Inflammation

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Higher Weight-Adjusted Waist Index Tied to Greater Mortality Risk in Patients With Osteoarthritis

April 23rd 2025

Researchers consider the weight-adjusted waist index a more precise predictor of mortality risk in patients with osteoarthritis than traditional obesity measures, like body mass index.

"Overactive bladder" written on sticky note | Image Credit: syahrir - stock.adobe.com
Elevated Inflammatory Marker Levels Associated With Increased Overactive Bladder Risk

April 15th 2025

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Inflammatory Diets Raise Risk of Brain Disorders

April 10th 2025

Guselkumab | Image Credit: luchschenF - stock.adobe.com
Guselkumab Shows Sustained Efficacy in Phase 3b APEX Study for Active PsA

April 8th 2025

COPD graphic | Image Credit: Maks_Lab - stock.adobe.com
Systemic Immune Response Index Identified as Independent Risk Factor for COPD

March 23rd 2025

Continuing Medical Education
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April 30th 2025

Emerging Concepts and Approaches in the Treatment of Food Allergy: What Managed Care Professionals Need to Know

1.5 Credits / Immunology, Allergy
April 30th 2025

Innovations in Inflammatory Bowel Disease Therapy: How IL-23 Inhibitors Are Shaping Treatment and Managed Care Approaches

May 20, 2025 | 1:00 PM and 8:00 PM ET
April 30th 2025

Exploring Innovative Approaches in Myasthenia Gravis and the Specialty Pharmacist’s Role in Optimizing Value-Based Treatment

1.5 Credits / Immunology
April 30th 2025

Treatment Gaps in the Management of Generalized Pustular Psoriasis: Enhancing the Role of Managed Care

1.5 Credits / Dermatology, Immunology
April 30th 2025

Advancing Targeted Therapies Aimed at Smoldering Disease in Multiple Sclerosis

1.0 Credit / Immunology, Neurology
April 30th 2025

Managed Care Insights on the Advances in the Eosinophilic Esophagitis Treatment Landscape

1.0 Credit / Gastroenterology, Immunology, Rare Diseases
April 30th 2025

Managing Patients With COPD: Evidence-Based Care and Optimizing Value of New and Emerging Targeted Therapies

1.0 Credit / Immunology, Pulmonology/Respiratory
April 30th 2025

Managed Care Approaches to Individualize Treatment of Hereditary Angioedema

1.0 Credit / Immunology
April 30th 2025

From Strict Avoidance to Tailored Therapies: Transforming Food Allergy Care

1.5 Credits / Allergy, Immunology

More News

Interleukin 6 blood test | Image credit: jarun011 - stock.adobe.com
September 8th 2023

Inflammation Linked With Depression, Reduced Weight Loss After Bariatric Surgery

Kyle Munz
In a longitudinal case study, researchers found that higher inflammation levels may predict poor outcomes following bariatric surgery.
Meta-Analysis Examines Adverse Effects of Low-Dose Glucocorticoids for Rheumatoid Arthritis
September 1st 2023

Meta-Analysis Examines Adverse Effects of Low-Dose Glucocorticoids for Rheumatoid Arthritis

Kyle Munz
Adverse effects associated with glucocorticoid use among patients with rheumatoid arthritis may not be as burdensome as previously indicated.
Nasal inflammation
August 26th 2023

Combining Surgery and Biologic Therapy Improves Outcomes in Patients With CRSwNP

Kyle Munz
Combination endoscopic sinus surgery (ESS) and biological therapy significantly decreased polyp burden in refractory chronic rhinosinusitis with nasal polyposis (CRSwNP) compared with biologic therapy alone
Globe
August 22nd 2023

New Projections for the Global Burden of Osteoarthritis Through 2050

Kyle Munz
Through a series of regression analyses, researchers projected the ever-increasing global burden of osteoarthritis (OA) until 2050.
Knee Joint Pain
August 18th 2023

Novel Scoring System May Better Identify Patients at Risk for Inflammatory Arthritis

Kyle Munz
Researchers analyzed numerous biomarkers in patients at risk for inflammatory arthritis to develop measurable scores indicating a patient's vulnerability to disease progression.
Analyzing Heart
August 12th 2023

Free Myeloperoxidase Levels Show Promise for Predicting Risk of Cardiovascular, All-Cause Mortality

Kyle Munz
New research suggests that measuring the inflammatory marker myeloperoxidase (MPO) may be an effective strategy for the prediction of patients' risk of mortality in a myriad of cardiac—and potentially non-cardiac—diseases.
Pediatrician, consulting and stethoscope for lungs or chest checkup with doctor in medical healthcare hospital or clinic. Medicine, young patient and black man therapist listening to heart of baby: © Nina Lawrenson/peopleimages.com - stock.adobe.com
July 31st 2023

