Heart Failure

The AJMC® Heart Failure compendium is a comprehensive resource for clinical news and expert insights for the chronic condition in which the heart doesn't pump enough blood due to damaged heart muscle.

Latest News

Dallas Texas | Image Credit: © SeanPavonePhoto - stock.adobe.com
Value-Based Care Is Key to Bringing Cardiology Breakthroughs to Those Who Will Benefit Most

March 13th 2025

On December 10, 2024, cardiologists, researchers, and value-based care experts gathered in Dallas, Texas, to discuss best practices for implementing advances in cardiology care with a value-based mindset, spanning the care continuum from prevention to treatment.

Phoenix Arizona | Image Credit: © Kevin Ruck - stock.adobe.com
Closing the Gaps in Cardiac Care With Technology, Collaboration

March 12th 2025

the top 5 heart failure content of 2024
Top 5 Most-Read Heart Failure Articles of 2024

December 23rd 2024

Top 5 conference coverage of 2024
Top 5 Conference Coverage of 2024

December 17th 2024

Highlights From ESC Congress 2024
ICYMI: Highlights From ESC Congress 2024

December 12th 2024

Continuing Medical Education
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June 18th 2025

Exploring Transthyretin-Mediated Amyloidosis and Its Phenotypes: A Comprehensive Approach to Patient Treatment

1.5 Credits / Cardiology, Neurology, Rare Diseases
June 18th 2025

The Economics of Transthyretin-Mediated Amyloidosis: Balancing Equity and Access in Resource Allocation

1 Credit / Cardiology, Neurology
June 18th 2025

Evidence-Based Guidelines Point to Leap in Care for Hypertrophic Cardiomyopathy

1.0 Credit / Cardiology

More News

Doctor using stethoscope on patient's heart | Image credit: joyfotoliakid – stock.adobe.com
March 23rd 2024

Midodrine Use Linked to Decrease in HFrEF-Related ED Visits

Hayden E. Klein
However, researchers saw higher risks of respiratory failure, longer stays in the intensive care unit, increased hospitalizations, and elevated mortality rates in patients with heart failure with reduced ejection fraction (HFrEF) taking the antihypotensive medication.
Cash money stethoscope cost | Image credit: adragan – stock.adobe.com
March 21st 2024

Perceived Economic Burden Linked to HF Mortality Risk, Study Says

Hayden E. Klein
Increased perceived economic burden (PEB) was associated with an increased risk of mortality and poorer health status among patients with acute decompensated heart failure (HF).
Doctor visit during pregnancy | Image credit: pressmaster – stock.adobe.com
March 12th 2024

Severe Prenatal Grief May Increase Child’s Heart Failure Risk

Hayden E. Klein
Research found that maternal loss of a partner or older child, as well as the loss of a close relative due to unnatural causes in the year before or during pregnancy, were linked to a heightened risk of heart failure in offspring.
Atorvastatin | Image credit: Soni's – stock.adobe.com
February 23rd 2024

30-Day Atorvastatin Improved Brachial Artery FMD in Patients With HFpEF, but More Research Is Needed

Hayden E. Klein
This study was the first of its kind to explore how taking statin medication affects blood vessel function and exercise response in patients with heart failure with preserved ejection fraction (HFpEF), although the cohort only included 16 patients.
BMI scale | Image credit: Olivier Le Moal – stock.adobe.com
February 23rd 2024

There Is No Interaction Between BMI and SGLT2 Inhibitor Efficacy in HF, Review Finds

Hayden E. Klein
Among patients with heart failure (HF), those taking dapaglifozin or empaglifozin had a 30% odds reduction in HF hospitalization, 14% odds reduction in cardiovascular mortality, and a 10% odds reduction in all-cause mortality compared with patients taking placebo.
Women hula hooping | Image credit: Rawpixel.com – stock.adobe.com
February 21st 2024

More Physical Activity Linked to Reduced HF Risk in Older Women

Hayden E. Klein
Increased daily step count was linked to reduced risks of overall heart failure (HF) and HF with preserved or reduced ejection fraction.
Pacemaker | Image credit: Birgit Reitz-Hofmann – stock.adobe.com
February 5th 2024

Permanent Pacemaker Implantation Frequently Follows Tricuspid Valve Surgery, Study Finds

Hayden E. Klein
Among Medicare beneficiaries, implantation was especially frequent for female patients and those undergoing tricuspid valve replacement with or without concomitant left-sided heart surgeries.
Heart | Image credit: abhijith3747 - stock.adobe.com
January 28th 2024

