Heart Failure

In patients with ejection fraction greater than 40% who were stabilized after a worsening heart failure event, use of combination sacubitril/valsartan led to greater reduction in plasma NT-proBNP levels compared with valsartan alone.

This is the first study to investigate a potential connection between anthracycline chemotherapy and risk of heart failure (HF) in young adult cancer survivors.

The effect of education on survival outcomes was evaluated both overall and as it related to cardiovascular disease (CVD).

Causes of heart failure (HF), medication usage, and HF-related hospitalization and death were investigated among patients from 40 countries and 4 economic levels.

Individuals living with heart failure in the United States are expected to top 8 million by 2030 vs the close to 6 million living with the disease between 2015 and 2018.

Many adolescents and young adults (AYAs) with advanced heart disease prefer to be involved in decisions that have an impact on their medical care, but new survey results show there is a great need for educational communication efforts that involve their caregivers and clinicians.

This subanalysis of data from the VIRGO study encompassed 2979 patients who had an acute myocardial infarction (AMI), or heart attack, between ages 18 and 55 years; outcomes evaluated included all-cause and cause-specific acute events requiring hospitalization in the year after discharge for a heart attack.

Accelerating the safe implementation guideline-directed medical therapy has also been shown to reduce heart failure–related morbidity and mortality, underscoring the need for more integration into current care.

The investigators of this study wanted to know if hospitals that cared for a high proportion of Black patients delivered care for heart failure (HF) that differed in quality from that provided by other hospitals.

Using data from the PROVE-HF study, investigators conducted a subanalysis of outcomes among patients receiving sacubitril/valsartan who did and did not have ischemic heart disease.

At present, there are no approved therapies for pre–heart failure with preserved ejection fraction (pre-HFpEF); instead, cardiovascular risk factor management is often utilized in this patient population.

There are higher risks of several major adverse cardiovascular events (MACEs) following intracerebral hemorrhage (ICH), and they include recurrent ICH, ischemic stroke, and myocardial infarction.

Data from the PANORAMA-HF and PARADIGM-HF trials support the recommendation for approval from the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency.

This study of the public health landscape in New York City investigated the interplay between social determinants of health (SDOH), chronic health conditions, and inequities in social factors, with a focus on cardiovascular disease (CVD).

Baseline risk assessment that includes prior treatment history for cancer, prior cardiovascular events, and markers for potential heart damage are all important, emphasizes Tochi M. Okwuosa, DO, cardiologist and director of cardio-oncology at Rush University Medical Center in Chicago.

Optimizing utilization of sacubitril/valsartan for treatment of heart failure could improve provider performance in the Bundled Payments for Care Improvement initiative and the Medicare Shared Savings Program.

Speaking at the 72nd American College of Cardiology Scientific Session in New Orleans on Sunday, Clyde W. Yancy, MD, MSc, the vice dean for diversity and inclusion at the Feinberg School of Medicine at Northwestern University, challenged the audience to rethink what success looks like in health care.

Results for the STELLAR trial, presented at the 72nd American College of Cardiology (ACC) Scientific Session Together With the World Congress of Cardiology, hit nearly every mark: patients taking sotatercept improved their performance on a 6-minute walk test by 40.8 meters, which was the primary end point, and achieved 8 of 9 secondary end points.

Potential disparities in care highlight the great need for tailored cardiovascular health (CVH) interventions among bisexual female individuals, according to a recent study.

Results from the CLEAR Outcomes trial were presented today at the 72nd American College of Cardiology (ACC) Scientific Session Together With the World Congress of Cardiology. Plans for a broader label are in the works.

Braden Manns, MD, MSc, a nephrologist and health economics researcher at the University of Calgary in Canada, will present the results of a randomized trial evaluating the impact of removing co-payments for drugs that treat chronic conditions on cardiovascular outcomes during the American College of Cardiology Scientific Sessions in New Orleans, Louisiana, on Sunday, March 5.

Outcomes from the loop diuretics were compared in this analysis, with study participants from the TRANSFORM-HF trial matched 1:1, all having been hospitalized for either do novo disease or worsening chronic disease.

Tochi M. Okwuosa, DO, Rush University Medical Center, discusses ways in which cancer treatments can adversely affect heart health outcomes for patients under the care of oncologists.

Patients with heart failure and high comorbidity burdens who received postdischarge noninvasive telemonitoring and nurse telephone coaching showed better survival outcomes than those who received standard care.

Implications of these findings include a more clear understanding of the burden imposed by heart failure (HF), which encompasses the cost of care and adverse health outcomes.