Heart Failure

The AJMC^® Heart Failure compendium is a comprehensive resource for clinical news and expert insights for the chronic condition in which the heart doesn't pump enough blood due to damaged heart muscle.

Latest News

August 14th 2025

Temporal Shift in Prevalence of Heart Failure Diagnoses and Comorbidities Within 2 US Integrated Health Systems

By Mario Enrico Canonico, MD, PhD
Judith Hsia, MD

August 13th 2025

Finerenone Demonstrates Safety and Efficacy in Heart Failure When Combined With Diuretics

By Sabrina McCrear

August 13th 2025

Genetics, Comorbidities Associated With Cardiomyopathy and Atrial Fibrillation

By Sabrina McCrear

August 8th 2025

Left Bundle Branch Block May Be Key Indicator of Progressive Heart Failure

By Sabrina McCrear

August 1st 2025

Strategies Needed to Address Physical Activity Before, After CVD Events

By Sabrina McCrear

Video Interviews

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August 11th 2025

Sedentary Behaviors Significantly Impact Heart Health, Increase CVD Risk: Melvin Echols, MD

August 8th 2025

Social Drivers of Health Can Impact Regular Exercise, Increase CVD Risk: Melvin Echols, MD

August 4th 2025

Exploring Pregnancy Outcomes in HFpEF and Cardiac Amyloidosis: Rayan Salih, MD

April 2nd 2025

FINEARTS-HF Data Examine Finerenone Across Bilirubin Levels: Jawad Haider Butt, MD, PhD

March 31st 2025

New FINEARTS-HF Findings Provide Clarity on Balancing Risk and Benefit in HF, CKD

November 1st 2024

AHN's Congestive Heart Failure Bundle Cuts Costs, Improves Cardiovascular Care

October 29th 2024

Dr Carol Regueiro: Integrating Team-Based Care, Shadow Bundling for Improved Patient Outcomes

September 30th 2024

Advancing the Field of Valve Interventions for Mitral and Tricuspid Regurgitation

August 26th 2024

Dr Martha Gulati Previews ESC 2024: Obesity, Heart Failure, and the Ongoing Debate on HRT

June 15th 2024

Dr Kathryn Lindley Addresses Barriers to Women’s Heart Disease Diagnosis

Podcasts

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August 5th 2025

What It Takes to Improve Guideline-Based Heart Failure Care With Ty J. Gluckman, MD

August 29th 2023

The Importance of Examining and Preventing Atrial Fibrillation

February 7th 2023

Intermountain Healthcare and Story Health Partner to Optimize Rural Heart Failure Care

December 17th 2021

Investigating the Spreading Uptake of Sacubitril/Valsartan Across the US

September 28th 2021

Reviewing Race and Kidney Disease in the NKF-ASN Task Force Report

November 24th 2019

Podcast: This Week in Managed Care—Heart Disease Treatment and Other Health News

September 22nd 2019

Podcast: This Week in Managed Care—HIV Screening Rates and Other Health News

September 8th 2019

Podcast: This Week in Managed Care—Opioid Prescribing Trends, and Other Health News

August 25th 2019

Podcast: This Week in Managed Care—BRCA Testing Recommendation and Other Health News

May 12th 2019

Podcast: This Week in Managed Care—Drug Prices on Television and Other Health News

Continuing Medical Education

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August 20th 2025

The Economics of Transthyretin-Mediated Amyloidosis: Balancing Equity and Access in Resource Allocation

1 Credit / Cardiology, Neurology

August 20th 2025

Evidence-Based Guidelines Point to Leap in Care for Hypertrophic Cardiomyopathy

1.0 Credit / Cardiology

August 20th 2025

Advancing Immunotherapy in Endometrial Cancer: A Managed Care Perspective on Personalized Care

1.5 Credits / Gynecologic Cancer, Health Equity, Diversity & Inclusion, Oncology, Women's Health

August 20th 2025

Driving Better Outcomes in Hypertrophic Cardiomyopathy: A Managed Care Imperative

1.5 Credits / Cardiology

August 20th 2025

The Evolving Landscape of Transthyretin Amyloidosis Cardiomyopathy: New Therapies and Treatment Strategies

1.5 Credits / Cardiology, Rare Diseases

August 20th 2025

Pulmonary Arterial Hypertension: Real-World Applications of New Therapies and Management Strategies

1.5 Credits / Pulmonology, Cardiology, Rare Diseases

More News

New AI-enhanced echocardiogram model, EchoNext, outperformed cardiologists for accuracy when identifying structural heart disease. | Image credit: Image of an ECG.jpeg

July 25th 2025

AI-Enhanced ECG Expands Access, Reduces Costs for Patients

Sabrina McCrear

An AI model significantly outperformed cardiologists when reviewing ECGs of structural heart disease and may potentially be a step towards increased access and lower costs for early detection of conditions like heart failure and valvular heart disease.

