The AJMC® Cholangiocarcinoma compendium is a comprehensive resource for clinical news and expert insights about this rare cancer of the bile duct.

Composite Quality Metric Can Help Predict Surgical Outcomes in ICC

September 26th 2022, 4:32pm


Only about 11% of patients received care meeting a composite quality metric, a study found.

Study Supports Comprehensive Genomic Profiling for Patients With Biliary Tract Cancer

September 24th 2022, 5:00pm


A small study suggests that comprehensive genomic profiling can help with clinical decision-making and predicting clinical outcomes in advanced biliary tract cancer, but further research is needed.

Case Report Describes Youngest Recorded Patient With Intrahepatic Sarcomatoid Cholangiocarcinoma

September 24th 2022, 3:00am


The rare condition can easily be confused with hepatocellular carcinoma, but immunohistochemical studies can help accurately diagnose intrahepatic sarcomatoid cholangiocarcinoma.

Many Patients With iCCA Still Do Not Get Curative Treatment

September 12th 2022, 11:00pm


About 4 in 10 patients do not receive curative therapy despite early detection, a new study shows.

Understanding Mechanisms, Strategies for Secondary IDH1-Inhibitor Resistance in IHCC

September 7th 2022, 5:45pm


The findings suggest that sequential mutant IDH inhibitor therapy might be one way to fight resistance in metastatic intrahepatic cholangiocarcinoma (IHCC).

Durvalumab With Chemo Wins FDA Approval in Treatment of Biliary Tract Cancers

September 6th 2022, 5:19pm


An estimated 1 in 4 patients treated with durvalumab and chemotherapy (gemcitabine plus cisplatin) was alive at 2 years compared with 1 in 10 treated with chemotherapy alone, with these results contributing to the FDA's approval of the first immunotherapy to treat these cancers.

Incidence, Outcomes of HCC in Louisiana Continue to Lag Behind Nation

September 6th 2022, 1:05pm


The increase in the incidence of hepatocellular carcinoma in Louisiana was nearly double that of the United States as a whole between 2005 and 2015.

Nestin May Help Diagnose, Risk-Stratify Patients With Rare Form of CCA

August 28th 2022, 10:45am


New research suggests Nestin expression can help distinguish combined hepatocellular-cholangiocarcinomas (CCAs) from hepatocellular carcinomas and intrahepatic cholangiocarcinomas.

Biliary Drainage Often Unsuccessful in Perihilar Cholangiocarcinoma

August 22nd 2022, 2:31pm


The procedure can be beneficial prior to chemotherapy, but it also has high rates of complications, this new analysis shows.

Biomarker Testing Increasingly Important, But Still Challenging, in iCCA

August 17th 2022, 12:15pm


A new report offers insights from a multidisciplinary team of experts on intrahepatic cholangiocarcinoma (iCCA).