Inflammation

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patient suffering from rheumatoid arthritis | Image Credit: doucefleur - stock.adobe.com
Real-World Evidence Confirms the Benefits of JAK Inhibitors in Patients With Rheumatoid Arthritis

January 16th 2025

This systematic review of real-world observational studies demonstrated the effectiveness of Janus kinase (JAK) inhibitors in improving treatment adherence, persistence, clinical outcomes, and patient-reported outcomes among US patients with rheumatoid arthritis.

Doctor presenting brain model and medication | Image Credit: Nadzeya - stock.adobe.com
Early Onset Active IBD Linked to Higher Rates of Psychiatric Disorders, Medication Use

January 12th 2025

Nurse helping female patient | Image Credit: Rido - stock.adobe.com
Nurse-Led Care Improves Disease Activity in Rheumatoid Arthritis

January 8th 2025

Doctor holding a card that says "eosinophilic esophagitis" | Image Credit: Yurii Kibalnik - stock.adobe.com
Male Patients With Eosinophilic Esophagitis Face Higher Complication Rates

January 6th 2025

Red FDA approval stamp | image credit: chrisdorney - stock.adobe.com
FDA Approves Dupilumab to Treat EoE for Children Under 12 Years

January 25th 2024

Recommended Guidelines and Restrictions in Asthma

Defining the recommended guidelines and the formulary restrictions with the standard of care for asthma.

Use of Biologics for the Treatment of Asthma panelists
Continuing Medical Education
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January 20th 2025

Emerging Concepts and Approaches in the Treatment of Food Allergy: What Managed Care Professionals Need to Know

1.5 Credits / Immunology, Allergy
January 20th 2025

Exploring Innovative Approaches in Myasthenia Gravis and the Specialty Pharmacist’s Role in Optimizing Value-Based Treatment

1.5 Credits / Immunology
January 20th 2025

Treatment Gaps in the Management of Generalized Pustular Psoriasis: Enhancing the Role of Managed Care

1.5 Credits / Dermatology, Immunology
January 20th 2025

Advancing Targeted Therapies Aimed at Smoldering Disease in Multiple Sclerosis

1.0 Credit / Immunology, Neurology
January 20th 2025

Managed Care Insights on the Advances in the Eosinophilic Esophagitis Treatment Landscape

1.0 Credit / Gastroenterology, Immunology, Rare Diseases
January 20th 2025

Managing Patients With COPD: Evidence-Based Care and Optimizing Value of New and Emerging Targeted Therapies

1.0 Credit / Immunology, Pulmonology/Respiratory
January 20th 2025

Managed Care Approaches to Individualize Treatment of Hereditary Angioedema

1.0 Credit / Immunology
January 20th 2025

From Strict Avoidance to Tailored Therapies: Transforming Food Allergy Care

1.5 Credits / Allergy, Immunology

More News

David Pariser, MD
December 18th 2020

Dr David Pariser Outlines Unmet Needs in Treatment Options for Atopic Dermatitis

The treatment landscape for atopic dermatitis is beginning to change from the use of topical therapies to biologics and more, said David Pariser, MD, senior physician at Pariser Dermatology Specialists and professor at Eastern Virginia Medical School Department of Dermatology.
Older Adults Are Often Excluded From RCTs of Systemic Treatments for Atopic Dermatitis
December 17th 2020

Older Adults Are Often Excluded From RCTs of Systemic Treatments for Atopic Dermatitis

Laura Joszt, MA
Older adults are often at greater risk for adverse events from treatments, but they can also be excluded from randomized controlled trials (RCTs), making it difficult to know if findings are generalizable to this population.
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December 11th 2020

Guideline-Informed Care Among Medicaid-Enrolled Children With Food Allergy

Madeleine K. Kanaley, BA Ashley A. Dyer, MPH Olivia R. Negris, MA Jamie L. Fierstein, PhD Christina E. Ciaccio, MD, MSc Ruchi S. Gupta, MD, MPH Lucy A. Bilaver, PhD
This article describes food allergy–related service utilization and identifies factors associated with guideline-informed care among Medicaid-enrolled US children with food allergy.
Child using inhaler
December 10th 2020

Registry for Children With Severe Asthma Shows Potential in Aiding Drug Trial Design

Skylar Jeremias
Investigators concluded that use of a new registry could aid in the recruitment of pediatric subjects with severe asthma and the design of future clinical trials for emerging biologics.
David Pariser, MD
December 10th 2020

Dr David Pariser Highlights Comorbidities and Treatments in the Pipeline for Atopic Dermatitis

