Myasthenia Gravis

Latest News

Myasthenia Gravis | Image Credit: Bediha Duru Öksüz-stock.adobe.com
Zilucoplan Shows Rapid, Durable, Steroid-Sparing Benefits in gMG

June 12th 2025

Zilucoplan (Zilbrysq; UCB) is a once-daily subcutaneous C5 complement inhibitor that has demonstrated long-term treatment benefits in patients who have acetylcholine receptor antibody–positive generalized myasthenia gravis (gMG).

osteoporosis | Image Credit: reineg-stock.adob.ecom
Combining Bone Health, Function Scores Refines MG Fracture Prediction

May 30th 2025

Light sensitivity is a potential symptom of myasthenia gravis that has historically been under-researched, according to study authors. | Image credit: lexiconimages - stock.adobe.com
Light Sensitivity Linked With Lower Quality of Life in Myasthenia Gravis

May 23rd 2025

Rystiggo | Image Credit: © UCB
Rozanolixizumab for gMG Approved in Japan for Self-Administration

May 15th 2025

FDA approved. | Image Credit: Pawel - stock.adobe.com
FDA Approves Nipocalimab for Generalized Myasthenia Gravis

April 30th 2025

More News

Judith Thompson, PharmD, MPH | Image Credit: UCB Pharma
November 3rd 2023

SDOH Lead to Greater Suboptimal Treatment Response in Myasthenia Gravis

Marco Meglio
A retrospective study presented at the 2023 American Association of Neuromuscular and Electrodiagnotsic Medicine meeting revealed that social determinants of health (SDOH) are linked to poorer treatment outcomes in patients who have myasthenia gravis, emphasizing the need for identifying and supporting at-risk individuals.
Medical team having a meeting, with doctors in white lab coats and surgical scrubs seated at a table discussing patients, working online using computers in medical industry | Image Credit: mrmohock - stock.adobe.com
October 31st 2023

MG Symptoms PRO Potential New Tool to Evaluate MG Symptom, Disease Severity

Maggie L. Shaw
Investigators evaluated the utility of the MG Symptoms Patient-Reported Outcome (PRO) within the armamentarium of instruments that currently evaluate myasthenia gravis (MG) severity.
Myasthenia gravis diagnosis | Image Credit: Andrii - stock.adobe.com
October 27th 2023

Pembrolizumab-Induced Myasthenia Gravis Case Points to Need for Treatment Standardization

Maggie L. Shaw
This case report details an incident of pembrolizumab-induced myasthenia gravis in an elderly male patient being treated for urothelial cell bladder cancer.
MJames F. Howard, D, FAAN | Image Credit: University of North Carolina at Chapel Hill School of Medicine
October 21st 2023

FDA Approves Complement C5 Inhibitor Zilucoplan for Myasthenia Gravis

Marco Meglio
With the approval, zilucoplan becomes the first once-daily subcutaneous complement C5 inhibitor available for adults with generalized myasthenia gravis.
myasthenia gravis word or concept represented by black and white letter cubes on a grey horizon background stretching to infinity | Image Credit: lexiconimages - stock.adobe.com
October 18th 2023

Older Age, Male Sex Identified as Potential Risk Factors for MG Following COVID-19 Vaccination

Maggie L. Shaw
A new analysis has determined potential risk factors for developing myasthenia gravis following COVID-19 vaccination, with symptoms likely to appear within 2 weeks of receipt of a COVID-19 vaccine.
Health Insurance Concept | Image credit: A stockphoto - stock.adobe.com
October 10th 2023

gMG Imposes an Enormous Economic Burden on Patients

Maggie L. Shaw
Qualitative interviews were conducted and a web-based quantitative survey was administered to have a clearer understanding of the economic impact of social determinants of health on patients living with generalized myasthenia gravis (gMG).
Myasthenia gravis. The text label of the medical diagnosis. Treatment with medications and procedures | Image Credit: Николай Зотов
September 29th 2023

Subanalysis of ADAPT Reveals Consistent Efficacy With Efgartigimod Among All Genders

