Heart Failure

The AJMC® Heart Failure compendium is a comprehensive resource for clinical news and expert insights for the chronic condition in which the heart doesn't pump enough blood due to damaged heart muscle.

Latest News
October 11th 2024

Remote Monitoring Program Cuts Heart Failure Readmissions in Half

October 2nd 2024

Optimizing GDMT Could Prevent Over 1 Million HFrEF Deaths Annually

September 26th 2024

Adherence to 2021 ESC Heart Failure Guidelines Differed Across Practices

September 25th 2024

Study Reveals High Variability in Hospital GDMT Scores, Outcomes, Costs

September 25th 2024

Sacubitril/Valsartan, Enalapril Show Comparable Efficacy in Pediatric Heart Failure

Heart Failure Clinical and Economic Burden

An in-depth discussion on the clinical and economic burden of treatment for patients with heart failure, with special consideration to progressive disease.

John McMurray screenshot
Video Interviews
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September 30th 2024

Advancing the Field of Valve Interventions for Mitral and Tricuspid Regurgitation

August 26th 2024

Dr Martha Gulati Previews ESC 2024: Obesity, Heart Failure, and the Ongoing Debate on HRT

June 15th 2024

Dr Kathryn Lindley Addresses Barriers to Women’s Heart Disease Diagnosis

April 23rd 2024

Dr Sophia Humphreys Explains Health Equity in Metabolic Health Care

April 20th 2024

Dr Ryan Stice Shares Strategy on Expanding Access to Care With Virtual Population Health Teams

April 19th 2024

Dr Ronesh Sinha: Changing Cardiometabolic Health With Continuous Glucose Monitoring

October 13th 2023

Dr Javed Butler: How STEP-HFpEF Findings on Semaglutide Translate to Clinical Practice

October 3rd 2023

Dr Jennifer Sturgill Addresses IRA Drug Price Negotiations and the Current Drug Shortage

September 28th 2023

How Will DICTATE-AHF Findings Affect Clinical Practice? Dr Zachary Cox Explains

September 14th 2023

Dr Zachary Cox: Early Dapagliflozin Modestly Improves Diuresis, Decongestion for Patients With ADHF

Podcasts
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August 29th 2023

The Importance of Examining and Preventing Atrial Fibrillation

February 7th 2023

Intermountain Healthcare and Story Health Partner to Optimize Rural Heart Failure Care

December 17th 2021

Investigating the Spreading Uptake of Sacubitril/Valsartan Across the US

September 28th 2021

Reviewing Race and Kidney Disease in the NKF-ASN Task Force Report

November 24th 2019

Podcast: This Week in Managed Care—Heart Disease Treatment and Other Health News

September 22nd 2019

Podcast: This Week in Managed Care—HIV Screening Rates and Other Health News

September 8th 2019

Podcast: This Week in Managed Care—Opioid Prescribing Trends, and Other Health News

August 25th 2019

Podcast: This Week in Managed Care—BRCA Testing Recommendation and Other Health News

May 12th 2019

Podcast: This Week in Managed Care—Drug Prices on Television and Other Health News

Continuing Medical Education
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October 13th 2024

Advances and Best Practices for Managed Care Pharmacists in the Treatment of Heart Failure with Preserved Ejection Fraction

1.0 Credits / Cardiology
October 13th 2024

Exploring Transthyretin-Mediated Amyloidosis and Its Phenotypes: A Comprehensive Approach to Patient Treatment

1.5 Credits / Cardiology, Neurology, Rare Diseases
October 13th 2024

The Economics of Transthyretin-Mediated Amyloidosis: Balancing Equity and Access in Resource Allocation

1 Credit / Cardiology, Neurology

More News

Wegovy injections and packaging | Image credit: Ole – stock.adobe.com
August 24th 2024

Patients With Heart Failure May Benefit From Weight Loss Drug

Hayden E. Klein
New research indicates that the heart benefits of semaglutide can extend to those with heart failure.
Hospital building | Image credit: Spiroview Inc. – stock.adobe.com
August 23rd 2024

Postdischarge Mortality Remains Unchanged Despite Advances in Heart Failure Care

Hayden E. Klein
Heart failure mortality rates after hospital discharge have seen little improvement since 2010 among Medicare beneficiaries, with real-world outcomes falling short of clinical trial expectations.
Electrocardiogram in hospital surgery operating emergency room | Image credit: totojang1977 – stock.adobe.com
August 15th 2024

Surgery Improves Outcomes for Patients With Atrial Functional Mitral Regurgitation

Hayden E. Klein
A new study found that older patients with atrial functional mitral regurgitation who underwent mitral valve surgery had significantly better outcomes than those who received medical management alone, including lower rates of heart failure hospitalization and death.
Finerenone, a nonsteroidal, selective mineralocorticoid receptor antagonist (MRA), is the first MRA to reach a primary cardiovascular end point in a phase 3 study in heart failure with mildly reduced or preserved injection fraction. | Image credit: Robert-stock.adobe.com
August 9th 2024