Low Muscle Mass, Hypoalbuminemia Increase Mortality Risk in ADHF

Rose McNulty
Patients admitted to the hospital with acute decompensated heart failure (ADHF) who also had low muscle mass and hypoalbuminemia experienced a heightened mortality risk, suggesting skeletal muscle mass and serum albumin are important prognostic factors.
Heart graphic | Image credit: iaremenko – stock.adobe.com
January 26th 2024

TET2 CHIP an Independent Risk Factor for HFpEF, Study Says

Hayden E. Klein
Researchers found TET2 clonal hematopoiesis of indeterminate potential (CHIP) to be an independent risk factor associated with incident heart failure with preserved ejection fraction (HFpEF).
Stethoscope with heart shape on pink background | makistock - stock.adobe.com
January 25th 2024

Female Patients Less Likely to Receive Guideline-Directed HFrEF Therapies vs Males

Rose McNulty
A recent study found that use of optimal guideline-directed medical therapies after heart failure with reduced ejection fraction (HFrEF) diagnosis is low overall, but especially among female patients compared with male patients.
Man experiencing heart failure | Image credit: lovelyday12 – stock.adobe.com
January 24th 2024

Similar Risk of Death Between Patients With HFimpEF, LVEF Above 40% in DELIVER Trial

Hayden E. Klein
An analysis of the DELIVER trial also revealed an association between dapagliflozin treatment and reduced risk of cardiovascular death among individuals with heart failure with improved ejection fraction (HFimpEF).
the top 5 heart failure content of 2023
December 23rd 2023

Top 5 Heart Failure Content of 2023

Hayden E. Klein
The top 5 most-viewed heart failure (HF) content of the year focused on how walking can improve HF outcomes, a link between HF and carpal tunnel syndrome, and more.
The top 5 conference coverage of 2023
December 19th 2023

Top 5 Conference Coverage of 2023

Hayden E. Klein
Our top conference coverage of 2023 covered a range of topics, including cardiovascular disease, heart failure, breast cancer, and chronic lymphocytic leukemia.
Patient and caretaker | Image credit: Rido – stock.adobe.com
December 7th 2023

Patients With HFrEF, HFpEF See Different Functional Capacity Benefits With Dapagliflozin

Hayden E. Klein
The DETERMINE-Reduced and DETERMINE-Preserved trials demonstrated varying benefits of dapagliflozin on Kansas City Cardiomyopathy Questionnaire Total Symptom Score and Physical Limitation Scale as well as 6-minute walk distance.
dapagliflozin | Image credit: luchschenF – stock.adobe.com
December 6th 2023

Study: SGLT2is Should Be Continued Despite Initial eGFR Decline in Patients With HFmrEF/HFpEF

Hayden E. Klein
Despite an initial drop in estimated glomerular filtration rate (eGFR) after 1 month of dapagliflozin, researchers say this is not associated with subsequent risk of cardiovascular or kidney events for patients with heart failure with mildly reduced ejection fraction (HFmrEF) or preserved ejection fraction (HFpEF).
AI heart | Image credit: LeArchitecto – stock.adobe.com
November 20th 2023

AI App Predicts Heart Failure Early by Listening to People Talk

Chelsie Derman
An artificial intelligence (AI) app can detect increased fluid in lungs by simply hearing voice changes over time—and the increased fluid in lungs can be a sign of heart failure.
Hospital corridor | Image credit: spotmatikphoto – stock.adobe.com
November 18th 2023

Following Hospitalization, de Novo HF Outcomes Better Than Worsening HF

Hayden E. Klein
The study also identified similar 12-month outcomes between torsemide and furosemide regardless of heart failure (HF) type.
Diverse group holding paper heart | Image credit: Jezper – stock.adobe.com
November 16th 2023

AHA’s New Risk Calculator Takes Race Out of Heart Disease Predictions

Hayden E. Klein
The tool assesses the risk of heart attack, stroke, and, for the first time, heart failure, offering a more comprehensive perspective on cardiovascular health.
Woman taking aspirin | Image credit: fizkes – stock.adobe.com
November 15th 2023

Benefits of Excluding Aspirin From Antithrombotic Regimen in Patients With LVADs

Hayden E. Klein
New research highlighted how aspirin is unnecessary in antithrombotic regimens for patients with advanced heart failure and fully magnetically levitated left ventricular assist devices (LVADs).
What We’re Reading: Weight Loss Drug May Reduce Heart Risks; COVID-19 Vaccine Opposition; Lawmakers Seek to Restrict Issue 1 Abortion Amendment
November 13th 2023

