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Dr Roxana Siles: Blinded Trials Are Important When Evaluating Chronic Cough Treatment
Roxana Siles, MD, FAAAAI, staff in the Department of Allergy and Immunology at Cleveland Clinic and codirector of the Asthma Center at Cleveland Clinic, addresses the placebo effect seen in clinical trials of chronic cough treatment.
Roxana Siles, MD, FAAAAI, staff in the Department of Allergy and Immunology at Cleveland Clinic and codirector of the Asthma Center at Cleveland Clinic, addresses why a placebo effect is often seen in clinical trials investigating the impact of chronic cough treatment and how this is addressed.
Transcript
How might the placebo effect impact in clinical trials for chronic cough treatment be overcome when testing a medication’s effectiveness?
The placebo effect is real, and it’s not uncommon for patients who enter clinical trials for treatment of cough that they go through rigorous evaluation and they really maximize the therapy. One thing that’s common in trials is that patients tend to be perhaps more adherent to the regimen because they are in trials and perhaps they’re being monitored more closely. So yes, it can be tricky. But certainly, this is why we have blinded, placebo-controlled [trials], because they will tell us whether or not an effective treatment despite having that placebo benefit is even that much more effective when it comes to statistical data and finding that it is a good comparison.
Frameworks for Advancing Health Equity: Urban Health Outreach
May 9th 2024In the series debut episode of "Frameworks for Advancing Health Equity," Mary Sligh, CRNP, and Chelsea Chappars, of Allegheny Health Network, explain how the Urban Health Outreach program aims to improve health equity for individuals experiencing homelessness.
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Tackling Health Inequality: The Power of Education and Experience
April 30th 2024To help celebrate and recognize National Minority Health Month, we are bringing you a special month-long podcast series with our Strategic Alliance Partner, UPMC Health Plan. Welcome to our final episode of this limited series and our conversation with Janine Jelks-Seale, MSPPM, director of health equity at UPMC Health Plan.
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Study Reveals Link Between Ovarian Cancer, Subsequent Dry Eye Disease Incidence
May 13th 2024Patients diagnosed with ovarian cancer (OC), particularly those older than 60 years or with a disease duration exceeding 5 years, had a higher incidence of subsequent dry eye disease (DED), suggesting a potential correlation between OC and DED.
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