Chronic Kidney Disease

The AJMC® Chronic Kidney Disease compendium is a comprehensive resource for clinical news and expert insights on the condition and treatment of loss of kidney function.

Latest News

Several therapies address both CKD and HF simultaneously, including RAS inhibitors, which have been shown to slow CKD progression and reduce HF hospitalizations. | Image credit: Katie Chizhevskaya - stock.adobe.com
Highlighting Interconnected Pathways, Emerging Therapies in CKD and HF

September 10th 2025

As the prevalence of both chronic kidney disease (CKD) and heart failure (HF) increases, therapies targeting shared pathways are one of the most promising strategies to alter the trajectory of these diseases.

The new guideline emphasizes the role of lifestyle behaviors in high blood pressure, recommending that providers help patients set realistic goals. | Image credit: naowarat - stock.adobe.com
Prevention, Early Intervention Highlighted in Updated High Blood Pressure Guidelines

September 4th 2025

Metabolic syndrome changes over time, and previous research has suggested that changes in metabolic syndrome status might be associated with certain health risks. | Image Credit: Aliaksandr Marko - stock.adobe.com
Continuous Metabolic Syndrome Severity Score Linked With CKD Risk

August 27th 2025

Education sessions by nurse educators were widely well-received, especially when they helped patients manage anxiety and provided actionable guidance. | Image Credit: Minerva Studio - stock.adobe.com
Population Health Management Programs in CKD: Promise and Pitfalls

August 22nd 2025

The researchers noted diabetes and hypertension are both modifiable with appropriate management that brings patients to guidelines-based targets. | Image Credit: Crystal light - stock.adobe.com
PCPs Have Unique Opportunity to Detect, Manage CKD

August 14th 2025

More News

woman with face in her hands looking sad
December 17th 2021

Dialysis Modality Influenced Degree of Pandemic-Related Psychological Distress in Patients With CKD

Skylar Jeremias
Patients with chronic kidney disease (CKD) undergoing hemodialysis experienced a greater degree of psychological distress during the COVID-19 pandemic compared with patients treated with peritoneal dialysis, investigators found.
diagram of kidneys over a blue and yellow watercolor background
December 13th 2021

Acute Kidney Injury Episodes Led to Significant Impacts on Physical, Emotional Health

Skylar Jeremias
Patients who have experienced acute kidney injury (AKI) reported experiencing significant impacts on aspects of their physical and emotional health, demonstrating the different ways that AKI episodes influence patients’ health-related quality of life.
Study: Heating Climate Can Lead to Higher Risks of Mortality, Hospitalization in Patients With ESRD
December 9th 2021

Study: Heating Climate Can Lead to Higher Risks of Mortality, Hospitalization in Patients With ESRD

Skylar Jeremias
Rising ambient temperatures were found to be associated with higher risks of all-cause mortality and all-cause hospitalization in patients with end-stage renal disease (ESRD), highlighting the some of the health-related consequences of climate change.
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December 8th 2021

Patients With Diabetes and Chronic Kidney Disease: ACE Inhibitor or ARB Treatment, Medical Costs for Disease Management, and the FINE-CKD Model to Evaluate Economic Value of Finerenone - Participating Faculty

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December 8th 2021

ACE Inhibitor or ARB Treatment Among Patients With Diabetes and Chronic Kidney Disease

Linda F. Fried, MD, MPH Natalia Petruski-Ivleva, PhD Kerstin Folkerts, MSc Niklas Schmedt, DrPH Priscilla Velentgas, PhD Csaba P. Kovesdy, MD
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December 8th 2021

Medical Costs for Managing Chronic Kidney Disease and Related Complications in Patients With Chronic Kidney Disease and Type 2 Diabetes

Keith A. Betts, PhD Jinlin Song, PhD Elizabeth Faust, MBA, MPH Karen Yang, BA Yuxian Du, PhD Sheldon X. Kong, PhD Rakesh Singh, PhD
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December 8th 2021

FINE-CKD Model to Evaluate Economic Value of Finerenone in Patients With Chronic Kidney Disease and Type 2 Diabetes

