Heart Failure

The AJMC^® Heart Failure compendium is a comprehensive resource for clinical news and expert insights for the chronic condition in which the heart doesn't pump enough blood due to damaged heart muscle.

Latest News

Researchers measured physical activity trajectories before and after CVD events like coronary heart disease, stroke, and heart failure. | Image Credit: LIGHTFIELDSTUDIOS - stock.adobe.com

Strategies Needed to Address Physical Activity Before, After CVD Events

By Sabrina McCrear

August 1st 2025

Black women had lower moderate-to-vigorous intensity physical activity scores when compared with Black and White men and their White female counterparts, highlighting the need for support across patient subgroups.

New AI-enhanced echocardiogram model, EchoNext, outperformed cardiologists for accuracy when identifying structural heart disease. | Image credit: Image of an ECG.jpeg

AI-Enhanced ECG Expands Access, Reduces Costs for Patients

By Sabrina McCrear

July 25th 2025

Majority of patients who were female, older in age, or had a history of high blood pressure were less likely to be treated with SLGT2i despite meeting the qualifying criteria and positive outcomes of the treatment. | Image Credit: heart stethoscope - New Africa.jpeg

Majority of Qualifying Patients Do Not Receive SGLT2i Therapy

By Sabrina McCrear

July 24th 2025

Social determinants of health combined with heart failure increase the risk of mortality. | Image Credit - lovelyday12 - stock.adobe.com

Social Determinants of Health Linked to Congestive Heart Failure Deaths

By Sabrina McCrear

July 21st 2025

Carpal tunnel syndrome may prove to be a potential indicator for cardiac amyloidosis. | Image Credit: bluebay2014-stock.adobe.com

Carpal Tunnel Syndrome Linked to Cardiac Amyloidosis

By Sabrina McCrear

July 17th 2025

Continuing Medical Education

August 3rd 2025

The Economics of Transthyretin-Mediated Amyloidosis: Balancing Equity and Access in Resource Allocation

1 Credit / Cardiology, Neurology

August 3rd 2025

Evidence-Based Guidelines Point to Leap in Care for Hypertrophic Cardiomyopathy

1.0 Credit / Cardiology

August 3rd 2025

Advancing Immunotherapy in Endometrial Cancer: A Managed Care Perspective on Personalized Care

1.5 Credits / Gynecologic Cancer, Health Equity, Diversity & Inclusion, Oncology, Women's Health

August 3rd 2025

Driving Better Outcomes in Hypertrophic Cardiomyopathy: A Managed Care Imperative

1.5 Credits / Cardiology

August 3rd 2025

The Evolving Landscape of Transthyretin Amyloidosis Cardiomyopathy: New Therapies and Treatment Strategies

1.5 Credits / Cardiology, Rare Diseases

August 3rd 2025

Pulmonary Arterial Hypertension: Real-World Applications of New Therapies and Management Strategies

1.5 Credits / Pulmonology, Cardiology, Rare Diseases

More News

Heart graphic

May 15th 2021

AHF Management Among Elderly, Super-Elderly Needs Improvement in Japan

Rates of acute heart failure (AHF) have recently been rapidly increasing among elderly and super-elderly patients in Japan, and this study investigated rates of all-cause death and mode of death among this patient population.

Clinical trial alert

May 14th 2021

Studies With Potential to Change the Science of Heart Failure Management

These 4 studies were pegged as “ones to watch” during the American College of Cardiology (ACC) annual briefing on results for consumers. They will be presented in the opening session of late-breaking clinical trial results on day 1 of ACC.21.

blood clot

May 6th 2021

Studies Highlight Role of Stress, Social Disadvantage in Heart Health Disparities

Both studies were featured during the American College of Cardiology's annual briefing on results for consumers. They will be presented during the 70th Scientific Session, which is set for May 15-17, 2021.

