Currently Viewing:
Newsroom
Currently Reading
Insomnia Correlated to an Increased Risk of Heart Disease and Stroke, Study Shows
August 19, 2019 – Matthew Gavidia
Inspiratory Muscle Training May Be an Option for Patients Who Decline Pulmonary Rehabilitation for COPD
August 18, 2019 – Kelly Davio
Blood Clots in MPN Related to Higher Cost, Length of Stay for Patients With MPN
August 17, 2019 – AJMC Staff
Researchers Seek to Determine Genetic Variability in Parkinson Progression
August 17, 2019 – AJMC Staff
FDA Panel Backs Use of Descovy for HIV Prevention in Men, Transgender Women
August 16, 2019 – Jaime Rosenberg
Researcher Excited About Future of Psoriasis Treatment
August 16, 2019 – Allison Inserro
This Week in Managed Care: August 16, 2019
August 16, 2019
AJMC® in the Press, August 16, 2019
August 16, 2019 – AJMC Staff
Pediatric Leukemia Treatment Linked to Increased Risk of Infections, Study Finds
August 16, 2019 – Alison Rodriguez

A Diet Rich in Fruit and Vegetables Could Help Improve Multiple Sclerosis Fatigue

Sara Karlovitch
A new study suggests lipid profiles could help improve multiple sclerosis (MS) fatigue.
A diet rich in fruits, vegetables, and fats, while being low in carbohydrates, can help improve fatigue in patients with progressive multiple sclerosis (MS), according to a study published in PLOS One.

Investigators found that lipid profile variables were associated with fatigue improvements in patients with progressive MS. Previous research on the same diet found that it is also associated with improved balance, walking, and quality of life. Investigators also saw improvements to body mass index (BMI) over the 12-month study period. 

The study included 18 patients with progressive MS. Of the 18 patients, 16 had secondary progressive MS while 2 had primary progressive MS. Out of the 18 patients, 12 were not on any disease-modifying treatments while 6 were. Participants were recommended 3 serving of leafy green vegetables daily and plenty of plant and animal protein was encouraged. Participants were only allowed 2 servings of gluten free grain or starchy foods weekly. Patients were also recommended dietary supplements that were thought to be beneficial to MS fatigue, but could stop taking them at any time. Fatigue was measured using the Fatigue Severity Scale. No control group was used.

Participants were also put on a personal home exercise plan that strengthened leg and trunk muscles. The routine also included stretching. Participants logged their diet and exercise in a journal. Weight loss was not a goal of the study; the study team was notified if any participant lost more than 10% of their body weight, and the participant would then be put on a higher calorie diet.   

Investigators found that changes in BMI were not associated with fatigue level. All dietary changes the participants made were in line with recommendations from the Dietary Guidelines for Americans.

“The results from this pilot study of the diet-based multimodal intervention are consistent with the possibility that lipid profile biomarkers, particularly [total cholesterol] and [high-density lipoprotein cholesterol], may contribute to improvement in MS fatigue” the authors wrote. “Our results require confirmation given the limitations of the current pilot study design, which include the small sample size, lack of control group and randomization. However, if confirmed in larger studies, lipid monitoring may become useful for guiding fatigue treatment decisions.”   

Reference

Fellows Maxwell K, Wahls T, Browne RW, et al. Lipid profile is associated with decreased fatigue in individuals with progressive multiple sclerosis following a diet-based intervention: Results from a pilot study. PLoS One. 2019;14(6):e0218075. doi: 10.1371/journal.pone.0218075.

 
Copyright AJMC 2006-2019 Clinical Care Targeted Communications Group, LLC. All Rights Reserved.
x
Welcome the the new and improved AJMC.com, the premier managed market network. Tell us about yourself so that we can serve you better.
Sign Up