Michał Pochopień, MSc David Z. I. Cherney, MD, PhD Kerstin Folkerts, MSc Pierre Levy, PhD Aurélie Millier, PhD Stephen Morris, PhD Prabir Roy-Chaudhury, MD, PhD Sean D. Sullivan, PhD Paul Mernagh, MCom
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December 8th 2021

eAppendix: ACE Inhibitor or ARB Treatment Among Patients With Diabetes and Chronic Kidney Disease

Linda F. Fried, MD, MPH Natalia Petruski-Ivleva, PhD Kerstin Folkerts, MSc Niklas Schmedt, DrPH Priscilla Velentgas, PhD Csaba P. Kovesdy, MD
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December 8th 2021

eAppendix: FINE-CKD Model to Evaluate Economic Value of Finerenone in Patients With Chronic Kidney Disease and Type 2 Diabetes

Michał Pochopień, MSc David Z. I. Cherney, MD, PhD Kerstin Folkerts, MSc Pierre Levy, PhD Aurélie Millier, PhD Stephen Morris, PhD Prabir Roy-Chaudhury, MD, PhD Sean D. Sullivan, PhD Paul Mernagh, MCom
woman wearing a mask talking to a doctor over an iPad
December 6th 2021

Views on Telehealth vs In-Person Care Diverge Among Patients With CKD, Clinicians

Skylar Jeremias
Opinions on the effectiveness and usefulness of telehealth services varied among clinicians and older patients with chronic kidney disease (CKD), suggesting that new measures and training programs should be put in place to mitigate disparities and accessibility issues.
green and white pills and a syringe placed onto a paper with "kidney disease" written on it
December 4th 2021

Potential Link Found Between Vitamin D Therapy, Higher Hypercalcemia Risk in CKD

Skylar Jeremias
Patients with chronic kidney disease (CKD) and elevated levels of parathyroid hormone who are treated with active vitamin D therapy experienced significantly higher risks of hypercalcemia, investigators concluded in a meta-analysis.
image of a kidney surrounded by a superimposed over a clip art image of a cog
December 1st 2021

Nomogram Tool Can Predict Risk of CKD in Patients at High Risk of Developing Cardiovascular Disease

Skylar Jeremias
A tool utilizing 5 predictors was found to be reliable at identifying patients at a high risk of cardiovascular disease who were also at risk of developing chronic kidney disease (CKD), potentially allowing providers to implement prevention strategies sooner than ever before.
Abi Sundaramoorthy, MD, MBA.
November 24th 2021

Contributor: Equity, Not Equality, Is Needed to Close Racial Gap in Chronic Kidney Disease Outcomes

Abi Sundaramoorthy, MD, MBA
Improving clinical care is only one element of the 360-degree, holistic treatment that is necessary to achieve patient equity, not equality, in patients with chronic kidney disease. Biology, lifestyle, and socioeconomic status are 3 areas in which inequities often have a particularly negative impact on a carefully constructed care plan.
Robert A. Gabbay, MD, PhD
November 21st 2021

Dr Robert Gabbay Discusses ADA's Efforts to Address Effect of Diabetes on Kidney Disease

Hayden E. Klein
Robert A. Gabbay, MD, PhD, chief scientific and medical officer at the American Diabetes Association (ADA), describes the ADA's efforts to elevate the conversation about the impact of diabetes on kidney disease.
kidney anatomy shown through a computerized model
November 16th 2021

Increased Heart Rate Found to Be Associated With Kidney Function Declines in Transplant Recipients

Skylar Jeremias
Investigators found that increased heart rate correlated with a decline in the ability for the kidneys to function at 48 weeks after a patient receives a kidney transplant, according to results presented at the 2021 American Heart Association Scientific Sessions.
image of a kidney surrounded by computer data
November 8th 2021

AKI Hospitalizations Found to Be Risk Factor for Postdischarge Adverse Events

Skylar Jeremias
Hospitalization for an acute kidney injury (AKI) event was identified as a risk factor for several adverse events after hospital discharge, including hospital readmission and mortality, according to findings presented at Kidney Week 2021.
image of highlighted kidneys with one having a large red mark
November 8th 2021

AMCP Nexus Abstracts Present Findings on Clinical, Financial Burdens Associated With CKD

