Ovarian Cancer

Latest News
August 6th 2025

Patients With Ovarian Cancer, Higher Social Vulnerability Face Delayed Treatment but Earlier Palliative Care Consultations

July 21st 2025

Underuse of Maintenance Therapies Highlights Need for Improved Care Strategies in Advanced Ovarian Cancer

July 13th 2025

Updated OVARIO Trial Results Reinforce Niraparib Plus Bevacizumab Maintenance for Advanced Ovarian Cancer

July 11th 2025

GLP-1 Receptor Agonists Show Promise as Adjunctive Treatment for Ovarian Cancer

July 9th 2025

Disparities Persist Despite Declining US Ovarian Cancer Death Rates

Advancing Ovarian Cancer Treatment: Insights From Emerging Therapies

Discover how advancements in BRCA, folate receptor alpha, HER2, and CCNE1 testing are shaping ovarian cancer care while addressing barriers in education, access, and tumor diversity.

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Video Interviews
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August 3rd 2025

Investigators Call for Greater Awareness, Further Research to Reduce Ovarian Cancer Mortality Disparities

August 1st 2025

Investigators Identify Factors Behind US Ovarian Cancer Mortality Disparities, Propose Targeted Solutions

July 30th 2025

Improved Treatments, Prevention Drive Drop in US Ovarian Cancer Mortality: Muhammad Faizan, MBBS

July 29th 2025

Older, White, and Rural Women Remain at Risk Despite Decline in US Ovarian Cancer Mortality: Muhammad Faizan, MBBS

July 24th 2025

Evaluating Long-Term Safety Considerations for Targeted Therapies in Ovarian Cancer

July 17th 2025

The Effect of Adverse Event Profiles on Treatment Decisions

July 17th 2025

Streamlining Biomarker-Driven Therapy Decisions to Prevent Delays

July 8th 2025

The Importance of Multidisciplinary Collaboration in the Management of Ovarian Cancer

July 8th 2025

Overcoming Payer-Related Barriers for Optimal Care in Patients With Ovarian Cancer

June 10th 2025

ROSELLA Trial Highlights Safe, Biomarker-Free Option for Platinum-Resistant Ovarian Cancer: Brian Slomovitz, MD

Continuing Medical Education
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August 10th 2025

The Economics of Transthyretin-Mediated Amyloidosis: Balancing Equity and Access in Resource Allocation

1 Credit / Cardiology, Neurology
August 10th 2025

Advancing Immunotherapy in Endometrial Cancer: A Managed Care Perspective on Personalized Care

1.5 Credits / Gynecologic Cancer, Health Equity, Diversity & Inclusion, Oncology, Women's Health

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Ovarian cancer | Image Credit: tashatuvango - stock.adobe.com
June 27th 2025

Final PICCOLO Data Highlight Efficacy of Mirvetuximab Soravtansine in Later-Line Frα+ Platinum-Sensitive Ovarian Cancer

Kristi Rosa
Mirvetuximab soravtansine continues to show efficacy and safety in the final analysis of the phase 2 PICCOLO study.
3D illustration of ovarian cancer | Image Credit: Dr_Microbe - stock.adobe.com
June 25th 2025

First-Line Rucaparib Maintenance Reduces Progression Risk Across Prognostic Subgroups in HRD– High-Grade Ovarian Cancer

Chris Ryan
Rucaparib maintenance improved progression-free survival (PFS) in homologous recombination deficiency (HRD)-negative advanced ovarian cancer, irrespective of baseline prognostic factors.
Dr Brian Slomovitz
June 5th 2025

ROSELLA Trial Offers New Insight Into Global Treatment Strategies for Ovarian Cancer: Brian Slomovitz, MD

Brooke McCormick Brian Slomovitz, MD
Brian Slomovitz, MD, of Mount Sinai Medical Center, compares relacorilant plus nab-paclitaxel with existing treatments for platinum-resistant ovarian cancer and highlights the ROSELLA trial’s global scope.
1 expert in this video
June 4th 2025

Learnings From Key Clinical Trials in Ovarian Cancer

Kathleen Moore, MD, MS
Experts explore the evolving landscape of ovarian cancer treatment, emphasizing the need for targeted therapies and biomarker-driven approaches.
1 expert in this video
June 4th 2025

The Potential Impact of Investigational Therapies

Kathleen Moore, MD, MS
Innovative therapies for ovarian cancer, including engineered T cells and antibody-drug conjugates, show promise in improving patient outcomes.
Dr Brian Slomovitz
June 3rd 2025

