Skin Cancer

The AJMC® Skin Cancer compendium is a comprehensive resource for clinical news and expert insights about melanoma and other skin cancers.

Latest News
April 28th 2025

Immediate Nasal Reconstruction Following BCC Removal Is Viable

April 21st 2025

Rare Autoimmune Disorder Linked With Increased Risk of Certain Skin Cancers

April 17th 2025

Early Adjuvant Immunotherapy Discontinuation Does Not Affect Melanoma Recurrence Risk

April 10th 2025

Novel Methods Could Reshape Skin Cancer Diagnostics

April 2nd 2025

Deep Learning Tool Differentiates Keloids From Malignant Lesions Without Dermoscopy

Dr. Jason Luke leads a panel discussing immunotherapy advances in Cutaneous and Basal Cell Carcinoma

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December 5th 2022

Dr Neil Gross: Cemiplimab Has Great Potential in cSCC

November 12th 2022

Dr Neil Gross on Potential Impact of Future Novel Treatments for cSCC

November 2nd 2022

Dr Neil Gross Discusses the Implications of pCR on Additional Treatment in Skin Cancer

October 20th 2022

Dr Neil Gross: QOL Improvement Likely Following Treatment With Cemiplimab for cSCC

October 3rd 2022

Dr Neil Gross: Cemiplimab Is Producing Encouraging Results in Resectable cSCC

October 4th 2021

Dr Christine Ko on Making Tough Skin Cancer–Related Decisions for Transplant Patients

September 28th 2021

Dr Todd Schlesinger: Tissue-Sparing Mohs Surgery Is Highly Accurate

September 10th 2021

Dr Christine Ko: Transplant Patients Face Unique Skin Cancer Risks

September 5th 2021

Dr Todd Schlesinger on How Medical, Cosmetic, Research Dermatology Interact

August 19th 2021

Dr Todd Schlesinger: Morphology, Immunosuppression Affect Actinic Keratosis Outcomes

More News

Estrogen | Image credit: Debalina - stock.adobe.com
March 20th 2025

Estrogen Therapy May Increase Risk of 3 Skin Cancers

Hayden E. Klein
Researchers of a Swedish study advise physicians to consult with their patients about these risks and take extra precautions, but did not recommend discontinuation of any of the drugs studied.
Doctor screening patient for skin cancer | Image credit: Seventyfour – stock.adobe.com
March 14th 2025

Patients Prefer AI in Skin Cancer Screening as an Assistive Tool, Not a Replacement

Hayden E. Klein
Patients expressed concern that overreliance on artificial intelligence (AI) could lead to clinicians losing their skills, both medical and interpersonal.
Report Highlights Role of Cancer-Associated Fibroblasts in Melanoma Metastases
March 13th 2025

Report Highlights Role of Cancer-Associated Fibroblasts in Melanoma Metastases

Jared Kaltwasser
The study could open the door to potential novel therapeutic targets.
Newer technology may play an important role in aiding early skin cancer diagnosis, new research suggests. | Image credit: InsideCreativeHouse - stock.adobe.com
March 11th 2025

AI, Other Technologies May Help Narrow Gender Disparities in Melanoma

Jared Kaltwasser
Men with melanoma tend to be diagnosed later and have worse outcomes. Artificial intelligence can help change that, a review suggests.
Doctor conducting a skin cancer check | Image credit: InsideCreativeHouse - stock.adobe.com
March 6th 2025

Image-Guided Superficial Radiation Therapy Safe, Effective Treatment for Nonmelanoma Skin Cancer: Expert Panel

Emma Andrus
A dermatology expert panel confirms image-guided superficial radiation therapy as a safe, effective first-line treatment for select nonmelanoma skin cancer cases.
Older man after skin cancer surgery with bandage on face | Image credit: steheap – stock.adobe.com
February 7th 2025

Keratinocyte Skin Cancer Surgery Considered Safe, Effective in Older Patients

Hayden E. Klein
A single-center study suggests the surgery is safe and effective even when tumors are large or located in high-risk areas.
Dermatologist examining skin | Image credit: Medical Works – stock.adobe.com
January 20th 2025

Combination Immunotherapy Offers New Pathway for Skin Cancer Prevention

Alexandra Gerlach
A topical treatment combining calcipotriol and 5-FU shows promise in reducing premalignant lesions and lowering skin cancer risk by activating Th2 immunity.
Doctor inspecting skin cancer | Image credit: InsideCreativeHouse – stock.adobe.com
January 17th 2025