Majority of patients who were female, older in age, or had a history of high blood pressure were less likely to be treated with SLGT2i despite meeting the qualifying criteria and positive outcomes of the treatment. | Image Credit: heart stethoscope - New Africa.jpeg

July 24th 2025

Majority of Qualifying Patients Do Not Receive SGLT2i Therapy

Sabrina McCrear

The majority of patients with heart failure who qualified for sodium-glucose cotransporter 2 inhibitor (SGLT2i) therapy did not receive treatment; a recent study aims to find out why and measure prescription trends.

Social determinants of health combined with heart failure increase the risk of mortality. | Image Credit - lovelyday12 - stock.adobe.com

July 21st 2025

Social Determinants of Health Linked to Congestive Heart Failure Deaths

Sabrina McCrear

Social determinants of health significantly increased mortality risks in patients with congestive heart failure, highlighting urgent care needs.

Carpal tunnel syndrome may prove to be a potential indicator for cardiac amyloidosis. | Image Credit: bluebay2014-stock.adobe.com

July 17th 2025

Carpal Tunnel Syndrome Linked to Cardiac Amyloidosis

Sabrina McCrear

Carpal tunnel syndrome was linked to wild-type transthyretin amyloidosis in new research, highlighting the importance of early diagnosis for better heart failure outcomes.

The approval was based on results from the phase 3 FINEARTS-HF trial. | Image Credit: aznan - stock.adobe.com

July 14th 2025

FDA Approves Finerenone for Heart Failure With Mildly Reduced or Preserved LVEF

Rose McNulty

Finerenone gained FDA approval for heart failure treatment, showcasing significant benefits in reducing cardiovascular events, based on FINEARTS-HF trial results.

Dallas Texas | Image Credit: © SeanPavonePhoto - stock.adobe.com

March 13th 2025

Value-Based Care Is Key to Bringing Cardiology Breakthroughs to Those Who Will Benefit Most

Christina Mattina

On December 10, 2024, cardiologists, researchers, and value-based care experts gathered in Dallas, Texas, to discuss best practices for implementing advances in cardiology care with a value-based mindset, spanning the care continuum from prevention to treatment.

Phoenix Arizona | Image Credit: © Kevin Ruck - stock.adobe.com

March 12th 2025

Closing the Gaps in Cardiac Care With Technology, Collaboration

Christina Mattina

Cardiologists, primary care physicians, and value-based care leaders convened in Phoenix, Arizona, on November 12, 2024, to share case studies and insights on how to align cardiology with the principles of value-based care, including through the application of digital tools.

December 23rd 2024

Top 5 Most-Read Heart Failure Articles of 2024

Hayden E. Klein

Some of the top heart failure research looked at statins and semaglutide for heart failure with preserved ejection fraction, diabetes-related heart failure risks, and the protective cardiovascular effects of COVID-19 vaccination.

December 17th 2024

Top 5 Conference Coverage of 2024

Hayden E. Klein

Health care conferences this year showcased advancements in treatments for chronic obstructive pulmonary disease and sleep apnea, discussions around health policy and economic research, and more.

December 12th 2024

ICYMI: Highlights From ESC Congress 2024

Hayden E. Klein

Top coverage from the 2024 European Society of Cardiology (ESC) Congress focused on screening, treatment, and equity in cardiovascular care.

Tirzepatide box sold as Mounjaro | Image credit: Cynthia – stock.adobe.com

December 5th 2024

How Tirzepatide Benefits Patients With Obesity-Related HFpEF

Hayden E. Klein

A SUMMIT trial analysis showed how tirzepatide improves cardiovascular and kidney health in patients with obesity-related heart failure with preserved ejection fraction (HFpEF).

Doctor writing prescription | Image credit: 18percentgrey – stock.adobe.com

November 18th 2024

SGLT2i Prescriptions for Heart Failure Are Rising, but Vary Across US

Hayden E. Klein

Of the 518 hospitals that had at least 10 eligible discharges, only 11 of them prescribed SGLT2 inhibitors to more than half of their patients.

