Hematology

Optimizing the Use of MRD Testing in Multiple Myeloma

March 18th 2021, 7:30pm

Article

Minimal residual disease (MRD) is being used more frequently in clinical trials and to identify the best treatment course for patients, but unknowns remain about the optimal use of MRD testing.

Lenacapavir Against HIV Demonstrates Ongoing Potential

March 16th 2021, 5:37pm

Article

The safety and effectiveness of the long-acting agent is backed by data from trials of the drug among treatment-experienced individuals living with HIV-1 whose viral load is on the rise due to other regimens failing. Investigation continues among these patients, as well as treatment-naive patients.

Highlighting Resiliency During Multiple Myeloma Awareness Month 2021

March 13th 2021, 6:30pm

Article

Multiple myeloma is not easily diagnosed, and its early symptoms may be confused for another condition.

CAR T Therapy Induces Response in Majority of Patients With Relapsed Multiple Myeloma

March 10th 2021, 1:29pm

Article

Idecabtagene vicleucel induced progression-free survival up to 20 months and a complete response in one-third of patients with multiple myeloma who had relapsed multiple times and had received at least 3 previous lines of treatment.

Report Describes Case of Improved Outcome in MM With Personalized Medicine

March 6th 2021, 7:00pm

Article

Researchers describe the case of an older patient who underwent myeloma drug sensitivity testing as part of an effort to identify the therapies most likely to produce a response in this difficult-to-treat population.

Marrow Lymphocyte Patterns After ASCT May Have Prognostic Value in MM

March 5th 2021, 2:30pm

Article

Patients with multiple myeloma (MM) often relapse over time despite initially achieving a complete response without minimal residual disease following induction treatment, leaving questions about changes in the immune system and the prognosis of the disease.

Trial of Anti-BCMA ide-cel for RRMM Leads to Undetectable Disease in 33% of Patients

February 27th 2021, 8:30pm

Article

More than 2 years after treatment, some of the patients with relapsed/refractory multiple myeloma have yet to see a relapse. An FDA decision on the therapy is expected within a month.

FDA Clears Peptide-Drug Conjugate for RRMM

February 27th 2021, 4:15am

Article

The peptide-drug conjugate rapidly delivers an alkylating payload into tumor cells.

Combination Treatment Maintains Quality of Life in Relapsed/Refractory MM

February 20th 2021, 11:00pm

Article

Health-related quality of life was maintained when treating relapsed/refractory multiple myeloma (RRMM) with daratumumab in combination with bortezomib and dexamethasone.

Sustained MRD Negativity Predictive of Long-term Outcomes in RRMM

February 16th 2021, 5:42pm

Article

Sustained minimal residual disease (MRD) negativity may predict long-term outcomes in relapsed/refractory multiple myeloma (RRMM), and daratumumab-based combinations show higher rates of sustained MRD negativity compared with the standard of care.