Skin Cancer

The AJMC® Skin Cancer compendium is a comprehensive resource for clinical news and expert insights about melanoma and other skin cancers.

Real-World Analysis Explores Clinical Activity, Safety of PD-1 Inhibition in Advanced BCC

May 18th 2022, 5:20pm


Locally advanced or metastatic basal cell carcinoma can be challenging to treat, but programmed death receptor 1 inhibition may hold potential as a tolerable, effective approach in patients of all ages.

Apatinib Prompts Responses in Patients With Recurrent Melanoma

May 15th 2022, 11:17am


The drug yielded partial responses in 2 of 15 patients in this single-arm, phase 2 study.

Melanoma Prevalence, Mortality Mostly Stable Over the Past 30 Years

May 13th 2022, 12:08pm


Data from this new study suggest melanoma cases rose at a slower rate in lower-income countries, but the authors say that may be due to differences in case documentation.

Study Suggests Awareness Alone Will Not Solve Skin Cancer Overdiagnosis Issue

May 9th 2022, 10:01pm


More experienced dermatopathologists were less likely to see overdiagnosis as a significant public health problem, a new survey showed.

Investigation Yields Potential New Genetic Biomarker for Anti–PD-1 Success in Melanoma

May 5th 2022, 3:24pm


Investigators found 6 genes associated with cancer-associated fibroblasts that appear to correlate with response to anti-PD-1 immunotherapy.

Genetic Advances Could Change Management of Uveal Melanoma

May 2nd 2022, 11:03pm


Although classic methods of risk stratification still hold value, the authors said genetic analysis holds significant promise.

Australian Study Finds General Practitioners Tend to Adhere to Guidelines When Treating Melanoma

April 27th 2022, 6:15pm


The finding is important because evidence suggests it is becoming more common for patients to receive care from a general practitioner for skin cancer, versus a surgeon or dermatologist.

Dr Martin Dietrich Describes Need to Move Quickly With “Aggressive, Unpredictable” Melanoma

April 27th 2022, 4:01pm


Martin Dietrich, MD, PhD, of Florida Cancer Specialists spoke with The American Journal of Managed Care® (AJMC®) on risk factors in melanoma, as well as the need for genomic testing and rapid action for a cancer that can progress very quickly.

Soluble Microenvironment Appears to Impact How Melanoma Cells Interact With Immune Cells

April 24th 2022, 3:22pm


Inflammatory microenvironments appear to enhance melanoma cells’ ability to control T-cell responses.

DNA Mismatch Repair Proteins May Predict ICI Response in Cutaneous Melanoma

April 22nd 2022, 1:13pm


Patients with reduced DNA mismatch repair protein expression were more likely to respond to immune checkpoint inhibitors (ICIs), although this study had a small sample size.