The comorbidities associated with atopic dermatitis can be substantial, and the disease can have a significant burden on quality of life, but new biologics and other future treatments may help, said David Pariser, MD, senior physician at Pariser Dermatology Specialists.
David Pariser, MD
December 5th 2020

Dr David Pariser Discusses the Significant Burden of Atopic Dermatitis

The financial, physical, and social burdens of atopic dermatitis can be substantial, especially for patients who had the condition as children into adulthood, said David Pariser, MD, senior physician at Pariser Dermatology Specialists and professor at Eastern Virginia Medical School Department of Dermatology.
National Asthma Guidelines Get First Update in 13 Years
December 4th 2020

National Asthma Guidelines Get First Update in 13 Years

Laura Joszt, MA
Updated guidance in 6 key areas of asthma care focus on improving diagnosis, management, and treatment.
David Pariser, MD
November 28th 2020

Dr David Pariser Outlines Future Treatment Options of Atopic Dermatitis With Biologics and JAK Inhibitors

As the only biologic on the market, dupilumab has replaced most of the more traditional treatments for atopic dermatitis, said David Pariser, MD, senior physician at Pariser Dermatology Specialists.
Behavior Intervention Can Increase Physical Activity and Improve Asthma Control
November 25th 2020

Behavior Intervention Can Increase Physical Activity and Improve Asthma Control

Laura Joszt, MA
Patients with asthma can improve their disease control and sleep quality, while reducing depression and anxiety through a behavior change intervention aimed at increasing their physical activity.
Insurance Expansion Reduced Asthma Emergencies in New York City
November 17th 2020

Insurance Expansion Reduced Asthma Emergencies in New York City

Laura Joszt, MA
Expansion of insurance coverage due to the Affordable Care Act led to a reduction in the use of emergency services for patients with asthma in New York City.
eczema
November 15th 2020

Dupilumab Reduces Pain, Discomfort in Patients With Moderate to Severe Atopic Dermatitis

Laura Joszt, MA
Dupilumab, with or without topical corticosteroids, significantly reduced pain and discomfort in patients with moderate to severe atopic dermatitis.
Nicola Hanania, MD, MS, Baylor College of Medicine
November 11th 2020

Dr Nicola Hanania: Treatment of T2-High Asthma Is Constantly Evolving

Treatment targets include several interleukins, immunoglobulin E, and alarmins, pointed out Nicola Hanania, MD, MS, pulmonary critical care physician and director, Airway Clinical Research Center, Baylor College of Medicine, Houston.
asthma inhaler
November 8th 2020

Overuse of Reliever Inhalers Does Not Necessarily Mean Greater Health Care Utilization

Laura Joszt, MA
Overuse of reliever inhalers among adult patients with asthma is prevalent, but does not necessarily translate into higher all-cause health care utilization (HCU), according to a study published in Scientific Reports.
Anne Reihman, MD, University of Colorado
November 7th 2020

Dr Anne Reihman: Anti–IL-5 Therapies Can Be Life-Changing for Patients With Eosinophilic Asthma

Categorizing by eosinophilic/noneosinophilic subtype enables better targeted treatment, noted Anne Reihman, MD, third-year pulmonary and critical care fellow, University of Colorado, Division of Pulmonary Sciences and Critical Care Medicine.
Vitamin D supplementation
November 6th 2020

Vitamin D May Ease Symptoms of Severe Atopic Dermatitis in Children

Laura Joszt, MA
Vitamin D used as an adjuvant therapy in children with severe atopic dermatitis may improve clinical outcomes, according to a recent study.
J. Allen Meadows, MD
October 31st 2020

Dr J. Allen Meadows Discusses Adherence to Biologics for Asthma

Despite the price, adherence to biologics for asthma is usually good because of the effectiveness, said J. Allen Meadows, MD, president of the American College of Allergy, Asthma & Immunology.
Home health care
October 28th 2020

Weighing the Pros, Cons of At-Home Use of Biologics for Asthma

Laura Joszt, MA
When the first biologic to treat asthma was approved by the FDA in 2003, it needed to be administered subcutaneously in the physician’s office. Now, there are 3 options available for at-home use: mepolizumab, benralizumab, and dupilumab.
J. Allen Meadows, MD, president, American College of Allergy, Asthma & Immunology
October 22nd 2020

Dr J. Allen Meadows on Using Shared Decision-Making to Choose Among Biologics for Asthma

