Sleep

This eta-analysis shows sleep variability—not averages—signals psychosis risk, with stage-specific patterns to guide digital biomarkers and care.

The AI model matched or beat expert agreement on sleep arousal scoring, outperforming interscorer reliability across 10 scorers in an independent dataset.

Secondary analysis of the STAR trial finds hypoglossal nerve stimulation cut hypoxic burden by 76.6%, even in some AHI-defined nonresponders.

Longer sleep is linked to lower glycemic variability and reduced deviation risk in adolescents; higher daytime variability predicted shorter subsequent sleep.

An MRI study found hypothalamic atrophy across most subregions in adults with narcolepsy type 1, with the tuberal-inferior region relatively spared.

A new review links coexisting sleep apnea and diabetes to higher stroke risk, poorer recovery, and greater vascular damage.

LXB significantly improved nighttime sleep architecture and daytime symptoms in narcolepsy type 1 and 2, according to phase 4 DUET study results.

A 2-week sleep/light intervention shifted teens’ circadian timing earlier, increasing weeknight sleep by about 47 minutes in a randomized trial.

Inconsistent use and wording of the “Not Better Explained” diagnostic criterion across major sleep disorder classifications may impact diagnostic accuracy, highlighting the need for greater standardization and clarity in clinical frameworks.

Study finds rural Appalachia faces soaring insomnia and sleep apnea, tied to poverty and stress, urging targeted, equity-focused sleep interventions.

Meta-analysis links obstructive sleep apnea to early kidney injury markers, especially in severe OSA and hypertension, highlighting need for renal monitoring.

Systematic review finds sleep disturbances in menopause are highly prevalent and linked to worse QOL, depression, pain, and reduced work productivity.

NHANES data reveal a US sleep crisis: Chronic sleep deprivation gaps tied to education, BMI, and food security, via Blinder-Oaxaca decomposition.

New IQ data show those with idiopathic hypersomnia and narcolepsy retain normal cognitive ability; fatigue, not sleepiness, hits working memory.

CBT for insomnia, especially digital CBT, often saves costs vs no treatment or drugs, while the cost-effectiveness evidence for hypersomnia remains absent.

Low-sodium oxybate (Xywav) reduces excessive sleep and daytime naps in idiopathic hypersomnia, with placebo withdrawal worsening sleep duration and symptoms.

Sleep-focused TNX-102 SL delivered significant benefits in a phase 3 fibromyalgia study.

New research reveals how outdoor nighttime light exposure subtly impacts sleep quality, increasing light sleep duration while affecting deep sleep in complex ways.

Obstructive sleep apnea significantly worsens mental health in older adults, increasing risks of depression and psychological distress over time.

Obstructive sleep apnea may increase Parkinson disease risk, but early CPAP treatment could significantly reduce this risk.

New research reveals that quick sleep onset may lower hypertension risk, challenging traditional views on sleepiness and cardiovascular health.

In case you missed it: the top 5 highlights from the Menopause Society's 2025 Annual Meeting.

Quality improvement programs markedly increase sleep apnea testing in stroke patients, showing effective ways to improve guideline-based care.

Data suggest OSA is an "effect modifier" on the mortality benefit of GLP-1 receptor agonists in patients co-diagnosed with type 2 diabetes.

The efficacy of GLP-1 inhibitors in weight loss has introduced them as a means of also addressing obstructive sleep apnea in sleep medicine.