The AJMC® Parkinson Disease compendium is a comprehensive resource for clinical news and expert insights for progressive nervous system disorder, which affects movement and often includes tremors.
Examining Consequences of Levodopa’s Iron-Binding Ability in PD
Researchers think they know more about why levodopa, the first-line therapy for treating the motor symptoms of Parkinson disease (PD), loses efficacy and causes dyskinesia, or off periods, the longer a patient stays on it.
Cognitive Rehabilitation in PD Helpful but Needs to be Tailored, Review Says
A recently published meta-analysis examined the extent to which cognitive rehabilitation is useful in Parkinson disease (PD), since other reports on the matter have been mixed.
Safinamide May Reduce Nonmotor Symptoms in PD, Study Says
Safinamide belongs to a class of drugs called monoamine oxidase type B inhibitors and is used in conjunction with levodopa to manage OFF periods.
Berries, Red Wine Linked to Longer Survival in Patients With Parkinson Disease
People with Parkinson disease who regularly consumed flavonoids like berries, red wine, tea, and apples had lower rates of death than people who didn’t, according to a new study.
Report Examines Extent of Disruption of Health Services for Patients With PD, Dementia in Ontario
Researchers said they wanted to take a broad look at the level and scope of the disruption for those with Parkinson disease and dementia still living at home and compare the findings to before the pandemic.
Exploring Attitudes Toward Medication Management, Caregiving in Parkinson Disease
Researchers wanted to understand more about the impact of medication management and other quality-of-life issues related to this neurological disease on both patients and caregivers.
Different Pathogeneses May Cause Dementia in Older, Younger Patients With PD
Older patients with Parkinson disease (PD) were found to have a higher incidence of dementia compared with younger patients. However, the difference may have to do with different pathologies causing dementia in older and younger patients.
Some Genes May Alter Cognition in Parkinson Disease More Than Others
A recent review suggests that some genes may influence the severity of cognition impairment in Parkinson disease.
Flu May Be Linked to Increased Risk of Parkinson Disease, Danish Study Finds
A case-control study from Denmark suggests that having influenza may increase the risk of Parkinson disease more than a decade later.
Researchers Use fMRI to Examine Neuroplasticity in Dysphagia Caused by PD
Researchers sought to examine the effect on corresponding regions of the brain after patients with Parkinson disease (PD) and swallowing problems underwent functional magnetic resonance imaging (fMRI) after receiving 10 sessions of repetitive transcranial magnetic stimulation.
Top 5 Most-Read Parkinson Disease Articles of 2021
The top 5 most-read Parkinson disease articles of 2021 explored some of the new tactics being used to manage the disease, such as herbal tea, acupuncture, wearable tech, and cannabis.
Parkinson Disease Lengthens ICU Stays, but Does Not Increase Mortality
A new study comparing intensive care unit stays among patients with Parkinson disease and controls without the disease found the former have more severe illness, but both groups have similar survival rates.
Regular Exercise Linked to Lower All-Cause Mortality in PD
Until now, researchers have not quantified the impact of regular exercise on death for any reason in patients with Parkinson disease (PD).
Research Examines Role of Caffeine, Aspirin, Tobacco in PD
The preliminary analysis, appearing in a preprint journal, looked at lifestyle habits of those with Parkinson disease.
Using AI to Detect Early Signs of Parkinson Disease Through Facial Analysis
Researchers at the University of Rochester are analyzing facial muscle movements through videos taken over webcams or smartphones to train a machine learning algorithm with the hope that it can predict Parkinson disease at an earlier stage.
Defining the Characteristics of Mild Cognitive Impairment in Prodromal PD
Mild cognitive impairment has been proposed as a marker for the prodromal phase of Parkinson disease (PD), but little is known about its presentation in community-dwelling older adults.
Review Suggests Having IBD May Increase Risk of PD
The meta-analysis sought to clarify previous research, which has explored the idea that Parkinson disease (PD) is tied to inflammation in the gastrointestinal tract, noting that inflammatory bowel disease (IBD) has been implicated in neuroinflammation.
Review: Neuroprotective, Multimodal Treatment Needed Against Parkinson Disease
Treatment strategies focused on dopaminergic regeneration rather than symptomatic relief may transform the way Parkinson disease is managed.
Guideline for Treating Motor Symptoms of PD Gets First Update Since 2002
The guideline reflects findings regarding confidence in evidence about how to care for the motor symptoms in patients with early Parkinson disease (PD), including the comparative efficacy of treatments as well as the comparative risk of adverse events.
Latest News in Parkinson Disease: Preoperative RBD Not Linked to Worse Outcomes, Postmortem White Matter, and More
An overview of the latest clinical news in Parkinson disease reported across MJH Life Sciences™.
What Factors Influence Place of Death for Patients With PD, MS?
Recent research from the United Kingdom sought to understand more about factors that may impact the location of death for patients with Parkinson disease (PD) and multiple sclerosis (MS).
Does Having Sleep Apnea Matter Prior to Deep Brain Stimulation in Parkinson Disease?
In this new study, researchers examined 50 patients with PD, including 22 with sleep apnea and 28 without; patients were examined both before and after deep brain stimulation.
Results Point to Need for Ways to Manage Social Anxiety That Accompanies Parkinson Disease
Researchers found that the degree to which a person with idiopathic Parkinson disease engages in these avoidance tactics—such as putting a hand in the pocket to hide a tremor—is moderately predictive of social anxiety. The trouble is, such strategies may make anxiety worse, and patients can develop social anxiety disorder.
Survey Describes How Patients Think, Talk About OFF Periods in Parkinson
Responses from the Fox Insight study describe how patients with Parkinson disease experience OFF periods as expressed in both motor and nonmotor symptoms.
Large Study Finds Parkinson Disease US Death Rate Soared 63% Over 20 Years
The authors said long-term trends in Parkinson disease were previously unknown and that the findings are important to determining national health care priorities.
Can DBS for Parkinson Disease Become More Targeted?
Researchers hope that the benefits seen in a new protocol for deep brain stimulation (DBS) in Parkinsonian mice will extend to humans.
Minor Hallucinations Common, Impactful in Parkinson Disease
More than 1 in 3 patients with Parkinson disease were found to experience minor hallucinations, which were linked with worse quality of life and poor sleep outcomes.
Measuring IADLs in Patients With, Without PD and MCI
Mild cognitive impairment (MCI) affects older adults both with and without Parkinson disease (PD) and can impair the ability to participate in activities of daily living (IADL); a recent study sought to determine how both groups performed, compared with healthy adults, according to 4 measurements.
MJFF Says Work Is Needed to Improve Health Equity in PD
Current knowledge about how Parkinson disease (PD) affects patients from different socioeconomic or ethnic groups is lacking, said The Michael J. Fox Foundation for Parkinson’s Research (MJFF), and diverse groups are underrepresented in research.
Future Parkinson Disease Stage May Be Predictable by Present Low HRQOL
This follow-up study of patients first analyzed 10 years ago sought to determine if health-related quality of life (HRQOL) was still a reliable predictor of Parkinson disease severity, especially at it relates to Hoehn-Yahr stage increase.
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