Skylar Jeremias
Conference abstracts explored the relationship between serum phosphate levels on mortality in patients with chronic kidney disease (CKD) and cost burdens for employers as patients transition to end-stage renal disease.
Daprodustat Shows Favorable Safety in Treating Anemia in CKD With, Without Dialysis
November 6th 2021

Daprodustat Shows Favorable Safety in Treating Anemia in CKD With, Without Dialysis

Allison Inserro
Daprodustat had no increased cardiovascular risk, compared with erythropoiesis stimulating agents (ESAs), in treating anemia in patients with chronic kidney disease (CKD) who were on dialysis and not on dialysis.
computerized image of kidneys
November 3rd 2021

CMS Finalizes Policy to Improve Kidney Care for Low-Income Medicare Patients

Skylar Jeremias
To help close health equity gaps, CMS finalized a rule that will update payment rates and improve incentives for providers to encourage them to increase access to home dialysis and kidney transplants for low-income patients with end-stage renal disease.
Remove Race From Equation Used to Assess Kidney Function, Researchers Say
September 23rd 2021

Remove Race From Equation Used to Assess Kidney Function, Researchers Say

Allison Inserro
Long-awaited reports released Thursday call for eliminating race in estimated glomerular filtration rate equations and point to alternatives in an effort to eliminate disparities in chronic kidney disease.
Graphic of the number 7
August 31st 2021

Analysis Identifies 7 Factors Associated With Mortality in CKD

Jared Kaltwasser
This new analysis aimed to pinpoint more rigorous predictors of mortality, and it was able to identify “excellent” but not “outstanding” ones, according to the investigators.
graphic of kidneys
August 28th 2021

Il-6 Levels, CKD Status Could Identify Patients Needing Anti-Inflammatory Treatment

Gianna Melillo
Research shows higher levels of interleukin 6 in patients with chronic coronary syndrome were associated with an increased risk of cardiovascular events in patients with chronic kidney disease.
ECG alert graphic
August 23rd 2021

AKI Increases Risk of Death Among Hospitalized Patients Who Experience Cardiac Arrest

Jared Kaltwasser
Among patients who suffer an in-hospital cardiac arrest, acute kidney injury (AKI) raised the risk of all-cause in-hospital mortality from about 30% to more than 60%.
Study: Metabolic Syndrome Increases Cardiovascular, Mortality Risk in Patients With CKD
August 19th 2021

Study: Metabolic Syndrome Increases Cardiovascular, Mortality Risk in Patients With CKD

Jared Kaltwasser
A study suggests that for patients with chronic kidney disease (CKD), the more components of metabolic syndrome present, the higher that patient’s risk of adverse cardiovascular outcomes.
Wordy cancer graphic
August 17th 2021

Cancer History May Elevate Kidney Failure Risk

Maggie L. Shaw
This new study from South Korea investigated if patients with cancer could be at potential greater risk of kidney failure and found connections with several cancer types.
kidney
August 13th 2021

Nephrotic Syndrome Linked With End-Stage Kidney Disease, Cardiovascular Issues

Jared Kaltwasser
Patients with nephrotic syndrome were far more likely than healthy controls to suffer end-stage kidney disease, particularly if they had focal segmental glomerulosclerosis or membranous nephropathy.
Lots of spilled pills
August 11th 2021

Potential Greater Mortality Risk From CKD Linked to Polypharmacy

Maggie L. Shaw
Major polypharmacy use was found to increase risk of mortality between 22% and 135% for American adults with chronic kidney disease (CKD) in this subanalysis of data from the REGARDS study.
Hypotension graphic
August 5th 2021

Orthostatic Hypotension Occurs Similarly Among CKD Patients With, Without DNP

Maggie L. Shaw
This recent study compared orthostatic hypotension outcomes among 2 patient populations, both with chronic kidney disease (CKD), who were or were not living with diabetic nephropathy (DNP).
kidney graphic
July 28th 2021

Longer CKD Duration Linked With Taste Dysfunction

Gianna Melillo
New research indicates an association between longer chronic kidney disease duration and taste dysfunction.
Image of doctor holding a kidney
July 25th 2021

Kidney Function Declines Along 4 Distinct Trajectories, Study Finds

Jared Kaltwasser
About 4 in 10 patients with chronic kidney disease will have “early rapid decline,” a trajectory more likely if the patient also has diabetes.
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