Jared is a freelance writer for The American Journal of Managed Care® (AJMC®), and previously worked as a senior editor for HCPLive® at MJH Life Sciences®.
He has an MA from University of Sioux Falls. You can connect with Jared on LinkedIn.
CTEPH Treatment, Management Varies Widely Across Globe
A new report shows wide variability in terms of which patients with chronic thromboembolic pulmonary hypertension (CTEPH) are deemed eligible for pulmonary endarterectomy and balloon pulmonary angioplasty.
Study Identifies Risk Factors for Progression From Low-Risk MDS
The findings show most patients with low-risk myelodysplastic syndrome (MDS) will die before progression.
Chinese Patients With gMG Respond Well to Efgartigimod
A new report offers safety and efficacy data on a population with generalized myasthenia gravis (gMG) not represented in the drug’s pivotal phase 3 trial.
Lexeo Shares Positive Interim Data for FA Cardiomyopathy Gene Therapy
The therapy led to increased frataxin levels and decreased left ventricular mass in patients with Friedreich ataxia (FA) cardiomyopathy, the authors said.
Sponsor Terminates MATTERHORN Trial of Roxadustat for Low-Risk MDS
Patients with myelodysplastic syndrome (MDS) in the treatment arm were more likely to achieve transfusion independence, but the difference vs placebo was not statistically significant.
Report Recommends Strategy to Identify CLL in Patient With Posterior Uveitis
It is rare for patients with chronic lymphocytic leukemia (CLL) to present with ocular involvement, but a mutational test could help clinicians identify patients more quickly.
VenR Achieves Strong Results in Japanese CLL/SLL Cohort
Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) are rare in Japan, but a new report affirms the effectiveness of venetoclax (Venclexta) and rituximab (Rituxan) (VenR) in this population.
In Acute Leukemia, Chance of Response Is Patient’s Top Concern
Quality of life was also a top concern among patients when asked about their priorities if they experienced relapse or were refractory to therapy.
Stem Cell–Based Gene Editing Strategy Shows Promise in DMD
Early tests show stem cells can be used to spark expression of a miniature version of the dystrophin protein.
Infection Risk With BTK Inhibitors Low, New CLL Study Finds
Only about 1% of patients with chronic lymphocytic leukemia (CLL) developed an invasive fungal infection while on a Bruton’s tyrosine kinase (BTK) inhibitor, investigators found.
Field Study Highlights Differences in Factor IX Variant Lab Results
Different types of assays led to different results in measures of factor IX variant FIX-R338L, the authors found.
In Patients With Hemophilia A, Physical Activity Levels Low
A new study also found a lack of correlation between physical activity levels and bleeding episodes among people with hemophilia A.
HMA Therapy Translates to More Time at Home for Patients With AML
People receiving hypomethylating agent (HMA) therapy spent 33 more days at home than people receiving anthracycline-based therapy in the first year after diagnosis.
More People With T1D Are Living Into Old Age
A new prevalence study shows more people are living beyond age 65 with type 1 diabetes (T1D).
Community Practitioner–Led Hypertension Program Yields Strong Results
A Chinese study shows hypertension management led by nonphysicians can be safe and effective.
Emicizumab Has Strong Safety, Efficacy Record in Real-World Usage
The most common treatment-related adverse events were injection site reactions, the study found.
Case Highlights Difficulties Identifying MG Secondary to ICI Therapy
There currently are no guidelines on how to treat this patient group, despite a high risk of mortality.
Gender May Affect Whether, Why Patients With T1D Exercise
Men are less likely than women to desire community when exercising, the authors found.
Real-World Database Yields New Potential Safety Signals for Bendamustine
The authors said their analysis should help clinicians better monitor patients for potential adverse events.
Consortium: PROs Have Key Role in MDS Trials
The coalition said, however, that patient-reported outcomes (PROs) in the myelodysplastic syndrome (MDS) space will be most meaningful if they are collected rigorously and if the data are transparent.
Long-Term Analysis From DUO Trial Affirms Benefits of Duvelisib
The new data shed light on long-term outcomes for patients receiving duvelisib, although the investigators said the treatment landscape has also shifted significantly since the original trial.
Case Report Finds SSRIs Work Alongside MG Therapy in Teen Patient
The report found a selective serotonin reuptake inhibitor (SSRI) did not offset the effects of myasthenia gravis (MG) medication.
Study Identifies New Links Between Monocytes, T1D Progression
A new report builds on previous research that could help scientists better understand type 1 diabetes (T1D) risk.
Hemophilia Not Linked With Cognitive and Behavioral Outcomes in Children
However, investigators said there is some evidence suggesting attention-deficit/hyperactivity disorder may be more common in certain age groups of children with hemophilia.
Case Report: Abducens Nerve Palsy Could Be Sign of Myasthenia Gravis
A 68-year-old man was diagnosed with ocular myasthenia gravis after presenting with double-vision and photophobia.
SID Heightens Infection Risk in Patients With B-Cell Malignancies
A new report finds secondary immunodeficiency disease (SID) also increases the risk of mortality in patients with B-cell malignancies.
Gene Therapy Offers Promise in Treating Inborn Errors of Immunity
A new report says early evidence of using gene therapy to treat monogenic diseases offers reason for optimism.
Closed-Loop Glucose Management Improves Outcomes in Youth With T1D
Patients with type 1 diabetes (T1D) reported improved glucose outcomes, but they also said their sleep and quality of life benefited.
Exercise-Induced Hypertension a Risk Factor for Sudden Cardiac Death, Review Finds
The findings show exercise-induced hypertension increases myocardial oxygen demand.
Study: Care Costs for R/R DLBCL Increase With Each Line of Therapy
New therapies are helping patients, but are also driving up overall costs of care.