Side-Opening Cutting Forceps Safe, Reliable for Use in Pediatric EoE

Maggie L. Shaw
With data on side-opening cutting forceps showing above a 90% diagnostic rate for tissue biopsy in adult patients with eosinophilic esophagitis (EoE) who undergo biopsy of the esophageal lamina propia (ELP), investigators conducted a pilot study on use of side-opening cutting forceps in younger patients.
Medical Concept: inflammation: © cacaroot - stock.adobe.com
July 28th 2023

Patients With Crohn's Disease Report Low Calcium, Magnesium Intake

Kevin Kunzmann
A study from China suggests calcium and magnesium malnutrition is associated with Crohn's disease inflammation and activity.
Immunoglobulin E (IgE) Test: © luchschenF - stock.adobe.com
July 18th 2023

Clinical Outcomes Poorly Understood Among Rare Subset of Patients With CRS, Immunoglobulin Deficiency

Maggie L. Shaw
The current literature is lacking on outcomes among patients with comorbid chronic rhinosinusitis (CRS) and immunoglobulin deficiencies, especially for those who must use surgery to manage their CRS.
A woman's leg is shown, she is suffering from Chronic Venous Insufficiency with mild cellulitis in her legs. In bed as she rest to relieve heaviness, swelling, pain redness in the leg. Top shot See Less: © Blue - stock.adobe.com
July 15th 2023

Postchemotherapy Pseudocellulitis Needs Defined Diagnostic Criteria

Maggie L. Shaw
With this study, investigators hoped to advance their understanding of cellulitis-mimicking reactions among patients currently receiving chemotherapy.
Asian young woman scratch hand feel suffer from allergy while sleeping: © Kawee - stock.adobe.com
July 13th 2023

Sleep Disturbance Numerical Rating Scale Investigated for Use in Prurigo Nodularis

Maggie L. Shaw
Few validated measures exist to quantify sleep disturbance among patients who have the chronic inflammatory skin condition prurigo nodularis.
Disorders of swallowing, dysphagia. Pharyngeal and esophageal dysphagia. Oral phase. The path of food, the act of swallowing. Person ia x-ray, 3d render: © Naeblys - stock.adobe.com
July 4th 2023

Food Impaction May Be Cause for Concern When Diagnosing EoE

Maggie L. Shaw
Outcomes of concern for this retrospective study were eosinophilic esophagitis (EOE) mucosal biopsies, EoE diagnosis, proton pump inhibitor initiation, and recommendations being followed for repeat esophagogastroduodenoscopy.
medical documents, stethoscope, and pen
June 20th 2023

FeNO Levels Might Have Usefulness in EoE Monitoring

Justina Petrullo
Higher levels of fractional exhaled nitric oxide (FeNO) were found in patients with eosinophilic esophagitis (EoE) and might be able to provide a measurement of clinical treatment response in a subset of these patients.
Questionnaire By Richelle - stock.adobe.com
June 17th 2023

Scientists Identify Treatment Option for Rare Pansclerotic Morphea

Emma Andrus
Scientists have found a new therapy for the severe inflammatory skin disorder.
a graphic of diverse people
June 14th 2023

More Diversity Studies Needed for CRSwNP, CRS Heritability Studies

Justina Petrullo
More geographically and racially diverse population cohorts are needed to determine heritability risk in chronic rhinosinusitis with nasal polyps (CRSwNP) and chronic rhinosinusitis without nasal polyps (CRS).
EOSINOPHILIC ESOPHAGITIS inscription on the sheet: © Yurii Kibalnik - stock.adobe.com
June 9th 2023

Food Elimination Diet Potential Alternative Treatment for EoE

Maggie L. Shaw
Investigators evaluated long-term outcomes among individuals who have eosinophilic esophagitis (EoE) and initiated first-line treatment with a food elimination diet after experiencing remission following stoppage of proton pump inhibitor monotherapy.
Closeup of afro man touches fingers of sore throat, isolated on gray background. Thyroid gland, painful swallowing, tonsillitis, laryngeal swelling concept. Inflammation of the upper respiratory tract: © DimaBerlin - stock.adobe.com
June 2nd 2023

Dupilumab Demonstrates Sustained Improvements in Patients With Eosinophilic Esophagitis

Lana Pine
Regardless of a prior history of swallowed topical corticosteroids, dupilumab was proven to be an effective treatment in patients with eosinophilic esophagitis.
Woman itch hand arm and scratch and have problem with skin,Skincare Concept: © 220 Selfmade studio - stock.adobe.com
May 25th 2023

PRIME, PRIME 2 Data Show 12-, 24-Week Improvements in Patients With Prurigo Nodularis

