Heart Failure

The AJMC® Heart Failure compendium is a comprehensive resource for clinical news and expert insights for the chronic condition in which the heart doesn't pump enough blood due to damaged heart muscle.

Superior Clinical Outcomes Seen in HFrEF With Early Initiation of Sacubitril/Valsartan

May 16th 2022, 10:25am


Two periods of sacubitril/valsartan initiation were compared in a study population of patients with heart failure with reduced ejection fraction (HFrEF): less than 3 months or 3 or more months following first HFrEF diagnosis.

Investigation Links Infertility to HF Risk Among Women

May 13th 2022, 4:33pm


Infertility as a predisposing factor for heart failure (HF) was the subject of this new study evaluating outcomes among postmenopausal women.

Remote Monitoring Not Successful at Reducing Death, Readmission From HF

May 9th 2022, 3:00pm


In this study, investigators from Pennsylvania and New York evaluated outcomes among patients following their hospitalization for heart failure (HF) who did or did not participate in a remote monitoring program that included financial incentives for adherence.

Cardiac Rehab Linked to Improved Mortality Among Patients With HFrEF

May 6th 2022, 10:31pm


In this study, outcomes were investigated among a cohort of patients with heart failure with reduced ejection fraction (HFrEF) who participated in a cardiac rehabilitation program post hospital discharge after they survived acute onset of HFrEF.

Study Calls for Sex-Specific Tactics to Reduce Rising Heart Attacks in Young Adults

May 3rd 2022, 3:00pm


These investigators wanted to better understand the reasons for the increased risk for acute myocardial infarctions among young women, who have the largest increase in hospitalization for heart attacks.

NT-proBNP Level May Influence HF Risk Among Blacks vs Whites, Men vs Women

April 27th 2022, 3:00pm


In this new subanalysis of data from the Atherosclerosis Risk in the Communities study, investigators assessed the risk of incident heart failure (HF) or death by race and sex, as influenced by N-terminal pro–B-type natriuretic peptide (NT-proBNP) concentration, prompted by growing interest in its use as a predictive biomarker for HF.

USPSTF Updates Preventive Aspirin Use Recommendation in CVD, CRC

April 26th 2022, 3:00pm


There may be a small, but not overwhelming, benefit for certain individuals aged 40 to 59 years who have a slightly elevated risk of future cardiovascular disease (CVD) to start taking aspirin, according to an update released by the US Preventive Services Task Force (USPSTF).

What We're Reading: Synthetic Nicotine Regulation; Philadelphia Mask Mandate Lawsuit; Hydration, Heart Failure Risk

April 18th 2022, 2:40pm


The FDA is increasing oversight of e-cigarettes and similar products that use synthetic nicotine; a lawsuit is brought over Philadelphia's reinstated mask mandate; a study shows drinking water may lower risk of heart failure.

Long-term Cardiac-Related Mortality Likely Predicted by 30-Day Postsurgical Outcomes

April 18th 2022, 11:56am


This study investigated long-term cardiac-related mortality as it relates to incidence of perioperative adverse cardiac events (excluding death) in the first 30 days after surgery among a short of patients who underwent non–cardiac-related surgery.

Machine Learning Can Identify Patients With HF at Risk for Wild-Type ATTR-CM Earlier

April 15th 2022, 12:53pm


Delayed diagnosis of wild-type transthyretin amyloid cardiomyopathy (ATTR-CM) results in inappropriate treatments prior to diagnosis and worse clinical outcomes after diagnosis.