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Rose McNulty
Articles
Risk vs Impact: Viral Gene Therapy for SMA
September 26, 2021
Article
A recent review of viral gene therapy in pediatric neurological diseases included positive outcomes in patients with spinal muscular atrophy (SMA).
CDK4/6 Targeting May Be Effective in Acquired BRAF Plus MEK Inhibitor–Resistant Melanoma
September 25, 2021
Article
Combination CDK4/6 and MEK inhibitor treatment reduced tumor growth in mouse models of melanoma with acquired resistance to BRAF and MEK inhibition.
Trial Confirms Clinical Activity of Trametinib Plus Dabrafenib in BRAF-V600–Mutant Melanoma
September 24, 2021
Article
The largest known prospective study of patients treated with trametinib plus dabrafenib for unresectable advanced melanoma with BRAF-V600 mutation confirmed the combination’s clinical activity.
SMA Growth Patterns Differ From General Pediatric Percentiles
September 24, 2021
Article
Recent research identified spinal muscular atrophy (SMA)–specific growth percentiles, aiming to improve clinical management of the nutritional aspects of the disease.
BTK Inhibition in CLL: Successes and Challenges
September 19, 2021
Article
A review of current data identified areas of progress in Bruton tyrosine kinase (BTK) inhibition for patients with chronic lymphocytic leukemia (CLL).
Lack of Awareness, Screening Slows SMA Diagnosis in Infants
September 18, 2021
Article
A pair of surveys found that there are knowledge and practice gaps preventing earlier diagnoses of spinal muscular atrophy (SMA) in infants and toddlers.
Care Utilization, Costs Significantly Differ Between First-Line Metastatic Melanoma Treatments
September 17, 2021
Article
A study of patients given first-line metastatic melanoma treatment showed that utilization rates were highest in patients using ipilimumab-containing therapies.
Study Clarifies Prevalence and Incidence of SMA in Japan
September 16, 2021
Article
An epidemiological investigation of spinal muscular atrophy (SMA) in Japan provided clarity on the genetic condition’s prevalence and incidence in the country and highlighted the importance of newborn screening for SMA
AJMCtv Interviews: April 2021
April 27, 2021
Article
AJMC®TV interviews let you catch up on what’s new and important about changes in healthcare, with insights from key decision makers—from the clinician, to the health plan leader, to the regulator. When every minute in your day matters, AJMC®TV interviews keep you informed. Access the video clips at ajmc.com/interviews. These interviews have been edited lightly for clarity.