January 25th 2024
The expanded indication makes dupilumab the only approved treatment for eosinophilic esophagitis (EoE) in this age group.
Turning Food Allergy Triggers Into Therapy: A Managed Care Lens on Immunotherapy and Targeted Biologics
1.5 Credits / Immunology
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Targeted Therapies for the Management of Eosinophilic Esophagitis Across the Life Cycle: The Role of the Pharmacist in Patient Identification and Optimization, featuring a Pat...
1.5 Credits / Immunology
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Managed Care Perspectives on the Burden of Food Allergies and Advances in Treatment
1.5 Credits / Allergy, Immunology
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Managing GI Symptoms During OIT for Food Allergies
December 16th 2022Though a large proportion of patients receiving oral immunotherapy (OIT) for food allergy report gastrointestinal (GI) symptoms, a knowledge gap remains for the best approach to determine the underlying etiology and manage symptoms.
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Modified Elimination Diet May Be Effective in Children With Eosinophilic Gastrointestinal Disorders
December 15th 2022Based on their retrospective findings, the researchers suggest the diet is a potentially effective option for these patients who may face challenges with other elimination diets.
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BMI Implicated in Glucocorticoid Insensitivity in CRSwNP
November 30th 2022The investigators of this study compared outcomes between patients who had eosinophilic or noneosinophilic chronic rhinosinusitis with nasal polyps (CRSwNP) by comparing the influence of body mass index (BMI) on each disease subtype.
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Exploring Current Eosinophilic Gastrointestinal Disease Nomenclature and Management
November 23rd 2022An article published in the journal Gastroenterology & Hepatology highlights recent updates to eosinophilic gastrointestinal disease nomenclature, as well as updates related to diagnosis, pathogenesis, and treatment standards.
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Disease Characteristics Vary Widely Among Patients With CRSwNP or CRSsNP
November 19th 2022The investigators of this new study wanted to more clearly define the patient characteristics of the 2 main types of chronic rhinosinusitis: with nasal polyps (CRSwNP) and without nasal polyps (CRSsNP).
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Nasal Cytology Produces Comparable Results to Surgery in CRSwNP
November 9th 2022The investigators of a new study evaluated if nasal cytology was a reliable method to identify type 2 inflammation in patients who have chronic rhinosinusitis with nasal polyps (CRSwNP), which could then facilitate patient selection for biological drug utilization via endotypization.
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Patients With Asthma, Other Allergic Diseases May Have Higher Prevalence of EoE
October 18th 2022While the prevalence of eosinophilic esophagitis (EoE) is estimated to be 0.5% in the general population, a recent study found that the prevalence was as high as 16.5% in patients with allergic disease.
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Review Finds Insufficient Evidence Supporting Corticosteroid Irrigation for CRS With Nasal Polyps
October 12th 2022A search of the peer-reviewed literature turned up inconsistent findings on the effectiveness of corticosteroid irrigation for the treatment of chronic rhinosinusitis (CRS) with nasal polyps.
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Periostin as Biomarker May Be More Useful Than Eosinophils in ECRS
October 4th 2022Despite extensive study, eosinophilic chronic rhinosinusitis (ECRS) remains a significant health problem with few effective treatments, so this study compared periostin levels among those who did and did not have ECRS to assess its potential as a disease biomarker.
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Pediatric ESS Effective, Safe to Treat Chronic Sinusitis With Nasal Polyps
September 28th 2022With a high recurrence rate following surgery to treat chronic sinusitis with nasal polyps, authors set out to investigate the effectiveness and safety of endoscopic sinus surgery (ESS) in a pediatric patient population.
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Examining Biologic-Related Adverse Events in CRS With Nasal Polyps
September 23rd 2022Headaches, injection site reactions, and pharyngitis were the most common adverse events associated with the biologic therapies dupilumab, omalizumab, mepolizumab, and reslizumab in the treatment of chronic rhinosinusitis (CRS) with nasal polyps.
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Researchers Evaluate Racism as a Factor in Underestimation of Atopic Disease
September 15th 2022Although allergic and atopic disease is well studied and researched overall, the researchers said there is a critical lack of knowledge about these conditions, including eosinophilic esophagitis, asthma, and atopic dermatitis, in diverse racial and ethnic groups.
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Risk Factors for CRS Plus Asthma Differ Among Younger vs Older Patients
September 14th 2022Risk factors as predictors of asthma prevalence among a cohort of patients living with chronic rhinosinusitis (CRS), as they related to age, were evaluated by clinical investigators from the College of Medicine at Korea University.
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SCS Use May Predispose Patients Who Have CRSwNP to Worse Health Outcomes
September 9th 2022Using systemic corticosteroids (SCS) to treat chronic rhinosinusitis with nasal polyps (CRSwNP) has been linked to adverse outcomes among patients, prompting these study investigators to compare their health care resource utilization with that of patients who have CRSwNP but don’t use SCS.
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OIT Can Continue Even if EoE Develops, Researchers Say
September 8th 2022A recent study attempted to determine the prevalence of eosinophilic esophagitis (EoE) in a group of patients allergic to milk or egg and undergoing oral immunotherapy (OIT) to those foods, as well as describe its management and treatment pathway.
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