Parkinson Disease

The AJMC® Parkinson Disease compendium is a comprehensive resource for clinical news and expert insights for progressive nervous system disorder, which affects movement and often includes tremors.

Latest News
February 24th 2023

Air Pollution Linked to PD, With Some Parts of US More Affected Than Others

February 17th 2023

PD Worsens QOL, Increases Depression in Men More Than Women in the Southeast

February 4th 2023

Certain Patient Groups Continue to Be Underrepresented in PD Studies in the Netherlands

February 1st 2023

Creating a Metric to Determine Social Functioning in Parkinson Disease

January 30th 2023

Mindfulness Training May Improve Outcomes for People With Parkinson Disease

Video Interviews
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March 3rd 2021

Implications of Skin Disorders in Parkinson Disease for Neurologists, Dermatologists

February 17th 2021

Unraveling the Mechanisms of Alpha Synuclein in Parkinson Disease

February 5th 2021

Classifying Skin Disorders in Parkinson Disease

January 22nd 2021

Examining the Association, Nature of Skin Disorders in Parkinson Disease

December 1st 2020

How Managed Care Pharmacists Can Improve Current Standards of Treatment for Parkinson Disease

November 19th 2020

Dr Patty Taddei-Allen on Therapeutic Advances in Parkinson Disease

November 11th 2020

A Patient Perspective on Misconceptions, Challenges in Parkinson Disease

October 29th 2020

A Patient Perspective on the Progressive Nature of PD, Impact of Nonmotor Symptoms

October 15th 2020

A Patient Perspective on Early-Onset Parkinson Disease

July 23rd 2020

MJFF COVID-19 Survey Highlights Adverse Implications for Patients With Parkinson Disease

Podcasts
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April 19th 2022

Major Study Expands in Hopes to Cure Parkinson Disease

May 26th 2020

An Inside Look at Innovations by MJFF to Assist the Parkinson Community Amid the COVID-19 Pandemic

July 7th 2019

Podcast: This Week in Managed Care—The Top Managed Care News From the First Half of 2019

May 21st 2019

Improving Care for Patients With Parkinson Disease in the Hospital

More News

Older person walking
January 20th 2023

Motor Symptoms May Occur 3 Years Before Parkinson Disease Diagnosis, Study Says

Allison Inserro
Trouble with balance and holding objects above one's head were just a few of the problems reported by patients 3 years before they received a formal Parkinson disease diagnosis, according to a recent study.
image of mental state
January 8th 2023

Mortality Rates Lower for Patients With PD Using Pimavanserin

AJMC Staff
Compared with patients using other antipsychotics, patients with Parkinson disease using pimavanserin had lower death rates.
Top 5 Parkinson disease articles.
December 29th 2022

Top 5 Most-Read Parkinson Disease Articles of 2022

Matthew Gavidia
The top 5 most-read articles in Parkinson disease for 2022 reviewed interventions for nonmotor symptoms, the health-related impact of exercise and diet, and more.
Person in a wheelchair.
December 20th 2022

Parkinson Disease Incidence Substantially Greater Than Previously Reported, Study Shows

Matthew Gavidia
Incidence of Parkinson disease in North America was 50% higher than previous estimates of 60,000 diagnoses annually.
Senior woman.
December 17th 2022

Combination Therapy Shown to Reduce Risk of Lower Urinary Tract Infection in Patients With Parkinson Disease

Matthew Gavidia
The combination therapy of levodopa and benserazide was associated with a significantly reduced risk of lower urinary tract infections, particularly among women, when compared with another Parkinson disease combination therapy of levodopa and carbidopa.
food.
December 12th 2022

Improved Patient-Reported Outcomes Shown With Mediterranean Diet in Parkinson Disease

Matthew Gavidia
Patients with Parkinson disease who adhered to Mediterranean (MEDI) and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diets were associated with fewer patient-reported symptoms over time, in which the MIND diet showed greater reductions in symptom severity compared with MEDI.
Patient holding hand of physician.
December 7th 2022