Liver and stethoscope | Image credit: filins – stock.adobe.com

November 13th 2024

Liver Fibrosis Scores May Hint at Heart Failure Risk

Hayden E. Klein

Noninvasive liver fibrosis scoring systems may help identify who is at risk of developing heart failure.

Man having heart attack | Image credit: JU.STOCKER – stock.adobe.com

November 13th 2024

β-Blockers May Raise Depression Risk for Heart Attack Survivors Without Heart Failure

Hayden E. Klein

One study suggests these drugs could increase depression risk in heart attack survivors who retained normal heart pumping function, while providing no life-saving benefit.

Doctor holding stethoscope to red heart | Image credit: lenets_tan – stock.adobe.com

October 18th 2024

How the Clinical Trial Gender Gap Affects Women’s Heart Care

Hayden E. Klein

The history of women being left out of heart disease research has had significant consequences on heart health care today.

Woman at heart doctor | Image credit: Seventyfour – stock.adobe.com

October 15th 2024

Why Are We Still Seeing Gaps in Women’s Heart Care?

Hayden E. Klein

Women are still being excluded from cardiovascular research trials, and it has a lasting impact on heart disease treatment for women today.

Blood pressure monitor | Image credit: Photo Sesaon – stock.adobe.com

October 11th 2024

Remote Monitoring Program Cuts Heart Failure Readmissions in Half

Hayden E. Klein

UMass Memorial Health–Harrington Hospital reduced 30-day readmissions for congestive heart failure by 50% using artificial intelligence and remote care teams.

Heart and stethoscope | Image credit: New Africa – stock.adobe.com

October 2nd 2024

Optimizing GDMT Could Prevent Over 1 Million HFrEF Deaths Annually

Hayden E. Klein

Despite being eligible for guideline-directed medical therapy (GDMT), tens of millions of patients across the globe are not receiving the heart failure care they need.

Heart failure | Image credit: irissca – stock.adobe.com

September 26th 2024

Adherence to 2021 ESC Heart Failure Guidelines Differed Across Practices

Hayden E. Klein

Inconsistent adherence to the guidelines led to delayed heart failure treatment optimization and underutilization of key therapies.

Hospital sign | Image credit: merrimonc – stock.adobe.com

September 25th 2024

Study Reveals High Variability in Hospital GDMT Scores, Outcomes, Costs

Hayden E. Klein

Hospitals that better utilized heart failure guideline-directed medical therapy (GDMT) had better patient outcomes, with lower mortality rates and costs.

Pediatrician listens to child's heart | Image Credit: © Viacheslav Yakobchuk - stock.adobe.com

September 25th 2024

Sacubitril/Valsartan, Enalapril Show Comparable Efficacy in Pediatric Heart Failure

Christina Mattina

In the PANORAMA-HF trial, children receiving sacubitril/valsartan for their heart failure experienced clinically meaningful improvements similar to those seen in children receiving enalapril, although the former may provide an edge on quality of life.

Wegovy injections and packaging | Image credit: Ole – stock.adobe.com

August 24th 2024

Patients With Heart Failure May Benefit From Weight Loss Drug

Hayden E. Klein

New research indicates that the heart benefits of semaglutide can extend to those with heart failure.

Hospital building | Image credit: Spiroview Inc. – stock.adobe.com

August 23rd 2024

Postdischarge Mortality Remains Unchanged Despite Advances in Heart Failure Care

Hayden E. Klein

Heart failure mortality rates after hospital discharge have seen little improvement since 2010 among Medicare beneficiaries, with real-world outcomes falling short of clinical trial expectations.

Electrocardiogram in hospital surgery operating emergency room | Image credit: totojang1977 – stock.adobe.com

August 15th 2024

Surgery Improves Outcomes for Patients With Atrial Functional Mitral Regurgitation

Hayden E. Klein

A new study found that older patients with atrial functional mitral regurgitation who underwent mitral valve surgery had significantly better outcomes than those who received medical management alone, including lower rates of heart failure hospitalization and death.

$Finerenone, a nonsteroidal, selective mineralocorticoid receptor antagonist (MRA), is the first MRA to reach a primary cardiovascular end point in a phase 3 study in heart failure with mildly reduced or preserved injection fraction. | Image credit: Robert-stock.adobe.com$

August 9th 2024

Finerenone Reduces Cardiovascular Death, HF Events in FINEARTS-HF Trial

Rose McNulty

The investigational therapy for heart failure (HF) with mildly reduced or preserved injection fraction met its primary end point in the phase 3 trial, Bayer announced.