What We’re Reading: Weight Loss Drug May Reduce Heart Risks; COVID-19 Vaccine Opposition; Ohio Abortion Amendment

AJMC Staff
The weight loss drug semaglutide showed significant cardiovascular benefits; Texas and Florida are restricting the promotion of COVID-19 vaccines; some Ohio legislators are seeking to block courts from interpreting the state’s recently passed constitutional amendment that created a right to abortion.
what we're reading logo
November 7th 2023

What We’re Reading: AI Heart Attack Detection; FDA Menthol Ban; Shooting Survivor Care Obstacles

AJMC Staff
Artificial intelligence (AI) could help detect heart attack risk signs and prevent sudden cardiac death; Advocates demand the Biden administration finalize the proposed FDA ban on menthol cigarettes; Gun violence survivors and their families have many ongoing medical needs.
Entresto box | Image Credit: omar – stock.adobe.com
October 26th 2023

Sacubitril/Valsartan Reduces Natriuretic Peptide Levels, Improves QOL in Patients With HFpEF

Hayden E. Klein
The improvement in quality of life (QOL) seen with use of sacubitril/valsartan for heart failure with preserved ejection fraction (HFpEF) could potentially result in more favorable clinical results.
Generic pills | Image Credit: Mr.Ilkin – stock.adobe.com
October 24th 2023

GALACTIC Trial Reveals Less Successful RAAS Inhibitor Uptitration in Women Than Men

Hayden E. Klein
Uptitration of renin-angiotensin-aldosterone system (RAAS) inhibitors was less successful in women than men with acute heart failure (AHF), especially in those with HF with reduced ejection fraction.
Anemia label on blood test | Image Credit: vchalup – stock.adobe.com
October 23rd 2023

Anemia Contributes to Exercise Intolerance in HFpEF, Study Finds

Patrick Campbell Hayden E. Klein
Patients with heart failure with preserved ejection fraction (HFpEF) may experience worsened exercise tolerance if they also have anemia.
Javed Butler, MD, MPH, MBA
October 13th 2023

Dr Javed Butler: How STEP-HFpEF Findings on Semaglutide Translate to Clinical Practice

Hayden E. Klein
Positive results from STEP-HFpEF indicate that semaglutide can improve quality of life and functional capacity in patients with obesity-related heart failure with preserved ejection fraction (HFpEF), but large outcomes trials are needed to confirm this, said Javed Butler, MD, MPH, MBA.
Emergency department | Image Credit: nilsversemann – stock.adobe.com
October 10th 2023

Acute Heart Attack Care Faces Prolonged Challenges Post COVID-19

Hayden E. Klein
Despite improvements, hospitals struggle to meet prepandemic standards in door-to-balloon time.
Jennifer Sturgill, DO, Central Ohio Primary Care
October 3rd 2023

Dr Jennifer Sturgill Addresses IRA Drug Price Negotiations and the Current Drug Shortage

Maggie L. Shaw
Jennifer Sturgill, DO, Central Ohio Primary Care, discusses how shortages of antibiotics and medications for attention-deficit/hyperactivity disorder have affected primary care, as well as addresses the impact on heart failure care of CMS’ recent announcement of the first 10 drugs up for price negotiation in 2026 under the Inflation Reduction Act (IRA).
Zachary Cox, PharmD
September 28th 2023

How Will DICTATE-AHF Findings Affect Clinical Practice? Dr Zachary Cox Explains

Hayden E. Klein
The findings of DICTATE-AHF have several implications for cardiologists treating patients with type 2 diabetes, said Zachary Cox, PharmD, professor at Lipscomb University College of Pharmacy.
glowing human heart in hands | Image credit: IBEX.Media – stock.adobe.com
September 22nd 2023

BNP Levels May Not Be Effective Prognostic Tool for Patients With Cardiogenic Shock Using VADs

Hayden E. Klein
While B-type natriuretic peptide (BNP) levels remain high in patients with end-stage heart failure with cardiogenic shock, these levels lose their prognostic value in patients using ventricular assist devices (VADs).
pharmacist giving patient a prescription | Image credit: Clayton D/peopleimages.com – stock.adobe.com
September 21st 2023

Tailored EHR Alerts Fail to Improve Acute HF Medication Prescription at Discharge

Hayden E. Klein
A tailored electronic health record (EHR) alert system did not significantly increase the prescription of guideline-directed medical therapies (GDMT) at hospital discharge for patients with acute heart failure (AHF).
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