February 2nd 2023
Known to be a contributing factor to polyp development at high levels, periostin’s potential as a biomarker for eosinophilic chronic rhinosinusitis (ECRS) severity was investigated in a new study in which outcomes were compared between patients who had ECRS and those with non-ECRS.
January 25th 2023
January 17th 2023
January 11th 2023
Interleukin-13, Periostin Show Potential as Biomarkers in Prurigo Nodularis
January 7th 2023Levels of certain biomarkers of inflammation in prurigo nodularis were evaluated between patients with and without the chronic inflammatory skin disorder, with the goal of showing potential for precision medicine in prurigo nodularis.
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Risk of EoE Elevated Following Care for Previous Infection
January 6th 2023With previous research showing that having a history of infection can lead to loss of autoimmunity, Swedish researchers set out to investigate a potential link between prior infection and development of eosinophilic esophagitis (EoE).
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Managing GI Symptoms During OIT for Food Allergies
December 16th 2022Though a large proportion of patients receiving oral immunotherapy (OIT) for food allergy report gastrointestinal (GI) symptoms, a knowledge gap remains for the best approach to determine the underlying etiology and manage symptoms.
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Modified Elimination Diet May Be Effective in Children With Eosinophilic Gastrointestinal Disorders
December 15th 2022Based on their retrospective findings, the researchers suggest the diet is a potentially effective option for these patients who may face challenges with other elimination diets.
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BMI Implicated in Glucocorticoid Insensitivity in CRSwNP
November 30th 2022The investigators of this study compared outcomes between patients who had eosinophilic or noneosinophilic chronic rhinosinusitis with nasal polyps (CRSwNP) by comparing the influence of body mass index (BMI) on each disease subtype.
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Exploring Current Eosinophilic Gastrointestinal Disease Nomenclature and Management
November 23rd 2022An article published in the journal Gastroenterology & Hepatology highlights recent updates to eosinophilic gastrointestinal disease nomenclature, as well as updates related to diagnosis, pathogenesis, and treatment standards.
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Disease Characteristics Vary Widely Among Patients With CRSwNP or CRSsNP
November 19th 2022The investigators of this new study wanted to more clearly define the patient characteristics of the 2 main types of chronic rhinosinusitis: with nasal polyps (CRSwNP) and without nasal polyps (CRSsNP).
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Presence of CRS May Indicate Potential to Develop Ulcerative Colitis
November 14th 2022Despite knowledge of chronic rhinosinusitis and inflammatory bowel diseases (IBDs) sharing dysfunctional mucosa, little is known of potential associations between sinusitis and IBD, which prompted this new study.
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Nasal Cytology Produces Comparable Results to Surgery in CRSwNP
November 9th 2022The investigators of a new study evaluated if nasal cytology was a reliable method to identify type 2 inflammation in patients who have chronic rhinosinusitis with nasal polyps (CRSwNP), which could then facilitate patient selection for biological drug utilization via endotypization.
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Patients With Asthma, Other Allergic Diseases May Have Higher Prevalence of EoE
October 18th 2022While the prevalence of eosinophilic esophagitis (EoE) is estimated to be 0.5% in the general population, a recent study found that the prevalence was as high as 16.5% in patients with allergic disease.
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Review Finds Insufficient Evidence Supporting Corticosteroid Irrigation for CRS With Nasal Polyps
October 12th 2022A search of the peer-reviewed literature turned up inconsistent findings on the effectiveness of corticosteroid irrigation for the treatment of chronic rhinosinusitis (CRS) with nasal polyps.
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Periostin as Biomarker May Be More Useful Than Eosinophils in ECRS
October 4th 2022Despite extensive study, eosinophilic chronic rhinosinusitis (ECRS) remains a significant health problem with few effective treatments, so this study compared periostin levels among those who did and did not have ECRS to assess its potential as a disease biomarker.
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