Adjuvant Cemiplimab Significantly Improves Disease-Free Survival in High-Risk Skin Cancer

Hayden E. Klein
Cemiplimab significantly reduced the risk of recurrence or death in patients with high-risk cutaneous squamous cell carcinoma (CSCC) post-surgery.
AI-generated image of a pill saying metformin | Image credit: Giama22 – stock.adobe.com
January 15th 2025

Diabetes Drug Metformin May Have Another Use: Protecting Against Skin Cancer

Hayden E. Klein
However, metformin did not protect Black patients against squamous cell carcinoma specifically.
Skin cancer | Image credit: anna.stasiia – stock.adobe.com
January 11th 2025

Skin Cancer Disparities Persist in Latine/Hispanic Population

Hayden E. Klein
Latine individuals in the US face higher morbidity and mortality in skin cancer outcomes despite lower lifetime risk.
Advancing health equity can be achieved through community engagement | image credit: Andrii - stock.adobe.com
October 16th 2024

Community Engagement, Culturally Tailored Care as a Gateway to Advancing Health Equity

Kyle Munz
Many talks at the Association of Cancer Care Centers (ACCC) 41st National Oncology Conference advocated for the adoption of culturally relevant care, the leveraging of community partnerships, and community engagement to build better trust with patients and improve outcomes.
Biofrontera's red-light LED has been approved for the treatment of actinic keratosis | image credit: marog-pixcells - stock.adobe.com
June 28th 2024

FDA-Approved Red-Light LED Lamp Released for Patients With Actinic Keratosis

Tim Smith
The announcement followed the release of the RhodoLED XL red light-emitting lamp, to be used in combination with aminolevulinic acid hydrochloride topical gel, 10% for actinic keratoses.
skin cancer | Image Credit: uffoow-stock.adobe.com
June 28th 2024

Certain Melanoma Subtype May Be More Sensitive to NK, T Cells

AJMC Contributor
Of 7 subtypes identified 10,000 melanoma cells, C4 Melanoma COCO1A was the only to show indications of being more sensitive to natural killer (NK) and T cells.
Medicaid coverage | image credit: nelzajamal - stock.adobe.com
June 20th 2024

Further Medicaid Expansion Would Benefit Patients With Melanoma, Study Finds

Kyle Munz
A poster presented at the 2024 American Society of Clinical Oncology annual meeting argued the benefits that Medicaid expansion can bring to patients with melanoma.
Pregnancy-associated melanoma is a rare occurence that impacts 1 in 2200 pregnancies | image credit: Alik Mulikov - stock.adobe.com
June 15th 2024

Management of Melanoma During Pregnancy Explored at ASCO 2024

Kyle Munz
Two posters presented at the 2024 American Society of Clinical Oncology annual meeting revealed real-world data on the outcomes and management strategies associated with melanoma during pregnancy.
Skin cancer risk may be associated with immunosuppressant medication, although multiple studies exploring this relationship have not drawn concrete conclusions | image credit: Damian Gretka - stock.adobe.com
June 13th 2024

Link Between Skin Cancer and Immunosuppressants Needs Further Research

Kyle Munz
At the 2024 American Society of Clinical Oncology annual meeting, an abstract presenting real-world data stressed the need for further research regarding the association between immunosuppressant medication and the development of skin cancer.
Skin cancer checkup concept with cancer ribbon | image credit: Monstar Studio - stock.adobe.com
June 10th 2024

Metformin for Melanoma Holds Potential Benefits for Patients

Kyle Munz
Metformin showed promise for improving the overall survival rate of patients with melanoma; however, this result may be an indirect consequence of the drug.
Skin cancer screening | Image credit: Viktoriia - stock.adobe.com
May 31st 2024

Keratinocyte Cancers Most Commonly Located on the Head and Neck, US Study Finds

Rose McNulty
A large Medicare cohort study found that the most common locations of procedurally treated keratinocyte cancers in the US were the head and/or neck for both squamous cell carcinomas and basal cell carcinomas.
Person Operating Smartphone | image credit: Production Perig - stock.adobe.com
May 31st 2024

