Rose is a freelance writer for The American Journal of Managed Care® (AJMC®), where she previously worked as an editor.
She has a BA in journalism & media studies and Spanish from Rutgers University. You can connect with Rose on LinkedIn.
T1D Risk-Taking Survey Reliable, Valid for Use Among Adolescents
The Diabetes-Specific Risk-Taking Inventory proved useful in assessing risk-taking behavior in adolescents with type 1 diabetes (T1D), but future research on potential interventions is needed.
Role of Immunotherapy Across BRAF-Mutant NSCLC Requires Clarification
In patients with BRAF-mutated non–small-cell lung cancer (NSCLC), further research is needed to identify more treatment options that address the scope of subsets in this population.
Population-Based Study Finds Racial Disparities in MDS Outcomes
Research presented at the 2022 American Society of Clinical Oncology Annual Meeting shows White patients with myelodysplastic syndrome (MDS) have worse overall survival outcomes than African American patients, contrary to previous findings in other cancer types.
Risk Factors for Hemophilia-Related Bleeding From Prophylaxis Explored in New Study
Creating and validating effective risk assessment models could help facilitate appropriate prophylaxis for hemophilia, but more research is needed to confirm the prognostic value of various clinical risk factors and biomarkers.
Palliative Care Shortcomings for Patients With Hematologic Malignancies Addressed in New Review
A recent review explored current palliative care practices for patients with hematologic cancers compared with solid tumor cancers.
Interim Phase 2 Trial Results Show Quadruplet Regimen Tolerable, Effective in MM
Early results of a multicenter phase 2 trial exploring the efficacy of daratumumab, pomalidomide, dexamethasone, and ixazomib treatment suggest the regimen is safe and effective in relapsed or refractory multiple myeloma (MM).
Adjuvant Pembrolizumab Shows Favorable Health-Related Quality-of-Life Results in Resected Melanoma
An interim analysis of the KEYNOTE-716 trial of adjuvant pembrolizumab supports its use in the adjuvant setting for patients with resected melanoma.
Study Shows Significant Disparities in Worldwide Rates of Non-Hodgkin Lymphoma
Recent research used incidence and mortality data from the GLOBOCAN 2020 database to gain insight into worldwide patterns of non-Hodgkin lymphoma in 2020.
Review Highlights Nanomedicine as Potential Drug Delivery Strategy in Multiple Myeloma
A recent review summarized the current knowledge and treatment paradigm of multiple myeloma, including recent advances and challenges in nanomedicine.
Transfusion-Dependent Patients With MDS Vary in Treatment Experiences, Preferences
Transfusion dependence is common for patients with myelodysplastic syndromes (MDS), but real-world data show inconsistent patient experiences and varied transfusion practices between countries.
Major Adverse Cardiac Events Related to ICI Treatment Explored in New Study
Major adverse cardiac events are rare but serious in patients treated with immune checkpoint inhibitors (ICIs), and increased awareness is crucial to identify and treat these conditions in a timely manner.
Exploring the Landscape of Current Immune Checkpoint Inhibitors
Immune checkpoint inhibitors have changed the way certain cancers are treated, but more can be done to optimize treatment and improve patient responses.
Parental Age May Be Linked With Childhood Cancer Risk, but More Research Is Needed
A recent meta-analysis aimed to clarify the relationship between parental age and solid tumor pediatric cancers, but more studies are necessary to overcome the limitations of available research.
Review Highlights Potential for CLDN18.2 as a Therapeutic Target in Various Cancers
While no agents are approved just yet, a variety of promising drugs targeting CLDN18.2 are undergoing early research and clinical trials for several cancer types.
Study Examines T1D Eating Patterns of Youth After COVID-19 Lockdowns in Italy
Findings of a study on children and adolescents with type 1 diabetes (T1D) in Italy suggest lockdown periods during COVID-19 did not increase disordered eating symptoms or adversely affect disease management.
CD300 Molecules May Be Influential Immune Regulators, Therapy Targets in AML
Finding therapeutic targets for acute myeloid leukemia (AML) has proven challenging, but a set of immune-regulating molecules may hold promise as biomarkers and targets.
Novel Prognostic Biomarkers Indicate Prognosis in Acute Myeloid Leukemia
A novel prognostic model based on N 6-methyladenosine-associated long non-coding RNAs demonstrated accuracy in determining high- and low-risk disease, suggesting the associated risk value may have potential as a novel biomarker.
Study: Suggested Cyclosporine Levels Posttransplant May Be Too Low to Prevent GVHD
Preventing graft-versus-host disease (GVHD) after allogeneic stem cell transplant is a key aspect of patient management, but current cyclosporine concentration guidelines may not be sufficient, according to a recent study.
Adjuvant Therapy Shows No Significant Benefits After Cholangiocarcinoma Resection
A retrospective study found low treatment adherence and no significant benefits to adjuvant chemotherapy or chemoradiotherapy following cholangiocarcinoma resection.
Individualized Antimicrobial Treatment, Prophylactic Regimens May Help With GVHD After Liver Transplant
A recent study aimed to provide insight and guidance for managing graft-versus-host disease in patients after liver transplantation.
Study Identifies Novel PD-L2 Variant as Possible Predisposition Indicator in Lymphoma
Whole-exome sequencing of a family with early-onset cancers found a novel variant in programmed cell death 1 ligand 2 that could potentially indicate germline predisposition to lymphoma.
Review of Current EoE Treatment Landscape Highlights Several Promising Agents
A recent review points to a host of potentially disease-modifying agents currently in clinical trials.
Study Finds Adjuvant Therapy Beneficial for Distal Cholangiocarcinoma With Lymph Node Metastasis
Recurrence is common in patients with distal cholangiocarcinoma, even after curative surgical resection. In a recent study, postoperative adjuvant therapy correlated with improved survival, but only in certain patients.
AML and COVID-19: Chemotherapy Delay May Be the Best Approach
Patients being treated for acute myeloid leukemia (AML) who are diagnosed with COVID-19 may be best served by chemotherapy delay until after COVID-19 has run its course.
Study Combines Neurological Assessments to Better Identify SMA in Newborns
A small study aimed to increase the likelihood of detecting minor neurological symptoms of spinal muscular atrophy via a combination of tests specifically suited to newborns.
Study Suggests Ocular GVHD Is Underdiagnosed in Patients After Hematopoietic Stem Cell Transplantation
A survey of blood and bone marrow transplant patients found that many who fit current criteria for ocular graft-versus-host disease have not been diagnosed.
TIGIT May Hold Potential as a Marker of CAR T-Cell Exhaustion and Therapeutic Target in Non-Hodgkin Lymphoma
A recent study identified TIGIT as a marker of chimeric antigen receptor (CAR) T-cell exhaustion and found it to improve CAR T-cell therapy efficacy in preclinical models.
Radiomics-Based Models Can Accurately Diagnose MM and Bone Metastases, Study Finds
Differentiation between multiple myeloma (MM) and bone metastases from other cancers can be difficult, but radiomics-based models have potential to improve diagnostic accuracy.
Review Highlights Tumor Microenvironment Features Contributing to Immunotherapy Resistance
Treatment resistance is a significant challenge in immunotherapy, but it is not fully understood. A recent review summarized 5 tumor microenvironment traits that may inhibit therapy effectiveness and potential strategies to improve therapy responses.
Adolescent, Young Adult Leukemia Survivors Face Higher Long-term Mortality Rates
While 5-year survival in adolescent and young adult leukemia has improved in recent decades, this patient population still faces increased long-term mortality compared with the general public.
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