Assessing Frequency of Orthostatic Hypotension in Patients With Parkinson Disease

Matthew Gavidia
Frequency of orthostatic hypotension among Ethiopian patients with Parkinson disease (PD) was shown to be higher than that among healthy controls, with a higher proportion of constipation, urinary urgency, and nocturia symptoms reported in those with PD.
stomach bowels.
December 1st 2022

Gastrointestinal Biopsy May Determine Risk of Neurodegenerative Disease

Matthew Gavidia
People with a gastrointestinal biopsy of normal mucosa or nonspecific inflammation were shown to be at increased risk of Alzheimer disease and Parkinson disease.
parkinson.
November 25th 2022

Long-term Pioglitazone Use May Reduce Risk of Parkinson Disease in Patients With Diabetes

Matthew Gavidia
Findings of a meta-analysis show that pioglitazone use with a dose duration greater than 438 days was associated with a significantly reduced risk of Parkinson disease in patients with diabetes.
air pollution.
November 16th 2022

Incidence and Severity of Neurologic Diseases Worsening Due to Air Pollution, Climate Change

Matthew Gavidia
Climate change and exposure to airborne pollutants was associated with incidence and exacerbation of several neurologic diseases, including migraine, dementia, and Parkinson disease.
person in wheel chair.
November 10th 2022

Simvastatin Ineffective as Disease-Modifying Therapy for Intermediate Parkinson Disease

Matthew Gavidia
Patients with intermediate and mild Parkinson disease, defined by a Hoehn & Yahr stage of 3 or less, experienced an additional deterioration in motor function with simvastatin compared with placebo while not taking medication at 24 months.
Man with parkinson-related tremor.
November 9th 2022

Examining Risk Factors, Prodromal Features of Parkinson Disease

Matthew Gavidia
Several known risk factors and prodromal features were associated with Parkinson disease, including traumatic brain injury and alcohol misuse, along with other comorbidities such as skin and gastrointestinal disorders.
health care cost.
November 2nd 2022

Intermediate Parkinson Disease Associated With Significant Clinical, Economic Burden

Matthew Gavidia
A poster presented at Academy of Managed Care Pharmacy Nexus 2022 shows that patients with intermediate Parkinson disease place a significant resource burden on the US health care system in regard to treatment, emergency department visits, and admissions to rehabilitation centers.
Young adults.
October 28th 2022

Assessing Unmet Needs in Care Management of Young-Onset Parkinson Disease

Matthew Gavidia
Patients with young-onset Parkinson disease experience significant emotional burden that is exacerbated by unmet educational needs.
caregiver and patient.
October 24th 2022

Evaluating Impact of COVID-19 Pandemic on Informal Caregivers of Patients With Parkinson Disease

Matthew Gavidia
Informal caregivers of people with Parkinson disease residing in the United Kingdom discussed challenges faced in providing care during the COVID-19 pandemic, which included risk of infection, lack of access to care, and the impact of lockdown on engaging in activities of daily living.
older people.
October 18th 2022

Cataract Surgery More Common in Patients With Parkinson Disease Prior to Diagnosis

Matthew Gavidia
Patients with Parkinson disease (PD) from Finland reported a higher incidence rate of cataract surgeries prior to PD diagnosis vs those without the condition, potentially due to other eye diseases and prodromal symptoms of PD.
senior walking.
October 17th 2022

Vestibular Dysfunction Linked With Abnormal Balance in Parkinson Disease

Matthew Gavidia
Vestibular dysfunction was shown to be a determinant of imbalance in Parkinson disease independent from visual and somatosensory processing changes and nigrostriatal dopaminergic losses.
Asian elderly man.
October 7th 2022

Fracture Risk Increases With Severity of Parkinson Disease

Matthew Gavidia
Patients with Parkinson disease are significantly more likely to experience fractures than the general population, with severity of the disease shown to be linearly associated with risk.
cycling.
October 3rd 2022

