The AJMC® Chronic Kidney Disease compendium is a comprehensive resource for clinical news and expert insights on the condition and treatment of loss of kidney function.
December 27th 2022
The top 5 most-read articles about chronic kidney disease (CKD) focused on finerenone benefits, anticoagulants, dementia association, and more.
December 23rd 2022
Kidney Week 2022 focused on effectiveness of treatment for chronic kidney disease, health misinformation, and outcomes in chronic kidney disease, among other topics.
December 22nd 2022
Lower estimated tubular secretion was found to be associated with a faster decline of estimated glomerular filtration rate (eGFR) but wasn’t associated with progression of chronic kidney disease or cardiovascular disease.
December 19th 2022
A retrospective study found roxadustat to be more effective in improving hemoglobin levels in patients who had with chronic kidney disease (CKD) compared with recombinant human erythropoietin.
December 15th 2022
Implantable cardioverter defibrillators (ICDs) were found to have a beneficial effect on mortality in patients with chronic kidney disease (CKD).
DOAC Prescriptions Gradually Displaced Warfarin in AF, CKD Treatment
Prescriptions for treatment of atrial fibrillation (AF) and chronic kidney disease (CKD) have primarily been prescriptions for direct oral anticoagulants (DOACs), displacing warfarin as the primary treatment.
CKD Associated With Abdominal Aortic Aneurysm
A cohort study found that chronic kidney disease (CKD) was associated with the development of abdominal aortic aneurysm, with risk increasing as CKD stage advanced.
Patients With CKD Report Burden Could Improve Through Communication With Physicians
Speaking with patients diagnosed with chronic kidney disease (CKD) about the burdens associated with care could help improve understanding of the disease and their communication with health care professionals.
Kidney Failure–Free Survival Increased With ACE, SGLT2 Inhibitors
Treatment with an angiotensin-converting enzyme (ACE) inhibitor/angiotensin receptor blocker and sodium-glucose cotransporter-2 (SGLT2) inhibitor combination demonstrated better outcomes in kidney failure.
Nonalcoholic Fatty Liver Disease Related to Increased Incidence of CKD
A new review has found that increased incidence of chronic kidney disease (CKD) may be seen among patients with nonalcoholic fatty liver disease.
Examining the Impact of CKD on Individuals, Caregivers
The studies reviewed estimates of economic and humanistic impact on both patients with chronic kidney disease (CKD) as well as their caregivers.
New Clinical Guidelines Recommend Finerenone for CKD Associated With T2D
Updated Kidney Disease: Improving Global Outcomes guidelines and a consensus report with the American Diabetes Association support the use of finerenone in certain patients who have chronic kidney disease (CKD) that may be linked to type 2 diabetes (T2D).
What We’re Reading: Tenapanor Recommended for Dialysis; Home Births Up During Pandemic; Call for RSV, Flu Emergency
FDA advisers voted in favor of approving Ardelyx’s tenapanor for patients with chronic kidney disease on dialysis; US home births increased by about 12% between 2020 and 2021; surges in respiratory viruses, especially respiratory syncytial virus (RSV) among younger children are putting pediatric hospitals at capacity.
Glomerular Filtration Rate Based on Cystatin C More Accurate for Predicting CVD, Mortality
A prospective population-based cohort study found that glomerular filtration rate based on cystatin C was more sensitive and specific for cardiovascular disease (CVD) and mortality risks compared with glomerular filtration rate based on creatinine.
Removal of Race Adjustment Improved Bias, Accuracy in eGFR Equations for Black Adults
A systematic review found that alternative approaches to calculating estimated glomerular filtration rate (eGFR) were worth looking into to properly account for diversity in populations.
Contributor: Congress Must Fix Patient Protection Statute Upended by Supreme Court
The author, the dean of the College of Ethnic Studies at California State University Los Angeles, says a Supreme Court ruling could upend insurance protections for patients with kidney diseases, disproportionately hurting those who are Black, Hispanic, Asian, and other diverse ethnicities.
NKF Touts Potential of Kidney Disease Patient Registry to Yield Real-World Data
The launch of the National Kidney Foundation’s first nationwide registry of patients with kidney disease could help link patient data with laboratory and clinical information.
Anemia in CKD Associated With Lower eGFR, Adverse Outcomes
A cross-sectional study found that severe anemia was common in patients with chronic kidney disease (CKD) and was associated with lower glomerular filtration rate (eGFR) and multiple adverse outcomes.
