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Researchers Outline Novel Treatment Approaches Being Studied in Myelofibrosis
October 24, 2020 12:00pm
Their study outlines several treatments being investigated for the treatment of patients with myelofibrosis and other myeloproliferative neoplasms, generally after they have become resistant or intolerant to Janus kinase inhibition.
Dr Lametra Scott Discusses Cost, Formulary Guidance in Managing Sickle Cell Disease
October 23, 2020 08:42pm
Areas to Watch in Specialty Drug Pipeline Include Cancer, Orphan Drugs
October 23, 2020
Article
In her presentation, Aimee Tharaldson, PhD, senior clinical pharmacist of emerging therapeutics at Express Scripts, discussed the upcoming pipeline of specialty drug approvals and their potential impact on the market.
Dr Aimee Tharaldson Outlines the Pipeline, Role of Emerging Specialty Medications
October 23, 2020
Video
In the current pipeline of specialty medications seeking approval, a majority of development lies within orphan drugs and cancer medications, said Aimee Tharaldson, PharmD, of Express Scripts.
Cancers of Unknown Primary Site May Benefit From NGS Profiling
October 23, 2020
Article
The study describes how RNA sequencing and DNA sequencing for selected genes were performed simultaneously to evaluate gene expression and alterations in order to predict tumor origin.
Study Highlights Importance of Swift SMA Diagnosis Through Use of Newborn, Carrier Screening
October 23, 2020
Article
A new study is underscoring the importance of diagnostic testing for patients with spinal muscular atrophy (SMA) to ensure early diagnosis of the disease.
Pembrolizumab Plus Radiation Therapy Improves NSCLC Outcomes, Study Finds
October 23, 2020
Article
Researchers analyzed 2 randomized studies to learn how adding radiation therapy to pembrolizumab immunotherapy affects non-small cell lung cancer patient outcomes.
Sacubitril/Valsartan Has Possible Economic Benefit When Administered in a Hospital Setting to Patients With HFrEF
October 23, 2020
Article
Heart failure with reduced ejection fraction (HFrEF) is when the heart’s left ventricle can only pump out 40% or less of the blood it contains, resulting in less oxygen-rich blood being disseminated to the body than it actually needs.
What Drives Leukemic Transformation of Polycythemia Vera, Essential Thrombocythemia?
October 23, 2020
Article
New findings from a small study are suggesting that time to leukemic transformation may be driven by distinct time-dependent molecular mechanisms.
Akebia Therapeutics' CEO on Mechanisms of HIF-PHI Candidate
October 23, 2020
Video
Vadadustat is an investigational drug belonging to a class known as hypoxia-inducible prolyl hydroxylase inhibitors (HIF-PHIs) for the treatment of anemia in chronic kidney disease.
Dr Rajiv Agarwal Discusses Finerenone, Results of FIDELIO-DKD
October 23, 2020
Video
The investigational drug finerenone met its primary endpoint in FIDELIO-DKD of slowing progression of chronic kidney disease (CKD) in patients with type 2 diabetes and CKD, said Rajiv Agarwal, MD, MS, FASN, a professor of medicine at Indiana University School of Medicine and a staff physician at the Veterans Affairs Medical Center in Indianapolis, Indiana.
Dr Michael Green Discusses Understanding Patient Response to CAR T-Cell Therapy
October 23, 2020
Video
Chimeric antigen receptor (CAR) T-cell therapy does not always lead to a durable response, and we are trying to figure out why, noted Michael R. Green, PhD, University of Texas MD Anderson Cancer Center.