Maggie L. Shaw
The LIBERTY-PN PRIME and PRIME2 trials investigated itch response to dupilumab among patients who have prurigo nodularis.
Treatment Improves Outcomes in Patients With CRSwNP, Features of Obstructive Lung Disease
May 19th 2023

Treatment Improves Outcomes in Patients With CRSwNP, Features of Obstructive Lung Disease

Rose McNulty
In the phase 3 SINUS-24 and SINUS-52 trials, dupilumab improved clinical outcomes and and health-related quality of life among patients with chronic rhinosinusitis with nasal polyps (CRSwNP) and clinical features of obstructive lung disease.
Patients With EoE Benefit From Systemic Treatment Regardless of Esophageal Dilation History
May 10th 2023

Patients With EoE Benefit From Systemic Treatment Regardless of Esophageal Dilation History

Rose McNulty
Treatment with dupilumab demonstrated improvements in histological markers, symptoms, and endoscopic markers of eosinophilic esophagitis (EoE) regardless of previous history of esophageal dilation.
Medicine doctor with stethoscope in hand and icon insurance for health. Medical network connection on virtual screen interface. Innovation and modern medical technology concept: © ipopba - stock.adobe.com
May 6th 2023

Specialty Tertiary Care for CRSwNP Significantly Improves Patient Outcomes

Maggie L. Shaw
Dupilumab treatment delivered at a specialized tertiary care center has great potential to improve patient clinical outcomes in chronic rhinosinusitis with nasal polyps (CRSwNP).
Nasal Polyps: © freshidea - stock.adobe.com
May 3rd 2023

Biologic Shows Positive Outcomes in CRSwNP Regardless of Baseline Asthma Status

Maggie L. Shaw
Chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma are type 2 inflammatory conditions that frequently coexist, the with the latter increasing the symptom burden of the former
Bronchial or windpipe on the woman body and Bronchitis symptoms: © eddows - stock.adobe.com
April 28th 2023

Distal Esophageal Wall Thickness in EoE Independent of Dysphagia Score, Eosinophil Count

Maggie L. Shaw
Investigators wanted to assess endoscopic appearance, wall thickness, histology, and dysphagia score for eosinophilic esophagitis (EoE).
Man touching his sore throat or neck inflammation: © Glebstock - stock.adobe.com
April 21st 2023

EoE Nonresponders to PPI Treatment May Yet Respond, but More Study Needed

Maggie L. Shaw
A study explored outcomes among patients living with newly diagnosed eosinophilic esophagitis (EoE) who demonstrated lack of histological response following proton pump inhibitor (PPI) treatment.
Quality of life word cloud concept. Vector illustration: © laufer - stock.adobe.com
April 11th 2023

Mental, Physical QOL From CRSwNP Worse vs General Population

Maggie L. Shaw
Health status and health-related quality of life (QOL) outcomes were compared between patients with severe cases of chronic rhinosinusitis with nasal polyps (CRSwNP) and a general patient population.
Study Links Early Pet Exposure, Reduced Food Allergy Incidence in Japanese Children
April 7th 2023

Study Links Early Pet Exposure, Reduced Food Allergy Incidence in Japanese Children

Rose McNulty
Exposure to pets during fetal development or early infancy was associated with reduced instances of food allergies in young children, with different pet exposures potentially reducing the incidence risk of certain allergen types.
Image Credit: © Karolina Grabowska - Pexels
April 6th 2023

Educational Peanut Allergy Intervention Effective in Implementing Prevention Guidelines

Tim Smith
A research letter highlighted recent findings that iREACH educational intervention training may be helpful in preventing peanut allergies.
Elbow, itching: © Aleksej - stock.adobe.com
March 30th 2023

Prurigo Nodularis Improves Following Treatment With Dupilumab

Maggie L. Shaw
Despite the approval of dupilumab (Dupixent) in September 2022, there is an ongoing dearth of clinically effective treatments for prurigo nodularis, prompting the present investigation of the monoclonal antibody for the chronic inflammatory skin condition.
Image of irritated skin: oyoo - stock.adobe.com
March 20th 2023

Patient Outcomes Improve on Several Fronts Following Treatment for Prurigo Nodularis

Maggie L. Shaw
Subanalyses of data from the LIBERTY PN-PRIME and LIBERTY PN-PRIME2 studies illustrate how dupilumab for prurigo nodularis can better patient outcomes, including quality of life and symptom burden.
Image of a digital assessment: WrightStudio - stock.adobe.com
March 16th 2023

Trio of Scales Deemed Valid, Reliable for Use in Prurigo Nodularis

Maggie L. Shaw
The Skin Pain Numeric Rating Scale, Worst-Itch Numeric Rating Scale, and Dermatology Life Quality Index were evaluated for their content validity, fit-for-purpose, and psychometric and measurement properties among patients with the chronic skin disease being treated with dupilumab.
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