Secondhand smoke exposure

May 5th 2021

Greater Potential for Heart Failure Linked to Secondhand Smoke Exposure

Compared with nonsmokers who did not have recent exposure to secondhand smoke, a 35% greater chance for heart failure was seen among those with recent exposure to the toxic fumes.

Measuring heart function

April 28th 2021

Factors That Determine VO2 Max Importance as Measure of Heart Failure Severity

Right ventricular systolic function evaluated through VO2 max is a more accurate measure of functional capacity of persons with heart failure compared with left ventricular systolic function.

COVID molecule overlaying ECG

April 26th 2021

Rare Cases of New-Onset Heart Failure Linked to COVID-19

Findings from a new study out of Mount Sinai in New York show a small but rare chance of developing new-onset heart failure following hospitalization for COVID-19.

Electronic medical record

April 22nd 2021

Accurately Identifying Heart Failure in Patients With COPD

A new approach to identifying and defining heart failure among patients with chronic obstructive pulmonary disease (COPD) involves combining information gleaned from reviewing their electronic medical records and examination charts.

Person pinching fat

April 20th 2021

Stable Severe Obesity Shown to Increase Severity, Risk of Long-term Heart Failure

Overweight and obese adults, whose body mass index trended upward in a recent UK study, had higher risk of heart failure, all-cause mortality, and cardiovascular disease–related mortality.

Physical Disorders May Lessen Effectiveness of Combination Therapy for HFrEF

April 16th 2021

Physical Disorders May Lessen Effectiveness of Combination Therapy for HFrEF

This recent study out of Japan compared the use of renin-angiotensin system inhibitors and β-blockers among patients with heart failure, both those who had physical limitations and those who did not.

Doctor reviewing computerized heart image

April 15th 2021

Biomarkers May Predict Hospitalization Among Persons With Heart Failure, AFib

Elevated levels of 2 inflammatory biomarkers may indicate a greater heart failure hospitalization risk for patients who have diagnosed atrial fibrillation.

illustration of anatomical heart

April 9th 2021

Delirium Associated With Decreased Functional Improvement Among Patients With HF

Veterans Affairs data show that among patients with heart failure admitted to skilled nursing facilities, those with delirium exhibited decreased rates of functional recovery.

Mother holding heart over pregnant belly

April 7th 2021

Possible Link Found Between Adult-Onset Heart Failure, Preterm Birth

A higher risk of adult-onset heart failure was found in this Swedish study that investigated its association with singleton live births before 37 weeks gestation.

Older Asian couple

April 2nd 2021

Dapagliflozin Benefits Women and Men With Heart Failure

A recent subgroup analysis of the DAPA-HF study investigated possible clinical outcome differences between women and men following the addition of dapagliflozin to their treatment regimens.

Modifiable Factors Increase Risk of Young-Onset Heart Failure

March 31st 2021

Modifiable Factors Increase Risk of Young-Onset Heart Failure

Morbidity and mortality in individuals younger than 55 years with heart failure may be attenuated by targeting possible age-dependent risk factors

Data on the human heart

March 25th 2021

KCCQ-OS Better Able to Predict Changes in Health Status, Study Says

After a 12-month follow-up of patients in the CHAMP-HF registry, Kansas City Cardiomyopathy Questionnaire Overall Summary Score (KCCQ-OS) was shown to be more prognostically accurate compared with New York Heart Association functional class.

Electrocardiogram

March 23rd 2021

Potential Novel Heart Failure Diagnosis Method for Patients With AFib

Among patients with atrial fibrillation (AFib) in the RATE-AF trial, the index-beat approach produced superior results on a potential diagnosis of heart failure vs consecutive-beat methods.

Heart in weathered hands

March 19th 2021

Heart Failure May Be Predicated by Subtle Impairment, Researchers Say

Reduced left ventricular ejection fraction, longitudinal strain, and circumferential strain have possibly been linked to development of heart failure among elderly individuals.

