Chronic Kidney Disease

The AJMC® Chronic Kidney Disease compendium is a comprehensive resource for clinical news and expert insights on the condition and treatment of loss of kidney function.

Latest News

FDA Approved. | Image Credit: Nirusmee - stock.adobe.com .jpeg
Oxylanthanum Carbonate Fails to Secure FDA Approval for Hyperphosphatemia, CKD

June 30th 2025

FDA issues a complete response letter for oxylanthanum carbonate, a treatment for hyperphosphatemia in patients with chronic kidney disease (CKD) on dialysis.

Woman laying on bed with mobile phone, using medical app | Prostock-studio - stock.adobe.com
Smartphone-Powered CKD Screening Yields 2.5-Fold Increase in Testing, Early Diagnoses

June 27th 2025

Clinical trial researchers interact with data | Image Credit: elenabsl - stock.adobe.com .jpeg
Lorundrostat Yields Promising Results for Treatment of Hypertension in Patients with CKD and Albuminuria

June 20th 2025

Medicine doctor analysis and diagnosis checking health of patient online and testing result with modern virtual interface on laptop with stethoscope in hand, Online Medical global network - ipopba - stock.adobe.com.jpeg
Dual-Biomarker Approach Best for Equitable Kidney Disease Risk Assessment, New Data Find

June 11th 2025

Dialysis nurse | image credit istockphoto.com
Dialysis Outcomes Tied to Nephrologist Facility Quality, Widening Racial Inequities

May 30th 2025

Population Health Management of Chronic Kidney Disease (CKD)

An expert panel discusses chronic kidney disease (CKD), its impact on cardiovascular disease, and the methods of treatment used on the patient populations.

Panel members

More News

Abi Sundaramoorthy, MD, MBA.
November 24th 2021

Contributor: Equity, Not Equality, Is Needed to Close Racial Gap in Chronic Kidney Disease Outcomes

Abi Sundaramoorthy, MD, MBA
Improving clinical care is only one element of the 360-degree, holistic treatment that is necessary to achieve patient equity, not equality, in patients with chronic kidney disease. Biology, lifestyle, and socioeconomic status are 3 areas in which inequities often have a particularly negative impact on a carefully constructed care plan.
Robert A. Gabbay, MD, PhD
November 21st 2021

Dr Robert Gabbay Discusses ADA's Efforts to Address Effect of Diabetes on Kidney Disease

Hayden E. Klein
Robert A. Gabbay, MD, PhD, chief scientific and medical officer at the American Diabetes Association (ADA), describes the ADA's efforts to elevate the conversation about the impact of diabetes on kidney disease.
kidney anatomy shown through a computerized model
November 16th 2021

Increased Heart Rate Found to Be Associated With Kidney Function Declines in Transplant Recipients

Skylar Jeremias
Investigators found that increased heart rate correlated with a decline in the ability for the kidneys to function at 48 weeks after a patient receives a kidney transplant, according to results presented at the 2021 American Heart Association Scientific Sessions.
image of a kidney surrounded by computer data
November 8th 2021

AKI Hospitalizations Found to Be Risk Factor for Postdischarge Adverse Events

Skylar Jeremias
Hospitalization for an acute kidney injury (AKI) event was identified as a risk factor for several adverse events after hospital discharge, including hospital readmission and mortality, according to findings presented at Kidney Week 2021.
image of highlighted kidneys with one having a large red mark
November 8th 2021

AMCP Nexus Abstracts Present Findings on Clinical, Financial Burdens Associated With CKD

Skylar Jeremias
Conference abstracts explored the relationship between serum phosphate levels on mortality in patients with chronic kidney disease (CKD) and cost burdens for employers as patients transition to end-stage renal disease.
Daprodustat Shows Favorable Safety in Treating Anemia in CKD With, Without Dialysis
November 6th 2021

Daprodustat Shows Favorable Safety in Treating Anemia in CKD With, Without Dialysis