Isabella Ciccone, MPH
Patients with generalized myasthenia gravis treated with efgartigimod consistently exceeded treatment compared with placebo regardless of gender in age, disease duration, body mass index, and thymectomy.
Medicine doctor hold icon health and electronic medical record on interface. Digital healthcare and network connection on hologram virtual screen, insurance. medical technology and network concept | Image Credit: ipopba - stock.adobe.com.
September 25th 2023

ICI Treatment Necessitates Close Monitoring of Potential Myasthenia Gravis

Maggie L. Shaw
Overactivation of the immune system is a potential serious adverse event (AE) following immune checkpoint inhibition (ICI) treatment for any of several cancers in the first and second line; among these AEs is myasthenia gravis.
Myasthenia Gravis. Myasthenia Gravis disease blood test inmedical laboratory | Image Credit: luchschenF
September 20th 2023

Myasthenia Gravis Treatment Landscape Rapidly Evolving

Maggie L. Shaw
Approximately 70 to 300 million individuals worldwide are living with myasthenia gravis, an antibody-mediated autoimmune disorder that adversely affects neuromuscular junction function.
Medical concept meaning MYASTHENIA GRAVIS with inscription on the sheet | Image Credit: Yurii Kibalnik - stock.adobe.com
September 15th 2023

PASS “Yes” Status in MG Potentially Achievable 2 Years After Diagnosis

Maggie L. Shaw
Patient acceptable symptom state (PASS) may be a reliable indicator of long-term outcomes among patients who have myasthenia gravis (MG).
John Vissing, MD, DMSci, Copenhagen Neuromuscular Center, University of Copenhagen,
September 9th 2023

Generalized Myasthenia Gravis Symptom Severity Reduced Through Ravulizumab Treatment

Isabella Ciccone, MPH
The highest proportions of patients with severe ocular impairment at baseline showed greater improvements in symptom severity on ravulizumab in comparison with placebo after 26 weeks.
myasthenia gravis word or concept represented by black and white letter cubes on a grey horizon background stretching to infinity: © lexiconimages - stock.adobe.com
September 6th 2023

Digital Phenotyping Potential Clinical Tool in Myasthenia Gravis

Maggie L. Shaw
The investigation evaluated if symptom signatures of myasthenia gravis exacerbations could be evaluated using real-world data gathered via a smartphone-based research platform.
Myasthenia gravis is shown on the conceptual medical photo: © Andrii - stock.adobe.com
August 30th 2023

Psychological Health Important Consideration for Myasthenia Gravis Space

Maggie L. Shaw
With this study, investigators hoped to describe personality traits among individuals who have the autoimmune, neuromuscular disease.
Concept of Myasthenia Gravis write on sticky notes with stethoscope isolated on Wooden Table: © syahrir - stock.adobe.com
August 24th 2023

Computer-Aided MG Assessment Could Facilitate Broader Use of Telehealth

Jared Kaltwasser
Investigators say computer algorithms can be used to assess physical and vocal signs of myasthenia gravis (MG).
Muscle Specific Kinase or MuSK protein test. Myasthenia gravis. Autoimmune disease: © Saiful52 - stock.adobe.com
August 16th 2023

Cell-Based Assay Outperforms Others for Antibody Detection in Myasthenia Gravis

Maggie L. Shaw
This study compared autoantigen detection of acetylcholine receptor and muscle-specific kinase, among 3 assays used in suspected cases of myasthenia gravis.
Book about Myasthenia gravis and medication, injection, syringe and pills:Black book © mdaros - stock.adobe.com
August 9th 2023

Myasthenia Gravis Prevalence Increasing, Linked to Hepatitis B Virus in Taiwan

Maggie L. Shaw
Study authors used data from the Taiwan National Healthcare Insurance Research database and Death Registry for their population-based retrospective cohort study.
Concept of Myasthenia Gravis write on sticky notes isolated on Wooden Table: © syahrir - stock.adobe.com
August 5th 2023

Zilucoplan Demonstrates Consistent Efficacy in Phase 3 RAISE Study of Generalized Myasthenia Gravis

Isabella Ciccone, MPH
Nearly half of patients treated with zilucoplan were considered responders on Myasthenia Gravis Activities of Daily Living (MG-ADL) at the first week, suggesting a rapid onset of efficacy.
Tablet with word myasthenia and stethoscope: © Vitalii Vodolazskyi - stock.adobe.com
August 2nd 2023

