Parkinson Disease

The AJMC® Parkinson Disease compendium is a comprehensive resource for clinical news and expert insights for progressive nervous system disorder, which affects movement and often includes tremors.

Acupuncture Effective for Anxiety in Patients With Parkinson Disease

September 21st 2022, 6:41pm


Patients with Parkinson disease reported significant reductions in anxiety when provided with acupuncture vs sham acupuncture for 8 weeks.

Pramipexole, Citalopram Effective Therapies for Depression in Parkinson Disease

September 16th 2022, 7:33pm


Patients with Parkinson disease demonstrated significant reduction in depressive symptoms with citalopram and pramipexole, with pramipexole showing slightly more benefit in improving quality of life.

Elevated Incidence of Antipsychotic Use Found Prior to Parkinson Disease Diagnosis

September 10th 2022, 8:30pm


Initiation of antipsychotics was nearly 3 times more common in patients with Parkinson disease vs controls, with the incidence rate found to increase approximately 4 years prior to PD diagnosis.

COVID-19–Related Impact on Physical, Cognitive Symptoms in PD Greater in Lower-Income Countries

September 7th 2022, 12:15pm


Significant worsening of physical and mental symptoms of Parkinson disease was shown in a meta-analysis of diverse patients during the COVID-19 pandemic, with those of lower-income countries shown to be exceptionally vulnerable.

Sleep Abnormalities Linked With Increased PD Risk in Older Men

September 3rd 2022, 1:10pm


Older adults who reported longer total sleep time, lower rapid eye movement (REM) sleep percentage, and higher minimum oxygen saturations during REM sleep had an increased risk of developing Parkinson disease (PD).

Healthy Diet, Exercise Linked With Reduced Mortality Risk in Parkinson Disease

August 22nd 2022, 8:20pm


Patients with Parkinson disease who adhered to a healthy diet pattern and active lifestyle had a lower rate of all-cause mortality than those reporting poor diet quality and lack of physical activity.

Kidney Function Linked With Parkinson Disease Risk in Patients With T2D

August 16th 2022, 4:12pm


Korean patients with type 2 diabetes (T2D) who had reduced levels of estimated glomerular filtration rate and/or proteinuria, 2 hallmarks of diabetic kidney disease, had a greater risk of developing Parkinson disease.

Assessing Risk Factors, Pathophysiology of Freezing of Gait in PD

August 10th 2022, 12:10pm


Freezing of gait incidence among patients with Parkinson disease (PD) was associated with older age, more severe motor symptoms, postural instability/gait difficulty clinical phenotype, and other risk factors.

Deep Brain Stimulation Shown to Improve Anxiety, Depression in PD

August 6th 2022, 3:40pm


Patients with Parkinson disease (PD) exhibited significant improvement in measurement scales for depression and anxiety when treated with subthalamic nucleus deep brain stimulation.

Improved Motor Function Achieved With High- vs Low-Dose Inhaled Levodopa in PD

August 1st 2022, 5:18pm


Significantly more patients with Parkinson disease (PD) achieved improved motor function and clinical outcomes when treated with high- vs low-dose inhaled levodopa.