Concerns About AI-Based Dermatologic Mobile Apps

Kyle Munz
An analysis that overviewed dermatologic mobile apps with artificial intelligence (AI) features led researchers to voice concerns about the use of this technology in its current state.
Clinician Marking Non-melanoma Skin Cancer Lesion for Removal | image credit: Pixel-Shot - stock.adobe.com
May 13th 2024

Patients With Nonmelanoma Skin Cancer Prefer RSCT Over Surgery

Kyle Munz
A follow-up study utilizing interviews and survey responses demonstrates that patients prefer rhenium-188 skin cancer therapy (RSCT) over surgery in the treatment of their non-melanoma skin cancer.
Adverse Drug Reaction Warning | image credit: Balint Radu - stock.adobe.com
May 9th 2024

Patients With Advanced, Recurrent Melanoma May Experience Lasting AEs From ICM Therapy

Kyle Munz
A cross-sectional, mixed-methods study found that adverse effects (AEs) can occur even after 1 year of treatment with immune checkpoint modulator (ICM) therapy in patients with melanoma.
Basal Cell Carcinoma | image credit: Laura Ballard - stock.adobe.com
May 3rd 2024

Exploration Into Super-Giant Basal Cell Carcinoma Calls for Future Research

Kyle Munz
A systematic analysis demonstrated the rarity of super-giant basal cell carcinomas and the need for further characterization of these understudied skin cancers.
Skin cancer check | Image credit: InsideCreativeHouse - stock.adobe.com
April 30th 2024

Survivors of Early-Stage Melanoma Have High Rates of Fear of Recurrence, Study Finds

Rose McNulty
The study aimed to improve the understanding of lived experiences and the fear of recurrence among survivors of localized, stage 0 to IIA cutaneous melanoma.
Skin Check for Melanoma | image credit: cunaplus - stock.adobe.com
April 26th 2024

Exploration of Melanoma Incidence, Mortality Rates Urges Further Research

Kyle Munz
A retrospective analysis out of Denmark could not find a causal relationship to explain trends in melanoma incidence and mortality rates, demonstrating the need for more research in this area.
AI-Generated CT Equipment Concept | image credit: StraSyP - stock.adobe.com
April 15th 2024

Dr Michael Farwell on FDG PET/CT Imaging to Predict Immunotherapy Response in Advanced Melanoma

Kyle Munz
Michael Farwell, MD, associate professor of radiology at the Hospital of the University of Pennsylvania, provides insights into a study on the benefits of using 18F-fluorodeoxyglucose (FDG) PET/CT imaging to detect metabolic tumor changes in skin cancer.
AI-Based Smartphone App Proves Reliable in Diagnosis of Melanoma
April 9th 2024

AI-Based Smartphone App Proves Reliable in Diagnosis of Melanoma

Kyle Munz
A prospective study evaluating the efficacy of an artificial intelligence (AI)–based clinical support system further demonstrated the reliability of AI or machine learning as a diagnostic tool in skin cancer.
Cancerous Cells Concept | image credit: Dr_Microbe - stock.adobe.com
April 5th 2024

Yes-Associated Protein May Hold Prognostic Value in Cutaneous Melanoma

Kyle Munz
A retrospective study analyzing tissue assays from patients with cutaneous melanoma demonstrated the promise of yes-associated protein (YAP) as a predictive biomarker for melanoma prognosis.
Collaboration With AI Concept | image credit: ipopba - stock.adobe.com
March 30th 2024

AI Accurately Predicts Skin Cancer Risk Based on 2D Facial Images

Kyle Munz
An artificial intelligence (AI) mode was more accurate in assessing patient risks for skin cancer through the analysis of 2D facial images compared with more traditional risk-factor screening.
Man Prior to Skin Examination | image credit: New Africa - stock.adobe.com
March 28th 2024

Risk for Second Primary Melanoma Increases After Primary Melanoma Diagnosis as Men Age

Kyle Munz
A population-based cohort study out of Norway has found that older men have a higher risk of developing second primary invasive melanoma following an initial primary melanoma, suggesting the benefits of increased surveillance in these patients.
Radiation Therapy Model | image credit: Andrii - stock.adobe.com
March 26th 2024

Radiation Therapy Associated With Elevated Skin Cancer Risk in Patients With Breast Cancer

Kyle Munz
Results from a retrospective cohort study analyzing patients with breast cancer bolster reports of an association between radiation therapy and subsequent risks of skin cancers.
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