's been, it's very well tolerated. I think it gives us more options with the number of BTK inhibitors is coming through.
Enhancing Outpatient Hemophilia Care May Improve Health Outcomes and Costs
May 18th 2024Prospective data from patients attending a rural practice in West Virginia between 2016 and 2023 show that a quality improvement program that followed guideline recommendations and was tailored to specific patient needs reduced preventable bleeds and lowered costs.
Read More
Frameworks for Advancing Health Equity: Urban Health Outreach
May 9th 2024In the series debut episode of "Frameworks for Advancing Health Equity," Mary Sligh, CRNP, and Chelsea Chappars, of Allegheny Health Network, explain how the Urban Health Outreach program aims to improve health equity for individuals experiencing homelessness.
Listen
Tackling Health Inequality: The Power of Education and Experience
April 30th 2024To help celebrate and recognize National Minority Health Month, we are bringing you a special month-long podcast series with our Strategic Alliance Partner, UPMC Health Plan. Welcome to our final episode of this limited series and our conversation with Janine Jelks-Seale, MSPPM, director of health equity at UPMC Health Plan.
Listen