Caregiver and patients holding hands

March 17th 2021

Profound Impact of Heart Failure Seen in Patients, Caregivers Alike

Responses from a study of in-person focus groups show that not only do patients report adverse effects on quality of life, physical well-being, and mental health but that their caregivers do as well.

Twisted cigarette

March 13th 2021

Greater Risk of Heart Failure Seen in Individuals With Smoking History

In this Mendelian randomization study, higher odds of developing heart failure were seen in regular vs never smokers and in current vs former smokers.

Money

March 10th 2021

An Excess of Heart Failure–Related Deaths Seen in Rural Counties

Heart failure has been shown to be a contributing factor in more deaths in rural vs urban counties in which cardiovascular disease was pinpointed as the underlying cause of death.

Neon kidneys

March 4th 2021

Patients With HFpEF Administered Sacubitril/Valsartan Gain Renal Benefits

Study results from Taiwan of patients with heart failure and comorbid chronic kidney disease show a drop in the risk of renal function decline among patients with heart failure with preserved ejection fraction (HFpEF) administered sacubitril/valsartan.

What We're Reading: Merck to Produce J&J Vaccine; Fauci on Shifting Vaccine Strategies; HVAD Pump Implant Kits Recalled

March 2nd 2021

What We're Reading: Merck to Produce J&J Vaccine; Fauci on Shifting Vaccine Strategies; HVAD Pump Implant Kits Recalled

Matthew Gavidia

Merck and Johnson & Johnson (J&J) partner to produce J&J's COVID-19 vaccine; Anthony Fauci, MD, warns against shifting to a single-dose strategy for approved 2-shot vaccines; Medtronic recalls its HVAD Pump Implant Kits.

Older people exercising

February 27th 2021

Varying Physical Activity for Patients With HFpEF Fails to Increase VO2 Levels

A comparison of patients with heart failure with preserved ejection fraction (HFpEF) randomized to 1 of 2 physical activities did not show a significant increase in peak oxygen consumption (VO2) vs guideline-based physical activity.

Heart in hands

February 22nd 2021

Hypertensive Pregnancy Disorders Linked to Cardiac Abnormalities

Compared with women with normotensive pregnancies, women who develop various hypertensive disorders during pregnancy have a greater risk of cardiac structure abnormalities in the decade after pregnancy.

Entresto Wins First FDA Nod in Hard-to-Treat Type of Heart Failure

February 16th 2021

Entresto Wins First FDA Nod in Hard-to-Treat Type of Heart Failure

Novartis' drug, which combines sacubitril and valsartan, is the first to directly treat patients with heart failure with preserved ejection fraction.

Enhanced heart graphic

February 15th 2021

Researchers Call for Earlier Monitoring of Cardiac Function Among High-risk Patients

An analysis of 30-year data on participants from the Augusta Heart study shows that Black individuals begin to exhibit potential signs of congestive heart failure earlier than their White counterparts.

Hospital room

February 11th 2021

Hospital Admissions for Heart Failure on the Rise

A comparison of 2 time periods shows that following an initial decline, hospital admissions for primary management of heart failure rose between 2014 and 2017.

Jaime Murillo, MD

February 9th 2021

Heart Failure Management During COVID-19

The program is closed with a discussion on how the coronavirus pandemic has affected the standard protocol for treating patients with heart failure.

Cup of coffee with scattered beans

February 9th 2021

Drink More Coffee, Possibly Decrease Your Heart Failure Risk, Study Says

Machine learning of data from 3 well-known heart studies shows a decline in heart failure risk from drinking at least 1 cup of caffeinated coffee each day.

Risk being erased

February 4th 2021

High-Protein Diet Reduces Cardiometabolic Risk Among Patients With Heart Failure

Compared with a standard-protein diet, a high-protein diet reduced several markers of cardiometabolic risk in patients with heart failure and diabetes who were considered overweight or obese.

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