Inflammation

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Higher Weight-Adjusted Waist Index Tied to Greater Mortality Risk in Patients With Osteoarthritis

April 23rd 2025

Researchers consider the weight-adjusted waist index a more precise predictor of mortality risk in patients with osteoarthritis than traditional obesity measures, like body mass index.

"Overactive bladder" written on sticky note | Image Credit: syahrir - stock.adobe.com
Elevated Inflammatory Marker Levels Associated With Increased Overactive Bladder Risk

April 15th 2025

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Inflammatory Diets Raise Risk of Brain Disorders

April 10th 2025

Guselkumab | Image Credit: luchschenF - stock.adobe.com
Guselkumab Shows Sustained Efficacy in Phase 3b APEX Study for Active PsA

April 8th 2025

COPD graphic | Image Credit: Maks_Lab - stock.adobe.com
Systemic Immune Response Index Identified as Independent Risk Factor for COPD

March 23rd 2025

Continuing Medical Education
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April 30th 2025

Emerging Concepts and Approaches in the Treatment of Food Allergy: What Managed Care Professionals Need to Know

1.5 Credits / Immunology, Allergy
April 30th 2025

Innovations in Inflammatory Bowel Disease Therapy: How IL-23 Inhibitors Are Shaping Treatment and Managed Care Approaches

May 20, 2025 | 1:00 PM and 8:00 PM ET
April 30th 2025

Exploring Innovative Approaches in Myasthenia Gravis and the Specialty Pharmacist’s Role in Optimizing Value-Based Treatment

1.5 Credits / Immunology
April 30th 2025

Treatment Gaps in the Management of Generalized Pustular Psoriasis: Enhancing the Role of Managed Care

1.5 Credits / Dermatology, Immunology
April 30th 2025

Advancing Targeted Therapies Aimed at Smoldering Disease in Multiple Sclerosis

1.0 Credit / Immunology, Neurology
April 30th 2025

Managed Care Insights on the Advances in the Eosinophilic Esophagitis Treatment Landscape

1.0 Credit / Gastroenterology, Immunology, Rare Diseases
April 30th 2025

Managing Patients With COPD: Evidence-Based Care and Optimizing Value of New and Emerging Targeted Therapies

1.0 Credit / Immunology, Pulmonology/Respiratory
April 30th 2025

Managed Care Approaches to Individualize Treatment of Hereditary Angioedema

1.0 Credit / Immunology
April 30th 2025

From Strict Avoidance to Tailored Therapies: Transforming Food Allergy Care

1.5 Credits / Allergy, Immunology

More News

Image of skin irritation: Aleksej - stock.adobe.com
March 12th 2023

Cluster Analysis Characterizes 2 Distinct Subsets of Prurigo Nodularis

Jaime Rosenberg
Using a clustering algorithm, researchers were able to identify inflammatory and noninflammatory subsets of the disease, which may account for varying responses to certain treatments.
Graphic representing an FDA investigation | photo credit: wladimir1804 - stock.adobe.com
March 7th 2023

FDA Accepts Application for Dupilumab to Treat Chronic Spontaneous Urticaria

Maggie L. Shaw
The supplemental Biologics License Application was filed for the new indication for dupilumab, which is already approved to treat atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyposis, and eosinophilic esophagitis.
Imaged of inflamed esophagus
March 3rd 2023

Different Elimination Diets Produce Comparable Results in EoE

Maggie L. Shaw
The 2 therapies, a 1-food and a 6-food elimination diet both used for eosinophilic esophagitis (EoE), were compared for outcomes after 6 weeks.
Image representing medical guidance
February 24th 2023

New Guidance Supports 3 Therapies for CRSwNP

Maggie L. Shaw
In this analysis, evidence was reviewed for the effectiveness of intranasal corticosteroids, biologics, and aspirin therapy after desensitization use among patients who have chronic rhinosinusitis with nasal polyposis (CRSwNP).
Image of food with an allergy sign
February 17th 2023

