Rose is a freelance writer for The American Journal of Managed Care® (AJMC®), where she previously worked as an editor.
She has a BA in journalism & media studies and Spanish from Rutgers University. You can connect with Rose on LinkedIn.
CLAD, Pulmonary GVHD Have Similar Clinical Traits, Research Needs
Fine-tuning clinical phenotypes and identifying effective treatments remain challenging in chronic lung allograft dysfunction (CLAD) after lung transplantation and chronic graft-versus-host disease (GVHD) after allogeneic hematopoietic stem-cell transplantation.
Real-World Analysis Explores Clinical Activity, Safety of PD-1 Inhibition in Advanced BCC
Locally advanced or metastatic basal cell carcinoma can be challenging to treat, but programmed death receptor 1 inhibition may hold potential as a tolerable, effective approach in patients of all ages.
Review Highlights Progress and Challenges in Treating HIV/AIDS-Associated Lymphoma
Significant progress has led to improved survival in patients with HIV/AIDS, but lymphoma remains a leading cause of morbidity and mortality in this patient population.
RAS Inhibitors May Hold Potential as Preventive for Acute Chest Syndrome in Sickle Cell Disease
A retrospective study assessed hospital readmission rates in patients with sickle cell disease and acute chest syndrome who took angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers vs those who did not.
Adolescent, Young Adult Males With Sickle Cell Disease Lack Knowledge of Fertility Implications, Study Shows
Improved management of sickle cell disease has vastly improved life expectancy and reduced morbidity for affected patients, but the disease itself and its treatments carry fertility risks that many young patients and their caregivers are unaware of.
Case Series Suggests Venetoclax Plus Hypomethylating Agent Therapy Tolerable, Effective in Very Elderly AML Patients
Very elderly patients with acute myeloid leukemia have historically been limited to less intensive, less effective treatment regimens. A recent series of cases suggests age alone should not be a limiting factor for effective treatment.
Clostridioides difficile Infection May Be Underdiagnosed in Health Care Facilities, Study Finds
A study of hospitals and long-term care facilities in Louisville, Kentucky, found low rates of Clostridioides difficile testing in patients with new-onset diarrhea who are frequently infected.
Review Addresses Antifungal Prophylaxis in AML and Provides Guidance for Novel Agents
Patients with acute myeloid leukemia (AML) who have undergone intensive chemotherapy are at a very high risk for invasive fungal disease, and a changing treatment landscape warrants further research on drug-drug interactions and outcomes.
Review Highlights Treatment Landscape, Insights on Pregnancy Management for ET or PV
Polycythemia vera and essential thrombocythemia are both slow-progressing conditions and treated mainly with symptom management, but novel agents and gene targets have changed the landscape in recent years.
SHEA Updates Guidelines for Central Line-Associated Bloodstream Infection Prevention in Hospitals
Preventing health-care–associated infections in acute-care hospitals is crucial for patient well-being and health care cost burden, and comprehensive guidelines based on current research are an important aspect of prevention.
Novel Therapies Targeting Vasoconstriction and Vascular Remodeling May Improve Outcomes in PAH
Drugs currently marketed for pulmonary arterial hypertension have been able to extend the lives of patients but have shown limitations in their ability to prevent or reverse the disease. A novel combination approach may hold promise in future treatments.
Provider Awareness, Systematic Referral Processes May Help Peer Support Uptake in CKD
Peer support can be a helpful facet of chronic kidney disease (CKD) self-management, but inconsistent provider awareness and referral practices are barriers to uptake at Canadian clinics.
Simple Surveys May Help Phenotype and Target Treatment for Chronic Cough
A study of the Austrian general population found that most chronic cough cases could be assigned a phenotype through a simple survey-based assessment that could help target treatment to individual cases.
RNA Sequencing Identifies Novel, Specific Biomarkers in Pterygia
While risk factors for pterygia are well-known, the underlying disease mechanisms have not been fully clarified in past studies. A new analysis using RNA sequencing pinpointed ptergyia-specific biomarkers and potential therapeutic targets.