Allison Inserro
Daprodustat had no increased cardiovascular risk, compared with erythropoiesis stimulating agents (ESAs), in treating anemia in patients with chronic kidney disease (CKD) who were on dialysis and not on dialysis.
computerized image of kidneys
November 3rd 2021

CMS Finalizes Policy to Improve Kidney Care for Low-Income Medicare Patients

Skylar Jeremias
To help close health equity gaps, CMS finalized a rule that will update payment rates and improve incentives for providers to encourage them to increase access to home dialysis and kidney transplants for low-income patients with end-stage renal disease.
Remove Race From Equation Used to Assess Kidney Function, Researchers Say
September 23rd 2021

Remove Race From Equation Used to Assess Kidney Function, Researchers Say

Allison Inserro
Long-awaited reports released Thursday call for eliminating race in estimated glomerular filtration rate equations and point to alternatives in an effort to eliminate disparities in chronic kidney disease.
Graphic of the number 7
August 31st 2021

Analysis Identifies 7 Factors Associated With Mortality in CKD

Jared Kaltwasser
This new analysis aimed to pinpoint more rigorous predictors of mortality, and it was able to identify “excellent” but not “outstanding” ones, according to the investigators.
graphic of kidneys
August 28th 2021

Il-6 Levels, CKD Status Could Identify Patients Needing Anti-Inflammatory Treatment

Gianna Melillo
Research shows higher levels of interleukin 6 in patients with chronic coronary syndrome were associated with an increased risk of cardiovascular events in patients with chronic kidney disease.
ECG alert graphic
August 23rd 2021

AKI Increases Risk of Death Among Hospitalized Patients Who Experience Cardiac Arrest

Jared Kaltwasser
Among patients who suffer an in-hospital cardiac arrest, acute kidney injury (AKI) raised the risk of all-cause in-hospital mortality from about 30% to more than 60%.
Study: Metabolic Syndrome Increases Cardiovascular, Mortality Risk in Patients With CKD
August 19th 2021

Study: Metabolic Syndrome Increases Cardiovascular, Mortality Risk in Patients With CKD

Jared Kaltwasser
A study suggests that for patients with chronic kidney disease (CKD), the more components of metabolic syndrome present, the higher that patient’s risk of adverse cardiovascular outcomes.
Wordy cancer graphic
August 17th 2021

Cancer History May Elevate Kidney Failure Risk

Maggie L. Shaw
This new study from South Korea investigated if patients with cancer could be at potential greater risk of kidney failure and found connections with several cancer types.
kidney
August 13th 2021

Nephrotic Syndrome Linked With End-Stage Kidney Disease, Cardiovascular Issues

Jared Kaltwasser
Patients with nephrotic syndrome were far more likely than healthy controls to suffer end-stage kidney disease, particularly if they had focal segmental glomerulosclerosis or membranous nephropathy.
Lots of spilled pills
August 11th 2021

Potential Greater Mortality Risk From CKD Linked to Polypharmacy

Maggie L. Shaw
Major polypharmacy use was found to increase risk of mortality between 22% and 135% for American adults with chronic kidney disease (CKD) in this subanalysis of data from the REGARDS study.
Hypotension graphic
August 5th 2021

Orthostatic Hypotension Occurs Similarly Among CKD Patients With, Without DNP

Maggie L. Shaw
This recent study compared orthostatic hypotension outcomes among 2 patient populations, both with chronic kidney disease (CKD), who were or were not living with diabetic nephropathy (DNP).
kidney graphic
July 28th 2021

Longer CKD Duration Linked With Taste Dysfunction

Gianna Melillo
New research indicates an association between longer chronic kidney disease duration and taste dysfunction.
Image of doctor holding a kidney
July 25th 2021

Kidney Function Declines Along 4 Distinct Trajectories, Study Finds

Jared Kaltwasser
About 4 in 10 patients with chronic kidney disease will have “early rapid decline,” a trajectory more likely if the patient also has diabetes.
Hand holding the number 5
July 20th 2021