Relacorilant Plus Nab-Paclitaxel Improves Outcomes in Platinum-Resistant Ovarian Cancer: Brian Slomovitz, MD

Brooke McCormick Brian Slomovitz, MD
Relacorilant combined with nab-paclitaxel (Abraxane) significantly improved progression-free and overall survival in patients with platinum-resistant ovarian cancer in the phase 3 ROSELLA trial, according to Brian Slomovitz, MD, one of the investigators.
Dr CK Wang
June 1st 2025

Ovarian, Breast Cancer Disparities Highlight Need for Better Screening: CK Wang, MD

Brooke McCormick Giuliana Grossi CK Wang, MD
CK Wang, MD, explains that Black women face higher rates of late-stage breast and ovarian cancer diagnoses, demonstrating the need for better screening guidelines and more representative data.
1 expert in this video
May 28th 2025

Single-Agent Vs Combination Regimens

Kathleen Moore, MD, MS
Explore the latest advancements in ovarian cancer treatment, focusing on combination therapies and innovative approaches for platinum-resistant patients.
1 expert in this video
May 28th 2025

Approaching Treatment Sequencing In Heavily Pretreated Patients

Kathleen Moore, MD, MS
Explore the importance of clinical trials for ovarian cancer treatments, highlighting innovative therapies and the need for early patient access.
AAPI written on wooden blocks | Image Credit: Dzmitry - stock.adobe.com
May 27th 2025

Ovarian Cancer Survival Gaps Persist Across Racial, Ethnic Groups

Brooke McCormick
Abstracts published ahead of the 2025 American Society of Clinical Oncology Annual Meeting found persistent ovarian cancer survival disparities among racial and ethnic subgroups, particularly within disaggregated Asian American, Native Hawaiian, and Pacific Islander populations.
1 expert in this video
May 20th 2025

The Use of PARP Inhibitors in Ovarian Cancer

Kathleen Moore, MD, MS
PARP inhibitors revolutionize ovarian cancer treatment, offering targeted therapy options and improved outcomes for patients with specific genetic markers.
1 expert in this video
May 20th 2025

Earlier Introduction of Antibody-Drug Conjugates

Kathleen Moore, MD, MS
Innovative antibody drug conjugates are advancing in ovarian cancer treatment, exploring new maintenance therapies and biomarker-driven approaches for improved outcomes.
Patient consult | Image credit: Adobe Stock
May 18th 2025

Advances in Ovarian Cancer: Using Genomics and Optimizing Maintenance Therapy

Amy VanGalder, PharmD, BCOP
CK Wang, MD, COTA
May 16th 2025

Racial Disparities in Ovarian Cancer Could Increase as Trends Point to Access Barriers: CK Wang, MD

Giuliana Grossi CK Wang, MD
CK Wang, MD, chief medical officer of COTA, highlights how a lack of screening tools and declining ob-gyn pipeline can compound historical disparities seen in Black women's access to care.
Hospital exterior | Image Credit: Spiroview Inc. - stock.adobe.com
May 16th 2025

Access to Minimally Invasive Surgery for Advanced Ovarian Cancer Varies Widely by Facility

Brooke McCormick
Facility-level disparities in adopting minimally invasive interval debulking surgery for ovarian cancer highlight urgent needs for equitable care access.
3D illustration of ovarian cancer | Image Credit: Dr_Microbe - stock.adobe.com
May 13th 2025

Real-World Data Show Bevacizumab Benefits Only High-Risk Patients With Epithelial Ovarian Cancer

Brooke McCormick
In line with previous clinical trial findings, real-world data show that bevacizumab improves outcomes in patients with epithelial ovarian cancer and high-risk prognostic factors.
1 expert in this video
May 13th 2025

The Role of Novel Targeted Therapies

Kathleen Moore, MD, MS
A panelist discusses how novel targeted therapies such as antibody-drug conjugates are rapidly evolving in gynecologic oncology, with multiple agents targeting different biomarkers in development, though optimal sequencing strategies remain to be determined.
1 expert in this video
May 13th 2025

Antibody-Drug Conjugates for Platinum-Resistant Ovarian Cancer

Kathleen Moore, MD, MS
A panelist discusses how antibody-drug conjugates like mirvetuximab should be sequenced in platinum-resistant ovarian cancer, recommending it as first-line therapy for folate receptor alpha–high tumors due to higher response rates when used earlier.
1 expert in this video
May 12th 2025