Patients With CKD Have Higher Risk of HFrEF After PCI
A recent study found chronic kidney disease (CKD) to be an independent risk factor for incident heart failure with reduced ejection fraction (HFrEF) following percutaneous coronary intervention (PCI).
Case Study Presents 3 Potential Novel Targets in Acute Myeloid Leukemia
Acute myeloid leukemia is a complicated heterogenous hematological cancer with a poor prognosis, but novel targets may lead to improved treatment and outcomes going forward.
Real-world Study Shows Ruxolitinib May Reduce Arterial Thrombosis in Polycythemia Vera
Previous studies have shown ruxolitinib effective in symptom relief and hematocrit control for hydroxyurea-resistant polycythemia vera, but its role in disease progression is not yet clear.
Review Highlights Progress and Potential in Immunotherapy Plus Radiotherapy for Cancer Treatment
With further research, a selection of combination therapies could increase patient response in various cancer types.
AKR1C3 Expression May Hold Potential as a Biomarker, Clinical Target in T-ALL
Aldo-keto reductase 1C3 (AKR1C3) has been identified as a potential biomarker and target in several cancers, and a recent study found it to be a potential biomarker in T acute lymphoblastic leukemia/lymphoma (T-ALL).
Novel Internet-Based Hospital-to-Home Model for Nutritional Nursing Effective in Patients With CKD
Continual nutrition modification is crucial in patients with moderate to advanced chronic kidney disease (CKD), and more interactive at-home solutions hold potential to improve nutritional nursing models after hospital discharge.
Study Finds Autologous Stem Cell Transplantation Safe, Effective in Patients With Multiple Myeloma, Chronic Kidney Disease
Chronic kidney disease is a common complication in multiple myeloma, and a recent study found it is safe to treat this patient population with autologous stem cell transplantation.
Study Finds Self-reported Historical Influenza Vaccination Status Reliable in Most Health Care Personnel
Self-reported vaccination statuses are often used in studies of influenza vaccination, and a recent study found this method reliable in health care personnel who receive the vaccine consistently.
Mesenchymal Stem Cells Induce Cell Proliferation, Inhibit Dexamethasone Effectiveness in MM
Mesenchymal stem cells are known to promote tumor growth and metastasis in multiple myeloma (MM), but a recent study found they may also inhibit the effects of the corticosteroid dexamethasone, a common medication for the hematologic malignancy.
Review Explores Glycemic Monitoring Methods in Chronic Kidney Disease
Monitoring glycemia in chronic kidney disease comes with challenges, but emerging strategies warrant more research in this patient population.
Neurocognitive Changes After CAR T-Cell Therapy for NHL Similar to Other Cancers
With an increasing number of longer-term survivors treated with chimeric antigen receptor (CAR) T-cell therapy for non-Hodgkin lymphoma (NHL), more research is needed to confirm its effects on neurocognitive performance.
Alternative K-mer–Based Approaches Offer Faster Clostridioides difficile Genome Analysis, but Leave Room for Improvement
As more bacterial DNA sequences are identified, the computational challenges associated with whole-genome sequencing have researchers looking to other potential methods of tracking and understanding differences in bacterial pathogens such as Clostridioides difficile.
Sodium Intake Alone May Not Affect Risk of Chronic Kidney Disease, Study Finds
A recent study on Hispanics/Latinos in the United States found that lower potassium intake and higher sodium-to-potassium ratios may be more predictive of chronic kidney disease risk.
Higher Risk of CV Mortality Seen in Patients With MM Compared With General Population
While studies have explored risks among patients with multiple myeloma, recent research is the first to compare cardiovascular mortality risk in multiple myeloma to that of the general population.
LMOD3 Gene Variant Identified in Hypersomnolence Case With Potential Kleine-Levin Syndrome
Kleine-Levin syndrome is rare and difficult to diagnose, especially when symptoms are atypical. Recent research points to LMOD3 variations as a potential diagnostic marker if confirmed by further research.
Study Characterizes Peripheral Nerve Invasion in HCCA With Novel WHLS Method
Analyzing whole-mount histologic large sections is not a new practice, but a new strategy was needed to fully characterize peripheral nerve invasion in hilar cholangiocarcinoma.
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