Are Less-Restrictive Diets Possible Among Patients With EoE? Study Says Yes

Maggie L. Shaw
This review and meta-analysis included 34 studies covering 1762 patients, and investigated the efficacy of 4 varieties of dietary treatment for eosinophilic esophagitis (EoE).
Image of an electronic medical record
February 6th 2023

Case Highlights EoE With Dysphagia Despite No Asthma, Atopic Disease History

Jared Kaltwasser
Such cases of eosinophilic esophagitis (EoE) are rare, but they can be treated with the typical therapies for EoE.
Image of inflamed nasal passages
February 2nd 2023

Periostin Bests Eosinophil Count for Biomarker Predictability in ECRS

Maggie L. Shaw
Known to be a contributing factor to polyp development at high levels, periostin’s potential as a biomarker for eosinophilic chronic rhinosinusitis (ECRS) severity was investigated in a new study in which outcomes were compared between patients who had ECRS and those with non-ECRS.
Image of biomarker analysis
January 25th 2023

Biomarkers Indicate Potential Need for Chronic Rhinosinusitis Surgery

Maggie L. Shaw
Outcomes were investigated among 541 patients who had chronic rhinosinusitis; they accounted for 435 primary surgeries and 106 revisionist surgeries.
image of a sick child
January 20th 2023

Early Diagnosis Vital to Prevent Impairment From Pediatric EGIDs

Maggie L. Shaw
Although it is well studied in adult patients, there is a lack of research on eosinophilic gastrointestinal disorders (EGIDs) among pediatric patients; a recent study aimed to add to the clinical knowledge of EGIDs in younger patients.
Image of nasal spray and drops
January 17th 2023

Adherence to Postop Treatment May Indicate Early Recurrence of CRSwNP

Maggie L. Shaw
The utility of and adherence to follow-up exams for potential recurrence of chronic rhinosinusitis with nasal polyps (CRSwNP) was investigated among 60 patients who had undergone functional endoscopic sinus surgery.
Image of PCR test being performed
January 11th 2023

Inflammation Biomarker Potential Investigated in New CRSwNP Study

Maggie L. Shaw
Disease outcomes in chronic rhinosinusitis with nasal polyps (CRSwNP) that related to inflammation and endotype specification were goals in this new study that evaluated the biomarker potential of S100A4.
Image of blood in a test tube
January 7th 2023

Interleukin-13, Periostin Show Potential as Biomarkers in Prurigo Nodularis

Maggie L. Shaw
Levels of certain biomarkers of inflammation in prurigo nodularis were evaluated between patients with and without the chronic inflammatory skin disorder, with the goal of showing potential for precision medicine in prurigo nodularis.
Image of a physician examining a throat
January 6th 2023

Risk of EoE Elevated Following Care for Previous Infection

Maggie L. Shaw
With previous research showing that having a history of infection can lead to loss of autoimmunity, Swedish researchers set out to investigate a potential link between prior infection and development of eosinophilic esophagitis (EoE).
Top 5 Most-Viewed Video Interviews of 2022
December 31st 2022

Top 5 Most-Viewed Video Interviews of 2022

Pearl Steinzor
This year’s top 5 most-viewed videos include topics on eosinophilic esophagitis (EoE), cancer screening awareness, and racial/ethnic and socioeconomic barriers to care.
Graphic representing top 5 nasal polyps articles for 2022
December 28th 2022

Top 5 Most-Read Nasal Polyps Articles of 2022

Maggie L. Shaw
Nasal polyp development, treatment, and recurrence were topics up for discussion in this year’s most popular nasal polyps–related content.
Image of a consultation between a doctor and a patient
December 24th 2022

Charcot-Leyden Crystals Identified as Potential Biomarker for CRSwNP

Maggie L. Shaw
The biomarker potential of Charcot-Leyden crystals in nasal tissue was investigated over 2 years in 110 patients with diagnosed chronic rhinosinusitis with nasal polyps (CRSwNP).
urban scene
December 23rd 2022

Study Examines Effect of Biologics on IgE Levels in Urban Settings

AJMC Staff
This study was prompted by recent findings that ultra-low IgE levels (IgE <2.5 kU/L) may be linked with a higher risk of cancers.
The title as a graphic with health icons
December 21st 2022

