Single-Count Breath Test Can Help Assess Respiratory Function in MG
A patient’s inability to count while holding their breath can be an indication of respiratory distress in myasthenia gravis.
Read More
Phase 3 Trials of Rozanolixizumab, Zilucoplan, Show Positive Results in Myasthenia Gravis
Results from 2 late-stage trials evaluating generalized myasthenia gravis therapies indicated both drugs, rozanolixizumab and zilucoplan, have potential as targeted treatment options.
MG Heightens Severe COVID-19 Risk, but Vaccination Helps Reduce Risk
People with myasthenia gravis (MG) had a higher risk of hospitalization for COVID-19 compared to the general population and a control group of people with rheumatoid arthritis (RA).
Refractory MG Presents Difficult Challenge for Patients, Clinicians
A new case series highlights characteristics and challenges of this subgroup of patients with myasthenia gravis (MG).
Case of Postoperative Heart Attack Demonstrates How MG Can Complicate Cardiac Procedures
A patient with myasthenia gravis (MG) quickly deteriorated after he woke up from an endovascular procedure.
New Insights Into Muscle-Specific Kinase Could Impact Myasthenia Gravis, Other Diseases
The new research could help identify ways to preserve neuromuscular junctions.
Age of Onset an Important Clinical Factor in Triple-Negative MG
Female patients were most likely to experience onset of triple-negative myasthenia gravis (MG) between ages 0 to 9 years.
Nomogram Developed to Predict Risk of Myasthenic Crisis Following Thymectomy
The tool can help clinicians stratify patients into high-risk and low-risk categories.
Case Report Shows Ocular MG, Autoimmune Encephalitis Can Coexist
The patient received a diagnosis of myasthenia gravis (MG), then underwent a medical odyssey as physicians attempted to pin down the cause of his neurological symptoms.
AChR Antibody Titers May Help Predict Conversion to Generalized Myasthenia Gravis
The new report suggests patients with acetylcholine receptor (AChR) antibody titers above 8.11 nmol/L were at higher risk of conversion.
Study: MuSK-Specific Antibodies Do Not Explain Variation in Serum IgG4 Levels in People With MuSK MG
People with muscle-specific kinase myasthenia gravis appear to have more active antibody responses in general, the study found.
German Study Finds a Third of Patients With Myasthenia Gravis Untreated After Diagnosis
The authors said it is the first study of epidemiology and real-world treatment in Germany.
Survey of Providers Indicates Need for Improved Myasthenia Gravis Management
Myasthenia gravis affects about 60,000 individuals in the United States.
Case Report and Review Examines MG and COVID-19
Just 26 cases have been reported in which myasthenia gravis (MG) symptoms appeared following vaccination.
RNS Not a Meaningful Prognostic Tool in Myasthenia Gravis
While repetitive nerve stimulation (RNS) remains a mainstay of myasthenia gravis diagnosis, investigators said it does not appear to yield prognostic insights.
Inflammation Could Prove Meaningful Target in Myasthenia Gravis
The article suggests the inflammatory components of myasthenia gravis have been underexplored in the effort to develop new therapies.
Live Cell-Based Assays May Find Antibodies in Some Seronegative MG Cases
A different type of test may improve diagnosis for some patients with myasthenia gravis (MG).
Case Shows Difficulty of Diagnosing Myasthenia Gravis Following COVID-19
The patient, an 83-year-old man, experienced onset of myasthenia gravis after a severe SARS-CoV-2 infection.
Myasthenia Gravis Likely Leads to Significant Impact on QOL
Even patients with the mildest symptoms of myasthenia gravis said they experienced negative quality-of-life (QOL) effects from the disease.
Lower CTLA4 Levels May Indicate Risk of MG in Patients With Thymoma
The findings from among patients with myasthenia gravis (MG) could point the way to a potential new drug target, the authors said.
Ocular MG Should Be Considered in Patients With Ptosis, Diplopia, Says Study
With most previous studies on ocular myasthenia gravis stemming from investigations the neurology field, the present investigators came to their conclusion via neuro-ophthalmic analysis.
Clarifying the Factors in Myasthenia Gravis That Create Higher HCRU
A real-world study of health care resource utilization (HCRU) in patients with myasthenia gravis on second-line therapy identified the factors that led to increased financial burdens.
Thymectomy Reduces Hospital Stay From Myasthenia Gravis With Acute Exacerbation
The researchers note that this finding adds valuable insight for individualized treatment decisions in scenarios where the role of thymectomy is not fully clear.
Rates of Depression, Anxiety Higher in MG Than in Other Autoimmune Diseases
The systemic review and meta-analysis, believe the researchers, is the first of its kind to characterize the prevalence of depression among these patients.
COVID-19 May Accelerate Onset of Myasthenia Gravis, Case Study Suggests
The researchers hypothesize that SARS-CoV-2 infection may have triggered thymic inflammation, spearheading initial expression of muscle-like epitopes and T-cell dysregulation.
