An expert ophthalmologist discusses a medication which targets enzymes in the Demodex mite, given over a six-week course.
This is a video synopsis/summary of an Insights involving Neda Shamie, MD.
There is a recently FDA-approved treatment for Demodex blepharitis called Xdemvy (lotilaner ophthalmic solution 0.25%). Xdemvy targets and paralyzes an enzyme only found in the Demodexmite, effectively eradicating the mite. It is used twice daily for 6 weeks to cover the full life cycle. Over the treatment course, thedrug shows an impressively effective response in not just controlling but eradicating Demodexinfestation. It is a fast, highly effective, and reliable treatment.
In studies and clinical practice, Xdemvy eyedrops have not had significant adverse effects. Most patients find it soothing to the ocular surface with no adverse reactions. About 10% of study patients described a burning sensation upon drop installation. Less than 2% developed chalazion or hordeolum while on treatment. Overallit is very safe, highly effective and welltolerated, with a 6-week, twice-daily course, which supports good compliance. Many patients report completing the full course, motivated to control their disease.
Video synopsis is AI-generated and reviewed by AJMC® editorial staff.
Perioperative Nivolumab Boosts NSCLC Survival: CheckMate 77T Trial
May 16th 2024This interim analysis of the CheckMate 77T trial, outcomes were compared between adult patients receiving neoadjuvant nivolumab plus chemotherapy or neoadjuvant chemotherapy plus placebo for resectable non–small cell lung cancer (NSCLC).
Read More
Frameworks for Advancing Health Equity: Urban Health Outreach
May 9th 2024In the series debut episode of "Frameworks for Advancing Health Equity," Mary Sligh, CRNP, and Chelsea Chappars, of Allegheny Health Network, explain how the Urban Health Outreach program aims to improve health equity for individuals experiencing homelessness.
Listen