Hematology

ACIP Votes to Lift Pause on J&J COVID-19 Vaccine

April 23rd 2021, 9:32pm

Article

The CDC's Advisory Committee on Immunization Practices voted to uphold the original language of the emergency use authorization for Johnson & Johnson's COVID-19 vaccination, and is possible the 1-dose vaccine could resume Saturday.

Gene Transfer Therapy Requires Further Investigation Despite Potential Approval, Review Says

April 23rd 2021, 8:17pm

Article

After a more than 35-year pursuit, the licensing of a gene therapy product for treating hemophilia may be available within 2 years.

Carfilzomib, Bortezomib Combo Shows Potential for Reducing Tumor Growth in Melanoma Cells

April 15th 2021, 3:45pm

Article

The in vitro study of melanoma cells analyzed the molecular mechanisms of the pair of proteasome inhibitors, finding that they reduced B16-F1 tumor growth.

CDC, FDA Call for Pause of J&J COVID-19 Vaccine After Safety Concerns Around Clotting

April 13th 2021, 3:18pm

Article

After cases of rare and severe blood clots led to 1 death and 1 hospitalization, the CDC and FDA will pause the use of Johnson & Johnson's (J&J) COVID-19 vaccine.

Bortezomib Appears to Increase Fall Risk in Elderly Patients With MM, Study Suggests

April 9th 2021, 11:45am

Article

Patients who experienced a fall within 12 months of multiple myeloma (MM) treatment initiation had a shorter median survival compared to those without falls.

Older Patients With MM Can Forgo Steroids in Treatment and See Similar Outcomes

April 4th 2021, 12:45pm

Article

The combination of lenalidomide with steroid dexamethasone is standard of care in multiple myeloma (MM), but new research shows older patients can be spared the steroids.

FDA Approves Isatuximab, Carfilzomib, Dexamethasone Combination for RRMM

April 3rd 2021, 9:30am

Article

Multiple myeloma is the second most common blood cancer, affecting more than 130,000 US patients.

The Impact of Sickle Cell Disease Severity on HRQOL and Economic Outcomes

April 1st 2021, 12:40pm

Article

Disease severity was strongly associated with health-related quality of life, moderately associated with use of disability insurance, and weakly associated with household income for patients with sickle cell disease.

Trial Analyzes Efficacy of Tailoring MM Treatment to MRD Response

March 25th 2021, 1:30pm

Article

Twice weekly high doses of carfilzomib in combination with lenalidomide and dexamethasone was tolerable and effective among patients with newly diagnosed multiple myeloma.

Many Options, Many Updates to NCCN Guidelines in Multiple Myeloma

March 24th 2021, 5:45pm

Article

Updates to the NCCN Guidelines in multiple myeloma reflect recent trial results, giving clinicians and patients many choices.