Community-Based Cycling Program Shows Positive Impact on Symptom Management in Parkinson Disease

Matthew Gavidia
Location, cost, and transportation were cited as important factors regarding adherence and satisfaction with community-based exercise programs among patients with Parkinson disease.
older couple.
September 28th 2022

Square-Stepping Exercise Linked With Improved Executive Functioning in Parkinson Disease

Matthew Gavidia
Adherence to 8-week square-stepping exercise training among patients with Parkinson disease was associated with significant improvement of executive functioning, as well as cognitive functioning for those with mild cognitive impairment.
Parkinson.
September 21st 2022

Acupuncture Effective for Anxiety in Patients With Parkinson Disease

Matthew Gavidia
Patients with Parkinson disease reported significant reductions in anxiety when provided with acupuncture vs sham acupuncture for 8 weeks.
older man.
September 16th 2022

Pramipexole, Citalopram Effective Therapies for Depression in Parkinson Disease

Matthew Gavidia
Patients with Parkinson disease demonstrated significant reduction in depressive symptoms with citalopram and pramipexole, with pramipexole showing slightly more benefit in improving quality of life.
brain.
September 10th 2022

Elevated Incidence of Antipsychotic Use Found Prior to Parkinson Disease Diagnosis

Matthew Gavidia
Initiation of antipsychotics was nearly 3 times more common in patients with Parkinson disease vs controls, with the incidence rate found to increase approximately 4 years prior to PD diagnosis.
Patient with parkinson disease in wheelchair.
September 7th 2022

COVID-19–Related Impact on Physical, Cognitive Symptoms in PD Greater in Lower-Income Countries

Matthew Gavidia
Significant worsening of physical and mental symptoms of Parkinson disease was shown in a meta-analysis of diverse patients during the COVID-19 pandemic, with those of lower-income countries shown to be exceptionally vulnerable.
Sleep Abnormalities Linked With Increased PD Risk in Older Men
September 3rd 2022

Sleep Abnormalities Linked With Increased PD Risk in Older Men

Matthew Gavidia
Older adults who reported longer total sleep time, lower rapid eye movement (REM) sleep percentage, and higher minimum oxygen saturations during REM sleep had an increased risk of developing Parkinson disease (PD).
exercise.
August 22nd 2022

Healthy Diet, Exercise Linked With Reduced Mortality Risk in Parkinson Disease

Matthew Gavidia
Patients with Parkinson disease who adhered to a healthy diet pattern and active lifestyle had a lower rate of all-cause mortality than those reporting poor diet quality and lack of physical activity.
kidneys.
August 16th 2022

Kidney Function Linked With Parkinson Disease Risk in Patients With T2D

Matthew Gavidia
Korean patients with type 2 diabetes (T2D) who had reduced levels of estimated glomerular filtration rate and/or proteinuria, 2 hallmarks of diabetic kidney disease, had a greater risk of developing Parkinson disease.
caregiver and man on wheelchair.
August 10th 2022

Assessing Risk Factors, Pathophysiology of Freezing of Gait in PD

Matthew Gavidia
Freezing of gait incidence among patients with Parkinson disease (PD) was associated with older age, more severe motor symptoms, postural instability/gait difficulty clinical phenotype, and other risk factors.
brain.
August 6th 2022

Deep Brain Stimulation Shown to Improve Anxiety, Depression in PD

Matthew Gavidia
Patients with Parkinson disease (PD) exhibited significant improvement in measurement scales for depression and anxiety when treated with subthalamic nucleus deep brain stimulation.
Elderly hands.
August 1st 2022

Improved Motor Function Achieved With High- vs Low-Dose Inhaled Levodopa in PD

Matthew Gavidia
Significantly more patients with Parkinson disease (PD) achieved improved motor function and clinical outcomes when treated with high- vs low-dose inhaled levodopa.
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