Sleep

Mark Bleackley, PhD, chief scientific officer of Incannex, discusses in further detail the need for a pharmacotherapy like IHL-42X in obstructive sleep apnea (OSA) and the medication's underlying mechanisms.

Ron Grunstein, MD, PhD, head of sleep and circadian research, Woolcock Institute of Medical Research, details results from the ALKS 2680 trial and the study's next steps.

Mark Bleackley, PhD, chief scientific officer, Incannex, details the progress of the ongoing RePOSA trial, which is assessing the safety and efficacy of IHL-42X in patients with obstructive sleep apnea (OSA).

Michael Thorpy, MD, professor of neurology, Albert Einstein College of Medicine, discusses the hopeful future of treatment in idiopathic hypersomnia.

Michael Thorpy, MD, professor of neurology, Albert Einstein College of Medicine explores the current treatment landscape of idiopathic hypersomnia and the associated challenges with approving new medication for this condition.

A prospective study concluded that patients with narcolepsy can safely switch from a high-sodium oxybate to a low-sodium oxybate to manage their symptoms.

Michael Thorpy, MD, professor of neurology, Albert Einstein College of Medicine, explored the mechanism of action in orexin agonists, which has been indicated for idiopathic hypersomnia.

Melissa Jones, MD, shares insights into recent artificial intelligence (AI) innovations in the realm of sleep studies.

Findings from a retrospective study suggested a possible causal relationship between prior infection and the development of hypersomnolence disorders such as narcolepsy and idiopathic hypersomnia, but more research is needed.

A study assessing adolescents' self-reported sleep behavior and social factors unearthed a relationship between individual popularity and their sleep patterns.

A secondary analysis investigating the efficacy of a digital, interactive cognitive behavioral therapy program for insomnia (CBTi) demonstrated the positive impacts of the program for patients with insomnia or a high risk of co-morbid insomnia and sleep apnea (COMISA).

A recent meta-analysis drew limited conclusions about the impact of 1-night sleep restriction on cognitive function, stressing the need for further research consideration.

A large cohort study demonstrated the validity and reliability of single-channel electro-oculography (EOG) for sleep-stage classification.

The University of Utah Drug Information Service reports an unprecedented rise in shortages; cultural ethos and modern pressures contribute to sleep deprivation across the nation; rising death rates underscore the urgent need for expanded access to prevention and treatment measures

A small, double-blind study has revealed the promise of the BAY2586116 nasal spray to help manage severe forms of obstructive sleep apnea and lower an individual’s morning blood pressure.

A cluster analysis demonstrated the potential for the Multiple Sleep Latency Test (MSLT) to aid in the diagnosis of central hypersomnia and distinguish between idiopathic hypersomnia subgroups.

A cross-sectional study utilizing self-reports from Chinese college students correlated mobile phone use with insomnia, bolstering previous research that made similar conclusions.

A cross-sectional study did not find significant associations between sleep health and consumption of caffeine from coffee or tea in older adults.

A placebo-controlled, double-blind, randomized study suggested that the consumption of yeast mannan may benefit sleep quality and gut health.

A large population-based study revealed the associations between sleep-disordered breathing (SDB) and risk for hypertension and diabetes through the use of metabolomic profiling.

A case-control study finds altered sleep events and characteristics exhibited in elderly patients with epilepsy compared to younger patients with epilepsy, as well as those without.

A bidirectional Mendelian randomization (MR) study found a casual relationship between sleep-related phenotypes (SRPs) and gut microbiota.

Researchers found significant associations between individual patterns and preferences for sleeping and their biological, phenotypical age.

A global analysis of sleep duration and irregularity gathered data on the adult population’s sleep patterns.

A systematic review of randomized controlled trials and prospective cohort studies concludes that sleep could be a prognostic component of lower back pain, but better evidence is needed.