Heat Exposure Associated With Emergency Visits for Patients With Kidney Disease
An increased risk of emergency department visits for patients with kidney disease was found when patients were exposed to extreme heat.
New eGFR Formula May Inappropriately Label Black Potential Kidney Donors as Having CKD
This study found that the recent change to remove race from the calculation of estimated glomerular filtration rate (eGFR) may incorrectly label potential donors who are Black as having chronic kidney disease (CKD).
Decline in Health Care Services for Patients With CKD Linked to COVID-19 Pandemic
A retrospective observational study found that there was a decline in health care services for patients with chronic kidney disease (CKD) during the early months of the COVID-19 pandemic.
Kidney Transplant Recipients Able to Find Stable Work Post Surgery
A recent report found that 56% of patients from The Netherlands who underwent a kidney transplant were able to work and functioned well while working.
Genomic Testing Could Be More Beneficial for Patients With CKD
Genomic testing can benefit patients with chronic kidney disease (CKD) as more causative genes are identified and evidence for clinical utility is discovered.
Use of Anticoagulants Has Increased for Patients With Atrial Fibrillation, CKD
A recent study found that patients with chronic kidney disease and atrial fibrillation are increasingly using direct oral anticoagulants.
Improved Air Pollution Levels Linked With Less Renal Function Decline During COVID-19 Pandemic
A retrospective cohort study found that a drop in events signaling renal function decline during the COVID-19 pandemic could be associated with a decrease in fine particulate matter concentration.
Low Handgrip Strength, Obesity Associated With Increased Risk of CKD in Women
Post-menopausal women who had dynapenic-abdominal obesity, determined by hand-grip strength and waist circumference, had a higher risk of chronic kidney disease (CKD) compared with controls.
Milken Institute's Sarah Wells Kocsis on How Climate Change, Aging Impact CKD Care
Sarah Wells Kocsis, MBA, is co-author of the Milken Institute report, “Chronic Kidney Disease: Finding a Path to Prevention, Earlier Detection, and Management.” She spoke to The American Journal of Managed Care® about the findings of the report and how they can be incorporated into care for patients with chronic kidney disease (CKD).
SGLT2 Inhibitors, Combination Therapy Needed to Stem the Tide of CKD in Diabetes
Katherine R. Tuttle, MD, FASN, FACP, FNKF, a nephrologist from the University of Washington and Providence Health Care, discussed new consensus guidelines that call for the early use of sodium glucose cotransporter 2 (SGLT2) inhibitors, GLP-1 receptor agonists, and finerenone in the care of patients with both chronic kidney disease (CKD) and diabetes.
Milken Institute's Sarah Wells Kocsis Highlights Key Findings of Her Research on CKD
Largest Medicare Advantage Plans Pay Large Markups for Dialysis, Could Increase Out-of-Pocket Spending
A recent study found that the largest Medicare Advantage plans pay large markups to large dialysis organizations, and these inflated payments could increase out-of-pocket expenses for patients.
As Health Disparities “Weave Their Way Through Hypertension,” New Agents Are on the Way
Coverage from the 2022 Congress of the American Society for Preventive Cardiology (ASPC) in Louisville, Kentucky, featuring 3 experts on aspects of hypertension treatment: Keith C. Ferdinand, MD, of Tulane University School of Medicine; Kim Allan Williams, MD, of the University of Louisville; and George C. Bakris, MD, of the University of Chicago Medicine.
Remote Management of Renal Function May Reduce Mortality, HF Hospitalizations
A new trial has found that patient management through remote means could reduce all-cause mortality and hospitalizations for heart failure (HF) in patients with renal impairment.
Model Suggests Giving Kidneys to Patients on Dialysis a Better Use of Resources
A recent modeling study found that allocating kidneys to patients receiving dialysis was a better use of the organs from a societal perspective compared with giving kidneys to those on a preemptive waiting list.
Frailty Associated With Risk of ESKD, Mortality in Patients With CKD
A retrospective cohort study found that frailty was prevalent in patients with chronic kidney disease (CKD) and that the adverse effects could include end stage kidney disease (ESKD) and mortality.
Lipid Dysregulation Predictive of CKD Risk, Onset
A recent study found that lipid dysregulation was predictive of the risk of chronic kidney disease (CKD) and occurred years before the onset of CKD.
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