Panel Recommends 5 Reporting Requirements for Standardizing AKI Definition

Maggie L. Shaw
Inconsistent application and measure of the Kidney Disease Improving Global Outcomes definition of acute kidney injury (AKI) prompted this review, which used a measure of 75% agreement when defining consensus.
Neon-highlighted picture of kidneys
July 18th 2021

Acute Tubular Injury to Kidneys Likely Result of Severe COVID-19 Infection

Maggie L. Shaw
This new study from Japan investigated possible relationships between tubular injury, COVID-19 severity, and inflammatory markers with development of acute kidney injury.
DaVita, Former CEO Indicted for Market Collusion
July 15th 2021

DaVita, Former CEO Indicted for Market Collusion

Mary Caffrey
The dialysis company faces a $100M fine for each of 2 antitrust counts.
FDA approval stamp
July 15th 2021

FDA Approves Kerendia for Patients With CKD Associated With T2D

Lauren Massaro
Positive drug trial results suggest promising outcomes for adult patients with chronic kidney disease (CKD) associated with type 2 diabetes (T2D).
Exome Sequencing Reveals Genetic Origins of Some Kidney Disease Cases
July 12th 2021

Exome Sequencing Reveals Genetic Origins of Some Kidney Disease Cases

Jared Kaltwasser
Exome sequencing of patients with kidney disease and their families identified 17 different monogenetic causes of kidney disease.
Iron Therapy May Help Broader Group of Patients With Kidney Disease
July 10th 2021

Iron Therapy May Help Broader Group of Patients With Kidney Disease

Allison Inserro
A new study says that treating iron deficiency therapy may improve outcomes in patients with chronic kidney disease, even if they don’t have anemia.
pills and syringe
July 9th 2021

Review: SGLT2 Inhibitors Hold Promise in Improving Renal Outcomes

Jared Kaltwasser
Considerable evidence shows sodium-glucose co-transporter-2 inhibitors have cardioprotective benefits, but new research elucidates the ways in which the drugs can also have positive renal impacts.
CMS Targets Health Care Disparities in ESRD Rulemaking for 2022
July 2nd 2021

CMS Targets Health Care Disparities in ESRD Rulemaking for 2022

Allison Inserro
The proposed changes to the payment model for end stage renal disease (ESRD) would make it the first payment model under the CMS Innovation Center to directly address health equity by incentivizing increased rates of home dialysis and kidney transplants.
Jackson Williams, JD
June 27th 2021

Contributor: A More Nuanced View of Dialysis Providers “Gaming the Rules”

Jackson Williams, JD
The math is straightforward: The best way for employers and insurers to avoid paying for dialysis is to invest in preventive care.
Beyond Diabetes: SGLT2 Inhibitors in Heart Failure, CKD, and in Combination With GLP-1 RAs
June 27th 2021

Beyond Diabetes: SGLT2 Inhibitors in Heart Failure, CKD, and in Combination With GLP-1 RAs

Mary Caffrey
How therapeutic advances can address all 3 conditions was the topic of a symposium Friday during the 81st Scientific Sessions of the American Diabetes Association (ADA), “The Intersection of Diabetes, Heart Failure and Kidney Disease: Challenges and New Insights.”
Kidney icon
June 21st 2021

Potential Link Found Between Depression, Kidney Failure

Stephanie Loder
Adults with normal kidney function who have comorbid depression are more likely to experience a decline in kidney function and have mental and physical impairments from that decline.
Many Patients With ESKD Are Not Placed on Kidney Transplant Waitlist Despite Eligibility
June 17th 2021

Many Patients With ESKD Are Not Placed on Kidney Transplant Waitlist Despite Eligibility

Lauren Massaro
Eligible patients who are not waitlisted for kidney transplants lose profound opportunities and are subject to racial and socioeconomic disparities regarding waitlist placement, a study showed.
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