Jared is a freelance writer for The American Journal of Managed Care® (AJMC®), and previously worked as a senior editor for HCPLive® at MJH Life Sciences®.
He has an MA from University of Sioux Falls. You can connect with Jared on LinkedIn.
Inflammation Could Prove Meaningful Target in Myasthenia Gravis
The article suggests the inflammatory components of myasthenia gravis have been underexplored in the effort to develop new therapies.
Study Identifies FGFR3 as Biomarker for Superior Outcomes in NSCLC
Positive expression levels of the biomarker were more common in adenocarcinoma than in squamous cell carcinoma, among patients who had non–small cell lung cancer (NSCLC).
Similar Survival Rates Seen Among Black African Americans With PMF, Other Groups
The study also found, however, that transplant outcomes appear to be worse for Black African American patients who have primary myelofibrosis (PMF), although the study utilized a small sample size.
Spleen Response Closely Linked With Survival in MF While on Ruxolitinib
Patients with myelofibrosis (MF) who achieved a spleen response while taking ruxolitinib and lost it had survival outcomes similar to patients who did not respond, according to results from a real-world study.
Live Cell-Based Assays May Find Antibodies in Some Seronegative MG Cases
A different type of test may improve diagnosis for some patients with myasthenia gravis (MG).
Immune Signature Could Help Tailor Treatment Choices in NSCLC
The authors identified 2 subgroups with non–small cell lung cancer (NSCLC) who had different responses to common cancer therapies.
Ruxolitinib Well Tolerated in Untreated Patients With Polycythemia Vera
The results of the futility analysis also suggest the therapy leads to significant clinical benefits.
Real-World Data Show SCLC Outcomes Remain Grim
The authors say newer treatment options for small cell lung cancer (SCLC) may lead to improvement in this area of high unmet need.
Two Cases Demonstrate Potential Renal Complications of MDS/MPN
Evidence suggests as many as 29% of people with myeloproliferative neoplasms (MPN) or myelodysplastic syndrome (MDS)/MPN have chronic kidney disease.
Links Between Ancestry, Immunogenomic Landscape Investigated in Prostate Cancer
The study found 143 loci where somatic copy numbers were varied based on genetic ancestry.
Surgical Quality Metric Adherence Substantially Improves Outcomes in Early NSCLC
Overall survival and recurrence-free survival showed substantial improvement when physicians more closely followed quality recommendations for non–small cell lung cancer (NSCLC).
Case Shows Difficulty of Diagnosing Myasthenia Gravis Following COVID-19
The patient, an 83-year-old man, experienced onset of myasthenia gravis after a severe SARS-CoV-2 infection.
Many Rural Hospitals Lacked Oncology Care, Telehealth, or Both Before the Pandemic
The report helps clarify the urban/rural divide in cancer outcomes and the digital divide in telehealth access.
New Prostate Cancer Screening Method Could Reduce Risk of Overdiagnosis
The method had high rates of sensitivity and specificity, although its sensitivity was somewhat lower in cases of localized prostate cancer.
Randomized Prospective Trial Suggests AI Improves Lung Cancer Screening
Artificial intelligence (AI) improved detection of actionable lung nodules without leading to higher rates of false positives, the study found.
Myasthenia Gravis Likely Leads to Significant Impact on QOL
Even patients with the mildest symptoms of myasthenia gravis said they experienced negative quality-of-life (QOL) effects from the disease.
Case Highlights EoE With Dysphagia Despite No Asthma, Atopic Disease History
Such cases of eosinophilic esophagitis (EoE) are rare, but they can be treated with the typical therapies for EoE.
Common PsA Symptoms Negatively Impact Quality of Life
A study attempted to see how symptoms affect quality of life after adjusting for confounding factors.
Inflation Reduction Act Could Cut Medicare Drug Spending by 5%, Study Suggests
The bill could have saved CMS about $26.5 billion had it been in place from 2018-2020, the study showed.
Prevalence of Mental Health Comorbidities in Psoriasis Probed in New Study
The exact reasons for the links are not yet clear, although some evidence suggests inflammation plays a role.
Diabetes Prevention App Users More Likely to Be Female, Obese vs General Population
This new study examined uptake and use of a digital tool meant to aid in diabetes prevention.
Lower CTLA4 Levels May Indicate Risk of MG in Patients With Thymoma
The findings from among patients with myasthenia gravis (MG) could point the way to a potential new drug target, the authors said.
Veterans Health Stakeholders Identify Priorities to Ensure Health Equity in Telehealth
First steps include assembling equity data and reaching out to veterans’ advocacy groups.
CRISPR Knockout Identifies New Biomarkers for PARP Inhibitor Resistance in Prostate Cancer
The report also suggests that ataxia telangiectasia and Rad3-related protein inhibition could be a valuable tool to overcome resistance.
Telehealth Likely as Effective as In-Person Care for MDD
Patients were also more likely to stay in treatment longer when their care was delivered virtually, a new survey has found.
Route Does Not Impact Diagnostic Accuracy of Micro-Ultrasound Targeted Prostate Biopsies, Study Finds
The report suggests that high-resolution micro-ultrasound could help identify clinically significant lesions that would be missed with conventional MRI.
PD-L1 Scoring in NSCLC Varies Significantly
This new study has found different labs followed similar practices, but the way they scored patients varied significantly.
Low-risk MDS Management May Change as New Technology, Therapies Emerge
A new review article shows how technologies like next-generation sequencing might help clinicians tailor care for myelodysplastic syndromes (MDS).
Potential Molecular Mechanisms That Increase COVID-19 Risk in Lung Cancer Highlighted
This experimental research suggests the expression levels of certain genes might help explain why people with lung cancer often have more severe cases of COVID-19.
Potential Link Found Between Spikes in Air Pollution, Outpatient Psoriasis Visits
Female patients and people younger than 18 years were particularly sensitive to pollution levels, this study found.