Jared Kaltwasser

The fully humanized monoclonal antibody led to results among patients with generalized myasthenia gravis (MG) similar to that of efgartigimod, the authors said.

The patient had both classical Hodgkin lymphoma and diffuse large B-cell lymphoma.

Investigators say the findings could lead to new therapeutic targets.

The findings add complexity to questions about the long-term impact of acute lymphoblastic leukemia (ALL) therapy.

Patients with chronic lymphocytic leukemia (CLL) who discontinued ibrutinib had higher rates of adverse events compared with those who continued the therapy, the authors found.

Other viral infections, including Epstein-Barr virus and hepatitis C, have already been linked with primary hepatic lymphoma, the authors said.

Investigators say a better understanding of risk factors and categories can help personalize care for patients living with myelodysplastic syndrome (MDS).

The retrospective study found patients on Bruton’s tyrosine kinase inhibitors are similar to the general population in the sense that it usually takes at least 2 anti-hypertensive drugs to control blood pressure.

These findings suggest complement protein levels may be an important biomarker for type 1 diabetes.

Ten of 13 patients with leukemic pulmonary infiltrates (LPI) and chronic lymphocytic leukemia (CLL) had single or multiple nodular/mass-like opacities, authors found.

The data also show how the economic burden of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is increasing.

Investigators say adolescents had difficulty adhering to the workbook-based program, but the authors said changes—and perhaps a digital format—could improve the program’s performance.

A review of recent research into myelodysplastic syndromes (MDS) shows a range of potential therapeutic targets.

Investigators found patients receiving chemotherapy had a greater risk of a secondary primary malignancy (SPM) compared with those treated with targeted therapies or those whose chronic lymphocytic leukemia (CLL) was left untreated.

About half of patients receiving the procedure did not need medication to control their blood pressure after 5 years.

The authors say their 3D model improves on results using traditional 2-dimensional approaches.

Most of the research suggests combination therapies might be the best option for many patients who have acute myeloid leukemia (AML).

Among the 10 patients in the retrospective analysis, the median overall survival after allogeneic hematopoietic stem cell transplantation (allo-HSCT) for relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL) was 21 months.

The study may help explain why some patients are more prone to relapse following a complete response to induction therapy, as indicated by measurable residual disease (MRD) status and 2017 European LeukemiaNet (ELN) criteria.

The authors suggest the phenomenon of 2 mutationally distinct diffuse large B-cell lymphomas (DLBCLs) might be more common than currently understood.

Investigators say attempts to overcome mutational resistance to Bruton’s tyrosine kinase (BTK) inhibitors have had mixed results among patients who have chronic lymphocytic leukemia (CLL).

New methods of classifying patients could pave the way for more personalized treatment approaches, a new report states.

A new report compared the blood immune repertoires of patients with chronic lymphocytic leukemia (CLL) who received chemoimmunotherapy and those who received ibrutinib.

Although ibrutinib adds to the cost of treatment, its benefits over the long term justify the cost, investigators found.

Investigators said analysis of multiple tissues from the same patients suggests tumor evolution in high-grade serous ovarian cancer (HGSC) was not through somatic mutations.

Investigators say computer algorithms can be used to assess physical and vocal signs of myasthenia gravis (MG).

Full team coverage from the European Hematology Association 2023 Hybrid Congress, which took place June 8-11 in Frankfurt, Germany.

The study also found people with vitamin D deficiency had a lower mortality rate from Clostridioides difficile infection (CDI).

The study was designed to help scientists better understand how to prevent in-hospital transmission of Clostridioides difficile.

Committees have worked for the past 4 years to develop uniform definitions of immunotherapy resistance, but they are not yet universally used.