Case Investigated of Patient With Possible COVID-19–Induced Myasthenia Gravis

Maggie L. Shaw
Investigators conducted a case study of a patient who presented with COVID-19–induced seronegative myasthenia gravis, seeking more information on neurological manifestations of the respiratory disease.
Myasthenia gravis. The text label of the medical diagnosis. Treatment with medications and procedures: © Николай Зотов
July 27th 2023

Research Finds Efficacy of LPE Similar to PE in Patients With MG

Gianna Melillo
Lymphoplasmapheresis (LPE) was also completed with fewer replacements compared with plasma exchange (PE) for myasthenia gravis (MG).
Toxoplasmosis (infectious disease) diagnosis medical concept on tablet screen with stethoscope: © ibreakstock - stock.adobe.com
July 22nd 2023

Rare Case of CNS Toxoplasmosis Seen in Patient With Myasthenia Gravis

Gianna Melillo
The patient was found to have Toxoplasma gondii, a parasitic infection, and died 5 months after his initial diagnosis.
Myasthenia gravis is shown on the conceptual medical photo By Andrii - stock.adobe.com
July 20th 2023

Real-World Data Highlight Benefits of Thymectomy in Patients With NTMG

Gianna Melillo
However, few patients with nonthymomatous myasthenia gravis (NTMG) undergo this procedure, results suggest.
Myasthenia Gravis. Myasthenia Gravis disease blood test in doctor hand: © luchschenF - stock.adobe.com
July 13th 2023

Uncontrolled Disease Common in Patients Grappling With Myasthenia Gravis

Gwen Mergian
A real-world study of 5 European countries shows frequent misdiagnoses/delays in diagnosis, acute hospitalizations, and quality-of-life impairments.
myasthenia gravis word or concept represented by black and white letter cubes on a grey horizon background stretching to infinity: © lexiconimages - stock.adobe.com
July 8th 2023

Endoscopic Surgery “Unmasks” Undiagnosed Myasthenia Gravis

Jared Kaltwasser
The patient in this case experienced significant muscle weakness after emerging from anesthesia.
SDOH social determinants of health nonmedical factors that influence health: © bakhtiarzein - stock.adobe.com
July 7th 2023

Survey Assesses Impact of SDOH on Patients With Generalized Myasthenia Gravis

Gianna Melillo
The rare autoimmune disorder generalized myasthenia gravis can cause muscle weakness in the limbs and face.
FDA approved red stamp on white background
June 27th 2023

FDA Approves Rozanolixizumab-noli for Generalized Myasthenia Gravis

Laura Joszt, MA
The treatment is the first approved by the FDA to treat the 2 most common subtypes of generalized myasthenia gravis.
patient holding hands
June 9th 2023

Innovative Therapies Show Promise Improving MG Symptoms

Jared Kaltwasser
Both complement inhibitors and neonatal Fc receptor blockers led to improvements in symptoms, according to a meta-analysis.
image of patient getting care
June 7th 2023

New Symptom Cluster Scale for MG Aims to Better Guide Patient Care

Jared Kaltwasser
The scale is meant to better quantify how clusters of symptoms impact patients’ quality of life.
James Howard, MD
June 2nd 2023

Unmet Needs in Myasthenia Gravis Are Numerous, Says Dr James Howard

Allison Inserro
Unmet needs include both improved myasthenia gravis treatments as well as a way to monitor progression of the disease, said James F. Howard, Jr, MD, professor of neurology at the University of North Carolina at Chapel Hill.
James Howard, MD
May 26th 2023

Dr James Howard on the Complications of Standard Myasthenia Gravis Therapies

Allison Inserro
Current myasthenia gravis therapies can exacerbate comorbidities or create other complications, said James F. Howard Jr, MD, professor of neurology at the University of North Carolina at Chapel Hill.
Stressed mature business woman looking worried, tired and overwhelmed while working with laptop on a desk in the office at home: © nenetus - stock.adobe.com
May 23rd 2023

MG Has Significant Impact on Patients’ Work, Survey Shows

Jared Kaltwasser
The majority of respondents living with generalized myasthenia gravis (MG) were not working, the results showed.
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