Finerenone Reduces Cardiovascular Death, HF Events in FINEARTS-HF Trial

Rose McNulty
The investigational therapy for heart failure (HF) with mildly reduced or preserved injection fraction met its primary end point in the phase 3 trial, Bayer announced.
FDA | Image credit: Araki Illustrations – stock.adobe.com
July 18th 2024

FDA Grants Breakthrough Device Designation to ContraBand System to Treat HFrEF

Hayden E. Klein
The catheter-delivered implant uses the right ventricle to support the left, improving left ventricle ejection fraction and helping restore the heart’s normal shape.
US and Japan flags | Image credit: Oleksii – stock.adobe.com
July 18th 2024

Key Differences in Heart Failure Management, Outcomes Between US and Japan

Hayden E. Klein
A new study revealed longer heart failure hospital stays, better 30-day follow-up, and lower mortality rates in Japan compared with the US.
Salt and salt shaker | Image credit: Melica – stock.adobe.com
July 15th 2024

Lowering Sodium Intake Reduces AF Risk, but Does Not Improve Heart Failure Outcomes

Hayden E. Klein
New studies say restricting salt intake can reduce the risk of atrial fibrillation (AF) in certain patients, but cannot reduce the risks of morbidity and death in patients with heart failure.
Kathryn Lindley, MD, FACC – Vanderbilt University Medical Center
July 5th 2024

How Vanderbilt's Women's Heart Center Is Bridging the Gender Gap in Heart Health

Hayden E. Klein
Kathryn Lindley, MD, FACC, Vanderbilt University Medical Center, emphasizes the importance of bringing heart health care to patients and meeting them where they are.
Elevated lipoprotein(a) and oxidized phospholipids were found to be independent risk factors for early-stage heart failure progression. | Image credit: Robert - stock.adobe.com
June 28th 2024

Study Finds Lp(a), Oxidized Phospholipids Predict Heart Failure Progression

Patrick Campbell
New research reveals that elevated lipoprotein(a) and oxidized phospholipids are independent risk factors for early-stage heart failure progression.
Blood vessel | Image credit: Dr_Microbe – stock.adobe.com
June 17th 2024

STRONG-HF Data Suggest Bio-ADM Enhances Heart Failure Prognostic Value

Hayden E. Klein
Patients with the highest biologically active adrenomedullin (bio-ADM) levels at baseline were 114% more likely to die from any cause or be readmitted to the hospital for heart failure within 6 months compared with patients with the lowest levels.
Older woman smelling flowers | Image credit: Halfpoint – stock.adobe.com
June 14th 2024

Loss of Smell May Predict Heart Failure Risk

Hayden E. Klein
Adults aged 70 and older were significantly more likely to develop congestive heart failure if they also experienced olfactory impairment.
Heart failure | Image credit: lovelyday12 – stock.adobe.com
May 29th 2024

Patients With Diabetes and Heart Failure May Face Worse Outcomes, Increased HFpEF Risk

Hayden E. Klein
According to new research from Jordan, patients with both heart failure (HF) and diabetes had a higher prevalence of HF with preserved ejection fraction (HFpEF), elevated cholesterol, low-density lipoprotein, and impaired kidney function.
Aortic valve surgery | Image credit: Damian – stock.adobe.com
May 22nd 2024

ViV-TAVR Leads to Fewer Complications, but Increases Later Heart Failure Hospitalizations and Mortality

Hayden E. Klein
From 2015 to 2020, the number of patients opting for valve-in-valve transcatheter aortic valve replacement (ViV-TAVR) over redo surgical aortic valve replacement (SAVR) rose significantly, from 35.3% to 62.5%.
Woman walking on treadmill with trainer standing by | Image credit: ID_Anuphon – stock.adobe.com
May 20th 2024

Semaglutide Linked to Improved Exercise Capacity, Weight Loss in Patients With HFpEF and Obesity

Hayden E. Klein
Patients taking semaglutide for a year saw significant improvements in exercise capacity and lost 2.9% more body weight compared with patients taking placebo.
Kathryn Lindley, MD, FACC – Vanderbilt University Medical Center
May 15th 2024

What Women Should Know About Their Heart Health, According to Dr Kathryn Lindley

Hayden E. Klein
Kathryn Lindley, MD, FACC, Vanderbilt University Medical Center, shares what women can do to prioritize their heart health during National Women's Health Week and every week.
Chambers of the heart | Image credit: melazerg – stock.adobe.com
April 17th 2024

Heart Study Shows Atrial Shunting Shrinks Left Side, Expands Right

Hayden E. Klein
Patients who responded positively to shunt treatment experienced more beneficial changes in their heart's structure and function compared with nonresponders.
AJMC
April 4th 2024

Impact of Care Coordination on 30-Day Readmission, Mortality, and Costs for Heart Failure

Guann-Ming Chang, MD, MS Yu-Chi Tung, PhD
Enhancing coordination of care has the potential to increase the value of heart failure care.
Stethoscope on smartphone | Image credit: AndSus – stock.adobe.com
April 2nd 2024