There are clear differences between the biologics approved to treat asthma, and finding the right one for a patient requires shared decision-making conversations, said J. Allen Meadows, MD.
Teen girl being comforted
October 19th 2020

Addressing the QOL Impact and Disease Burden on the Families of Adolescents With Atopic Dermatitis

Laura Joszt, MA
Atopic dermatitis (AD) has a negative impact on quality of life, and the burden of this disease in adolescents and their parents should be taken into account as part of the management of AD.
J. Allen Meadows, MD, American College of Allergy, Asthma & Immunology
October 14th 2020

Dr J. Allen Meadows on Making the Decision to Put a Patient With Asthma on a Biologic

Patients with severe asthma are good candidates for biologics, but choosing which biologic requires a shared decision-making conversation, said J. Allen Meadows, MD, president of the American College of Allergy, Asthma & Immunology.
child with asthma inhaler
October 14th 2020

Phase 3 Trial Finds Dupilumab Significantly Reduced Severe Asthma Attacks in Children

Laura Joszt, MA
Improvements in lung function occurred as early as 2 weeks after the first dose of treatment.
J. Allen Meadows, MD, president of the American College of Allergy, Asthma & Immunology
October 10th 2020

Dr J. Allen Meadows Outlines New Long-term Safety, Efficacy Data for Dupilumab in Asthma

New data on the long-term efficacy and safety of dupilumab are very reassuring to patients with asthma, explained J. Allen Meadows, MD, president of the American College of Allergy, Asthma & Immunology.
Dupilumab Improves Lung Function, Reduces Asthma Flares in Patients on High-Dose ICS
October 9th 2020

Dupilumab Improves Lung Function, Reduces Asthma Flares in Patients on High-Dose ICS

Laura Joszt, MA
Patients with type 2-high asthma who were being treated with high-dose inhaled corticosteroids (ICS) had reduced exacerbations and improved lung function when they were switched to dupilumab.
Dr Neal Jain Discusses Type 2 Inflammation in Asthma
September 30th 2020

Dr Neal Jain Discusses Type 2 Inflammation in Asthma

The majority of patients with asthma have type 2 inflammation, and the introduction of dupilumab has changed the treatment space for these patients, said Neal Jain, MD, FAAP, FAAAAI.
Dr Neal Jain on the Real-World Results of Dupilumab in Asthma
September 26th 2020

Dr Neal Jain on the Real-World Results of Dupilumab in Asthma

In the real world, dupilumab has been as effective as the results in clinical trials, and patients are seeing low exacerbation rates, emergency department visits, and hospitalizations, explained Neal Jain, MD, FAAP, FAAAAI.
Pediatric Asthma Health Care Utilization Following Onset of COVID-19 Pandemic
September 25th 2020

Pediatric Asthma Health Care Utilization Following Onset of COVID-19 Pandemic

Laura Joszt, MA
Following the onset of the coronavirus disease 2019 (COVID-19) pandemic, changes in pediatric asthma health care delivery patterns resulted in reduced hospital admissions and systemic steroid prescriptions in Philadelphia.
Anthem, Apple to Study How to Improve Asthma Self-management With Everyday Devices
September 22nd 2020

Anthem, Apple to Study How to Improve Asthma Self-management With Everyday Devices

AJMC Staff
The 2-year study will investigate how devices like the Apple Watch and the iPhone can help patients with asthma better manage their condition.
Dr Neal Jain Discusses the Use of Dupilumab in Oral Steroid–Dependent Asthma
September 19th 2020

Dr Neal Jain Discusses the Use of Dupilumab in Oral Steroid–Dependent Asthma

Patients who have oral corticosteroid–dependent asthma are recommended to use dupilumab, which reduces the use of oral steroids, explained Neal Jain, MD, FAAP, FAAAAI, of Arizona Allergy & Immunology Research.
Real-World Study Finds High Persistence With Dupilumab in Atopic Dermatitis
September 17th 2020

Real-World Study Finds High Persistence With Dupilumab in Atopic Dermatitis

Laura Joszt, MA
The high rate of persistence found in the real-world study indicates dupilumab was well tolerated and patients were satisfied with its effectiveness.
Real-World Study: Dupilumab for Atopic Dermatitis More Effective Than Clinical Trial Results
September 12th 2020

Real-World Study: Dupilumab for Atopic Dermatitis More Effective Than Clinical Trial Results

Laura Joszt, MA
The broadest real-life study of dupilumab in atopic dermatitis (AD) found significant improvements in adults with moderate to severe AD that were even greater than the results reported in clinical trials.
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