Top 5 Most-Viewed EoE Content of 2022

Justina Petrullo
The most-viewed eosinophilic esophagitis (EoE) content of the year covered new developments in treatment options for EoE, the prevalence of EoE in the allergic disease population, and the impact of EoE on a child’s well-being.
Doctor discussing results with patient
December 19th 2022

Improved Voice Quality, Satisfaction Linked to Endoscopic Sinus Surgery

Maggie L. Shaw
This new study, which followed patients up to 6 months after functional endoscopic sinus surgery, evaluated results using objective and subjective measures.
Managing GI Symptoms During OIT for Food Allergies
December 16th 2022

Managing GI Symptoms During OIT for Food Allergies

Jaime Rosenberg
Though a large proportion of patients receiving oral immunotherapy (OIT) for food allergy report gastrointestinal (GI) symptoms, a knowledge gap remains for the best approach to determine the underlying etiology and manage symptoms.
picture of vegetables
December 15th 2022

Modified Elimination Diet May Be Effective in Children With Eosinophilic Gastrointestinal Disorders

Jaime Rosenberg
Based on their retrospective findings, the researchers suggest the diet is a potentially effective option for these patients who may face challenges with other elimination diets.
Man with asthma with doctor
December 5th 2022

Long-term Dupilumab Effective in Patients With Asthma, Including Those With Nasal Polyps

Julia Bonavitacola
Patients with asthma who were with or without a diagnosis of nasal polyps were found to have results with long-term dupilumab.
Stylized obesity word graphic
November 30th 2022

BMI Implicated in Glucocorticoid Insensitivity in CRSwNP

Maggie L. Shaw
The investigators of this study compared outcomes between patients who had eosinophilic or noneosinophilic chronic rhinosinusitis with nasal polyps (CRSwNP) by comparing the influence of body mass index (BMI) on each disease subtype.
Image of chronic rhinosinusitis research
November 28th 2022

Dupilumab Efficacy Confirmed in CRSwNP Subgroup Study

Maggie L. Shaw
Researchers investigated subgroups of patients with chronic rhinosinusitis with polyposis (CRSwNP), wanting more data on their responses to dupilumab and hoping to stratify their level of benefit.
image of food impaction
November 25th 2022

Researchers Use GI Device to Target Early Esophageal Scarring in Pediatric EoE

AJMC Staff
The findings mean that scarring in the esophagus as a result of eosinophilic esophagitis (EoE) can be found earlier, allowing for more targeted intervention.
Abstract image of nasal irritation
November 23rd 2022

Potential Relationship Found Between SERPINB10 Expression, CRSwNP Recurrence

Maggie L. Shaw
This new study explored how expression of SERPINB10 may be related to postoperative recurrence of and inflammation related to chronic rhinosinusitis with nasal polyps (CRSwNP).
Intestines
November 23rd 2022

Exploring Current Eosinophilic Gastrointestinal Disease Nomenclature and Management

Rose McNulty
An article published in the journal Gastroenterology & Hepatology highlights recent updates to eosinophilic gastrointestinal disease nomenclature, as well as updates related to diagnosis, pathogenesis, and treatment standards.
Infection in the blood
November 21st 2022

Previous Infections May Increase Risk of EoE, Study Finds

Jared Kaltwasser
The study findings suggest that eosinophilic esophagitis (EoE), like other atopic diseases, may be associated with infections.
Image of scientific study
November 19th 2022

Disease Characteristics Vary Widely Among Patients With CRSwNP or CRSsNP

Maggie L. Shaw
The investigators of this new study wanted to more clearly define the patient characteristics of the 2 main types of chronic rhinosinusitis: with nasal polyps (CRSwNP) and without nasal polyps (CRSsNP).
Image of a nose under seige
November 9th 2022

Nasal Cytology Produces Comparable Results to Surgery in CRSwNP

Maggie L. Shaw
The investigators of a new study evaluated if nasal cytology was a reliable method to identify type 2 inflammation in patients who have chronic rhinosinusitis with nasal polyps (CRSwNP), which could then facilitate patient selection for biological drug utilization via endotypization.
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