FDA Approves AI Stethoscope for Earlier Heart Failure Detection

Hayden E. Klein
Eko Health's artificial intelligence (AI) tool can detect low ejection fraction in seconds via an Eko stethoscope, bringing earlier heart failure detection to routine checkups.
COVID-19 vaccine | Image credit: Leigh Prather – stock.adobe.com
March 25th 2024

Study Says COVID-19 Vaccines Can Reduce Risk of Heart Failure, Blood Clots Following Infection

Hayden E. Klein
COVID-19 vaccination was associated with reduced risks of acute and post–acute COVID-19 heart failure, venous thromboembolism, and arterial thrombosis/thromboembolism.
Doctor using stethoscope on patient's heart | Image credit: joyfotoliakid – stock.adobe.com
March 23rd 2024

Midodrine Use Linked to Decrease in HFrEF-Related ED Visits

Hayden E. Klein
However, researchers saw higher risks of respiratory failure, longer stays in the intensive care unit, increased hospitalizations, and elevated mortality rates in patients with heart failure with reduced ejection fraction (HFrEF) taking the antihypotensive medication.
Cash money stethoscope cost | Image credit: adragan – stock.adobe.com
March 21st 2024

Perceived Economic Burden Linked to HF Mortality Risk, Study Says

Hayden E. Klein
Increased perceived economic burden (PEB) was associated with an increased risk of mortality and poorer health status among patients with acute decompensated heart failure (HF).
Doctor visit during pregnancy | Image credit: pressmaster – stock.adobe.com
March 12th 2024

Severe Prenatal Grief May Increase Child’s Heart Failure Risk

Hayden E. Klein
Research found that maternal loss of a partner or older child, as well as the loss of a close relative due to unnatural causes in the year before or during pregnancy, were linked to a heightened risk of heart failure in offspring.
Atorvastatin | Image credit: Soni's – stock.adobe.com
February 23rd 2024

30-Day Atorvastatin Improved Brachial Artery FMD in Patients With HFpEF, but More Research Is Needed

Hayden E. Klein
This study was the first of its kind to explore how taking statin medication affects blood vessel function and exercise response in patients with heart failure with preserved ejection fraction (HFpEF), although the cohort only included 16 patients.
BMI scale | Image credit: Olivier Le Moal – stock.adobe.com
February 23rd 2024

There Is No Interaction Between BMI and SGLT2 Inhibitor Efficacy in HF, Review Finds

Hayden E. Klein
Among patients with heart failure (HF), those taking dapaglifozin or empaglifozin had a 30% odds reduction in HF hospitalization, 14% odds reduction in cardiovascular mortality, and a 10% odds reduction in all-cause mortality compared with patients taking placebo.
Women hula hooping | Image credit: Rawpixel.com – stock.adobe.com
February 21st 2024

More Physical Activity Linked to Reduced HF Risk in Older Women

Hayden E. Klein
Increased daily step count was linked to reduced risks of overall heart failure (HF) and HF with preserved or reduced ejection fraction.
Pacemaker | Image credit: Birgit Reitz-Hofmann – stock.adobe.com
February 5th 2024

Permanent Pacemaker Implantation Frequently Follows Tricuspid Valve Surgery, Study Finds

Hayden E. Klein
Among Medicare beneficiaries, implantation was especially frequent for female patients and those undergoing tricuspid valve replacement with or without concomitant left-sided heart surgeries.
Heart | Image credit: abhijith3747 - stock.adobe.com
January 28th 2024

Low Muscle Mass, Hypoalbuminemia Increase Mortality Risk in ADHF

Rose McNulty
Patients admitted to the hospital with acute decompensated heart failure (ADHF) who also had low muscle mass and hypoalbuminemia experienced a heightened mortality risk, suggesting skeletal muscle mass and serum albumin are important prognostic factors.
Heart graphic | Image credit: iaremenko – stock.adobe.com
January 26th 2024

TET2 CHIP an Independent Risk Factor for HFpEF, Study Says

Hayden E. Klein
Researchers found TET2 clonal hematopoiesis of indeterminate potential (CHIP) to be an independent risk factor associated with incident heart failure with preserved ejection fraction (HFpEF).
Stethoscope with heart shape on pink background | makistock - stock.adobe.com
January 25th 2024

Female Patients Less Likely to Receive Guideline-Directed HFrEF Therapies vs Males

Rose McNulty
A recent study found that use of optimal guideline-directed medical therapies after heart failure with reduced ejection fraction (HFrEF) diagnosis is low overall, but especially among female patients compared with male patients.
Man experiencing heart failure | Image credit: lovelyday12 – stock.adobe.com
January 24th 2024

Similar Risk of Death Between Patients With HFimpEF, LVEF Above 40% in DELIVER Trial

Hayden E. Klein
An analysis of the DELIVER trial also revealed an association between dapagliflozin treatment and reduced risk of cardiovascular death among individuals with heart failure with improved ejection fraction (HFimpEF).
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