Improving Clinician Awareness and Adoption of Molecular Testing

Bradley J. Monk, MD, FACS, FACOG
A panelist discusses how guidelines from organizations like the National Comprehensive Cancer Network (NCCN) can improve clinician awareness and adoption of molecular testing in community oncology settings while acknowledging that some effective treatments work across patient populations without requiring biomarker stratification.
1 expert in this video
May 12th 2025

The Impact of Tumor Heterogeneity in Ovarian Cancer

Bradley J. Monk, MD, FACS, FACOG
A panelist discusses how tumor heterogeneity (both spatial and temporal) affects molecular testing reliability in ovarian cancer, highlighting that although most biomarkers show little heterogeneity, newer approaches like liquid biopsies can provide a more comprehensive genetic profile of the entire tumor burden.
women and cancer | Image credit: ST.art - stock.adobe.com
May 11th 2025

Global Analysis Sheds Light on Women’s Cancer Trends

Skylar Jeremias
As National Women’s Health Week approaches, new global data highlighting projected rises in breast and ovarian cancer through 2050 is prompting renewed calls for gender-specific prevention strategies that address evolving health risks for women.
FDA approval graphic | Image Credit: wladimir1804 - stock.adobe.com
May 9th 2025

FDA Approves First Treatment for KRAS-Mutated Recurrent LGSOC

Brooke McCormick
FDA approves the first treatment for KRAS-mutated recurrent low-grade serous ovarian cancer (LGSOC), offering new hope for patients with this condition.
1 expert in this video
May 5th 2025

Comprehensive Molecular Testing in Patients With Ovarian Cancer

Bradley J. Monk, MD, FACS, FACOG
A panelist discusses how education and cost are key challenges in ensuring comprehensive molecular testing is performed in a timely manner for patients with ovarian cancer, emphasizing the need for better education of health care providers and more affordable, widely available testing options.
1 expert in this video
May 5th 2025

Emerging Molecular Biomarkers in Ovarian Cancer

Bradley J. Monk, MD, FACS, FACOG
A panelist discusses how multiple molecular biomarkers beyond BRCA and homologous recombination deficiency (HRD) testing are emerging as important for guiding ovarian cancer therapy, including microsatellite instability (MSI), tumor mutational burden (TMB), HER2, p53, KRAS, and CCNE amplification.
1 expert in this video
April 28th 2025

FRα Biomarker Testing in Patients With Ovarian Cancer

Bradley J. Monk, MD, FACS, FACOG
A panelist discusses how folate receptor alpha (FRα) expression testing plays a crucial role in determining eligibility for mirvetuximab soravtansine (an antibody-drug conjugate therapy), emphasizing the importance of comprehensive biomarker testing at diagnosis rather than piecemeal testing.
1 expert in this video
April 28th 2025

The Role of Guidelines on Molecular Testing in Ovarian Cancer

Bradley J. Monk, MD, FACS, FACOG
A panelist discusses how National Comprehensive Cancer Network (NCCN) guidelines have influenced molecular testing in ovarian cancer, highlighting the importance of biomarkers like BRCA genes for treatment decisions, prognostic information, and family prevention strategies.
female infertility | Image Credit: © dizain-stock.adobe.com
April 27th 2025

No Definitive Link Found Between Female Infertility and Gynecological Cancer

Maggie L. Shaw
New research explores the complex relationship between female infertility and gynecological cancers, revealing minimal links and emphasizing the need for further studies.
BMI graphic | Image Credit: Vitalii Vodolazskyi - stock.adobe.com
April 22nd 2025

Overweight-to-Obese Trajectory in Adulthood May Raise Ovarian Cancer Risk

Brooke McCormick
Individuals who transition from overweight to obese during adulthood may face a higher ovarian cancer risk, highlighting the importance of tracking body fat changes.
CA-125 test | Image Credit: jarun011 - stock.adobe.com
April 17th 2025

Racial Differences in CA-125 Levels Tied to Ovarian Cancer Treatment Delays

Brooke McCormick
Black and American Indian women with ovarian cancer were less likely to have elevated cancer antigen 125 (CA-125) levels at diagnosis, resulting in delayed chemotherapy initiation and highlighting the need for more inclusive guidelines.
Patient taking survey | Image Credit: terovesalainen - stock.adobe.com
April 15th 2025

EHR-Based Symptom Inventory Shows Potential for Ovarian Cancer Monitoring

Brooke McCormick
The electronic health record (EHR)–based symptom inventory identified symptom prevalence and associated comorbidities, but no ovarian cancers were diagnosed during the study period.
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